RFA-CK-22-004: Optimization and Standardization of Methods to Suppress Ixodes scapularis and Disrupt Enzootic Pathogen Transmission in Settings Posing an Elevated Risk to Humans
Closed
This grant is closed. A newer notice from the same program is open now: NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional) (PA-27-100). Status: Due dates in the notice, expires April 5, 2027. It is in our archive of Centers for Disease Control and Prevention - ERA notices from 2021.
Centers for Disease Control and Prevention - ERA offered grants of up to $1.0 million (at least $750,000) to nonprofits, colleges and universities, state and local governments and tribes. It expected to make one award worth $5.0 million in total. Applications closed on February 15, 2022.
From the official notice on Grants.gov, last changed January 13, 2022. Checked November 7, 2026.
- Award ceiling$1.0 million
- Award floor$750,000
- Total funding$5.0 million
- Expected awards1
- Cost sharingNot required
- Funding typeCooperative Agreement
Key dates
| Posted | December 14, 2021 |
|---|---|
| Deadline | February 15, 2022 |
| Archived by Grants.gov | March 15, 2022 |
Who can apply
This opportunity was open to nonprofits, colleges and universities, state and local governments and tribes.
All 12 applicant types the notice lists
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
The following types of Higher Education Institutions are always encouraged to apply for CDC support as Non-profit Public or Non-profit Private Institutions of Higher Education: Hispanic-serving Institutions Historically Black Colleges and Universities (HBCUs) Tribally Controlled Colleges and Universities (TCCUs) Alaska Native and Native Hawaiian Serving Institutions Nonprofits (Other than Institutions of Higher Education) Private non-profit institutions of higher education Eligible Agencies of the Federal Government Faith-based or Community-based Organizations U.S. Territory or Possession Regional Organizations Bona Fide Agents: A Bona Fide Agent is an agency/organization identified by the state as eligible to submit an application under the state eligibility in lieu of a state application. If applying as a bona fide agent of a state or local government, a legal, binding agreement from the state or local government as documentation of the status is required. Attach with "Other Attachment Forms." Federally Funded Research and Development Centers (FFRDCs): FFRDCs are operated, managed, and/or administered by a university or consortium of universities, other not-for-profit or nonprofit organization, or an industrial firm, as an autonomous organization or as an identifiable separate operating unit of a parent organization. A FFRDC meets some special long-term research or development need which cannot be met as effectively by an agency's existing in-house or contractor resources. FFRDC's enable agencies to use private sector resources to accomplish tasks that are integral to the mission and operation of the sponsoring agency. For more information on FFRDCs, go to https://gov.ecfr.io/cgi-bin/searchECFR
Is this a realistic fit?
- Past Prevention of Disease, Disability, and Death by Infectious Diseases awards averaged $1.9 million; this notice allows up to $1.0 million per award.
- No cost sharing or match is required.
What the grant funds
This NOFO intends to support research to: 1) optimize and standardize implementation of existing strategies to reduce the abundance of host-seeking Ixodes scapularis nymphs infected with human pathogens, especially Lyme disease spirochetes (DIN); 2) evaluate efficacy and reproducibility of operational use (e.g., in the hands of pest control professionals or the public, as appropriate) of these protocols in high-risk settings (e.g., wooded residential properties, high-use wooded recreational areas) across the Midwest, Northeast and Mid-Atlantic United States where baseline DIN is elevated; and 3) develop standard operating procedures that may be used by homeowners or vector control professionals to implement these interventions within communities at risk for exposure to Lyme disease spirochetes and other I. scapularis-borne pathogens.
Who has won Prevention of Disease, Disability, and Death by Infectious Diseases grants before
From fiscal 2021 to 2025, Prevention of Disease, Disability, and Death by Infectious Diseases (93.084) awarded $241 million across 128 grant awards, an average of $1.9 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Puerto Rico Science, Technology, and Research Trust | Puerto Rico | 4 | $14.5 million |
| Massachusetts Department of Public Health | Massachusetts | 1 | $11.6 million |
| Emory University | Georgia | 3 | $11.5 million |
| Uganda Virus Research Institute | 1 | $8.7 million | |
| Ponce Medical School Foundation Inc | Puerto Rico | 2 | $8.7 million |
Applying now
This notice no longer takes applications. Apply under the newer notice, PA-27-100, which is open now.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is RFA-CK-22-004 still open?
No. It closed on February 15, 2022. A newer notice is open: PA-27-100, due dates in the notice, expires April 5, 2027.
Who can apply for Optimization and Standardization of Methods to Suppress Ixodes scapularis and Disrupt Enzootic Pathogen Transmission in Settings Posing an Elevated Risk to Humans?
Centers for Disease Control and Prevention - ERA accepted applications from nonprofits, colleges and universities, state and local governments and tribes. The notice adds further conditions, so read its eligibility section.
What is the deadline for Optimization and Standardization of Methods to Suppress Ixodes scapularis and Disrupt Enzootic Pathogen Transmission in Settings Posing an Elevated Risk to Humans?
Closed February 15, 2022. Applications are no longer accepted; the program's newer notices are on this page when there are any.
How much funding is available?
Awards of up to $1.0 million each. About $5.0 million in total for one award.
Who has won Prevention of Disease, Disability, and Death by Infectious Diseases grants before?
The largest recipients over five fiscal years were Puerto Rico Science, Technology, and Research Trust, Massachusetts Department of Public Health, Emory University. The program made 128 awards worth $241 million in that time.
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