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Grants / Department of Health and Human Services / Centers for Disease Control and Prevention - ERA

RFA-CE-23-008: Research Grants to Develop and Validate a Prognostic Tool of Mental Health Sequelae After Traumatic Brain Injury for Adolescent Patients (U01)

Closed Closed January 24, 2023 Opportunity RFA-CE-23-008

This grant is closed. A newer notice from the same program is open now: NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional) (PA-27-100). Status: Due dates in the notice, expires April 5, 2027. It is in our archive of Centers for Disease Control and Prevention - ERA notices from 2022.

Centers for Disease Control and Prevention - ERA offered grants of up to $550,000 to any type of organization. It expected to make about 2 awards worth $5.5 million in total. Applications closed on January 24, 2023.

From the official notice on Grants.gov, last changed November 23, 2022. Checked November 7, 2026.

Key dates

PostedNovember 16, 2022
DeadlineJanuary 24, 2023
Archived by Grants.govFebruary 23, 2023

Who can apply

This opportunity was open to any type of organization.

All 16 applicant types the notice lists

See Section III. Eligibility Information

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses, individuals.

Is this a realistic fit?

What the grant funds

The Centers for Disease Control and Prevention's National Center for Injury Prevention and Control (NCIPC) is soliciting investigator-initiated research proposals to conduct a well-designed, longitudinal study within a large pediatric healthcare system(s) serving a diverse patient population, to derive and validate a new prognostic tool that identifies adolescents (ages 11-17 years) at increased risk for mental health sequelae or a worsening of an existing mental health condition(s). Of particular interest is research that focuses on adolescent populations shown to have higher rates of traumatic brain injury (TBI) incidence or greater risk of negative post-TBI outcomes (e.g., Black and Hispanic youth, youth living in rural areas, and those without insurance). The primary objectives of this NOFO are: Identification of risk/protective factors in the acute care setting that can predict new or worsening mental health sequelae within the three (3) months following a TBI among adolescents (ages 11-17 years Development of a new prognostic tool, based on empirically derived risk/protective factors, that can aid in predicting which adolescents in a clinical setting are more likely to subsequently develop mental health sequelae or experience a worsening of an existing mental health condition(s). Validation of the new empirically derived tool’s ability to accurately predict the development of mental health sequelae or experience a worsening of an existing mental health condition(s). Secondary Outcomes: Secondary outcomes for this project include publications and presentations describing results; new/modified recommendations for pediatric mTBI guideline(s); recommendations related to improving the feasibility of implementing the tool within a healthcare system; development and promotion of communication products related to the prognostic tool; potential development of a module/application based on the prognostic tool that is compatible and interoperable with multiple EHR vendors.

Category: Health.

Who has won Injury Prevention and Control Research and State and Community Based Programs grants before

From fiscal 2021 to 2025, Injury Prevention and Control Research and State and Community Based Programs (93.136) awarded $2.2 billion across 986 grant awards, an average of $2.2 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
Florida Department of HealthFlorida12$81.1 million
California Department of Public HealthCalifornia11$55.4 million
Ohio Department of HealthOhio9$42.0 million
North Carolina Department of Health & Human ServicesNorth Carolina12$42.0 million
Michigan Department of Health and Human ServicesMichigan10$37.9 million

Top states: California ($127 million), Pennsylvania ($106 million), Ohio ($105 million), Georgia ($102 million), Florida ($84.6 million).

Applying now

This notice no longer takes applications. Apply under the newer notice, PA-27-100, which is open now.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is RFA-CE-23-008 still open?

No. It closed on January 24, 2023. A newer notice is open: PA-27-100, due dates in the notice, expires April 5, 2027.

Who can apply for Research Grants to Develop and Validate a Prognostic Tool of Mental Health Sequelae After Traumatic Brain Injury for Adolescent Patients (U01)?

Centers for Disease Control and Prevention - ERA accepted applications from any type of organization. The notice adds further conditions, so read its eligibility section.

What is the deadline for Research Grants to Develop and Validate a Prognostic Tool of Mental Health Sequelae After Traumatic Brain Injury for Adolescent Patients (U01)?

Closed January 24, 2023. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

Awards of up to $550,000 each. About $5.5 million in total across about 2 awards.

Who has won Injury Prevention and Control Research and State and Community Based Programs grants before?

The largest recipients over five fiscal years were Florida Department of Health, California Department of Public Health, Ohio Department of Health. The program made 986 awards worth $2.2 billion in that time.

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