Well Told Grants

Grants / Department of Health and Human Services / Centers for Disease Control and Prevention - ERA

RFA-CE-25-028: Effectiveness Research to Prevent Polysubstance-Impaired Driving

Closed Closed December 2, 2024 Opportunity RFA-CE-25-028

This grant is closed. A newer notice from the same program is open now: NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional) (PA-27-100). Status: Due dates in the notice, expires April 5, 2027. It is in our archive of Centers for Disease Control and Prevention - ERA notices from 2024.

Centers for Disease Control and Prevention - ERA offered grants of up to $350,000 to any type of organization. It expected to make one award worth $1.1 million in total. Applications closed on December 2, 2024.

From the official notice on Grants.gov, last changed August 30, 2024. Checked November 7, 2026.

Key dates

PostedAugust 30, 2024
DeadlineDecember 2, 2024
Archived by Grants.govMarch 9, 2025

Who can apply

This opportunity was open to any type of organization.

All 16 applicant types the notice lists

See Section III. Eligibility Information.

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses, individuals.

Is this a realistic fit?

What the grant funds

The Centers for Disease Control and Prevention’s (CDC) National Center for Injury Prevention and Control (NCIPC) is soliciting investigator-initiated research to rigorously evaluate and examine effectiveness of strategies, programs, or policies (collectively referred to as “strategies”) for preventing polysubstance-impaired driving and associated crashes, nonfatal injuries, or deaths. Polysubstance-impaired driving means driving while impaired by two or more substances, such as alcohol and opioids or cannabis and alcohol. Comprehensive evaluations of strategies to prevent polysubstance-impaired driving are lacking and urgently needed given the changing landscape of substance use and impaired driving. Additionally, given inequitable impacts on some populations (American Indian and Alaska Native [AIAN] communities, rural populations, etc.), research is needed to examine strategy effectiveness among different populations. This NOFO supports research that can help fill these gaps. Research may include, but is not limited to, evaluation of the impact of any of the following on preventing polysubstance-impaired driving and related outcomes: 1) Evidence-based alcohol-impaired driving strategies that may also prevent polysubstance-impaired driving. Examples include, but are not limited to, screening and brief intervention and alternative transportation or transit programs. 2) Strategies that prevent excessive alcohol use, harmful substance use, or substance use disorders that have the capacity to also prevent polysubstance-impaired driving. Examples include, but are not limited to, taxation or pricing policies for alcohol and cannabis, social norming campaigns, and multi-component coalition-based strategies (e.g., Drug Free Communities Programs or similar efforts). This NOFO encourages examination of strategy effects on polysubstance-impaired driving and associated injuries and deaths among the overall population and disproportionately affected populations.

Category: Health.

Who has won Injury Prevention and Control Research and State and Community Based Programs grants before

From fiscal 2021 to 2025, Injury Prevention and Control Research and State and Community Based Programs (93.136) awarded $2.2 billion across 986 grant awards, an average of $2.2 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
Florida Department of HealthFlorida12$81.1 million
California Department of Public HealthCalifornia11$55.4 million
Ohio Department of HealthOhio9$42.0 million
North Carolina Department of Health & Human ServicesNorth Carolina12$42.0 million
Michigan Department of Health and Human ServicesMichigan10$37.9 million

Top states: California ($127 million), Pennsylvania ($106 million), Ohio ($105 million), Georgia ($102 million), Florida ($84.6 million).

Applying now

This notice no longer takes applications. Apply under the newer notice, PA-27-100, which is open now.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is RFA-CE-25-028 still open?

No. It closed on December 2, 2024. A newer notice is open: PA-27-100, due dates in the notice, expires April 5, 2027.

Who can apply for Effectiveness Research to Prevent Polysubstance-Impaired Driving?

Centers for Disease Control and Prevention - ERA accepted applications from any type of organization. The notice adds further conditions, so read its eligibility section.

What is the deadline for Effectiveness Research to Prevent Polysubstance-Impaired Driving?

Closed December 2, 2024. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

Awards of up to $350,000 each. About $1.1 million in total for one award.

Who has won Injury Prevention and Control Research and State and Community Based Programs grants before?

The largest recipients over five fiscal years were Florida Department of Health, California Department of Public Health, Ohio Department of Health. The program made 986 awards worth $2.2 billion in that time.

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