Well Told Grants

Grants / Department of Health and Human Services / Centers for Disease Control and Prevention - ERA

RFA-CK-25-182: Enhanced Surveillance and Control of Endemic and Emerging Arboviruses in Puerto Rico

Closed Closed February 28, 2025 Opportunity RFA-CK-25-182

This grant is closed. A newer notice from the same program is open now: NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional) (PA-27-100). Status: Due dates in the notice, expires April 5, 2027. It is in our archive of Centers for Disease Control and Prevention - ERA notices from 2024.

Centers for Disease Control and Prevention - ERA offered grants of up to $5.0 million (at least $500,000) to the applicants described in the notice. It expected to make one award worth $25.0 million in total. Applications closed on February 28, 2025.

From the official notice on Grants.gov, last changed December 27, 2024. Checked November 7, 2026.

Key dates

PostedDecember 27, 2024
DeadlineFebruary 28, 2025
Archived by Grants.govMarch 31, 2025

Who can apply

This opportunity was open to the applicants described in the notice.

Ponce Medical School Foundation Inc in Ponce Health Sciences University (PHSU) in Puerto Rico is the only eligible applicant.

Is this a realistic fit?

What the grant funds

The purpose of this notice of funding opportunity (NOFO) is to strengthen an established research platform for arboviruses in hospital and community settings in Puerto Rico, identify emerging and endemic pathogens like dengue and Oropouche viruses, improve patient management, and evaluate prevention and control strategies. The core objectives include: 1) strengthen hospital surveillance of acute febrile illness (AFI) to ensure early detection of emerging arboviruses and other pathogens; 2) use the established AFI surveillance platform to conduct clinical research on dengue and other arboviral diseases, including among special populations such as women and children; 3) maintain and enhance the community cohort to assess incidence and prevalence of arboviral infections and other AFIs, while also evaluate the effectiveness of vector control strategies; 4) strengthen and modernize infrastructure for project data management and analysis, ensuring the surveillance platform is capable of handling large, complex datasets in real-time; and 5) strengthen collaborations with the local government, community leaders, and other interest holders to ensure the continuity of the established program while fostering an environment of rapid and effective communication and cooperation.

Category: Health.

Who has won Prevention of Disease, Disability, and Death by Infectious Diseases grants before

From fiscal 2021 to 2025, Prevention of Disease, Disability, and Death by Infectious Diseases (93.084) awarded $241 million across 128 grant awards, an average of $1.9 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
Puerto Rico Science, Technology, and Research TrustPuerto Rico4$14.5 million
Massachusetts Department of Public HealthMassachusetts1$11.6 million
Emory UniversityGeorgia3$11.5 million
Uganda Virus Research Institute1$8.7 million
Ponce Medical School Foundation IncPuerto Rico2$8.7 million

Top states: Massachusetts ($26.4 million), Puerto Rico ($23.2 million), California ($22.9 million), Georgia ($20.0 million), Maryland ($14.0 million).

Applying now

This notice no longer takes applications. Apply under the newer notice, PA-27-100, which is open now.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is RFA-CK-25-182 still open?

No. It closed on February 28, 2025. A newer notice is open: PA-27-100, due dates in the notice, expires April 5, 2027.

Who can apply for Enhanced Surveillance and Control of Endemic and Emerging Arboviruses in Puerto Rico?

Centers for Disease Control and Prevention - ERA accepted applications from the applicants described in the notice. The notice adds further conditions, so read its eligibility section.

What is the deadline for Enhanced Surveillance and Control of Endemic and Emerging Arboviruses in Puerto Rico?

Closed February 28, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

Awards of up to $5.0 million each. About $25.0 million in total for one award.

Who has won Prevention of Disease, Disability, and Death by Infectious Diseases grants before?

The largest recipients over five fiscal years were Puerto Rico Science, Technology, and Research Trust, Massachusetts Department of Public Health, Emory University. The program made 128 awards worth $241 million in that time.

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