RFA-CE-21-002: Research Grants to Develop or Identify Effective Strategies to Prevent Overdose Involving Illicit Stimulants and Polysubstance Use Involving Stimulants
Closed
This grant is closed. A newer notice from the same program is open now: NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional) (PA-27-100). Status: Due dates in the notice, expires April 5, 2027. It is in our archive of Centers for Disease Control and Prevention - ERA notices from 2021.
Centers for Disease Control and Prevention - ERA offered grants of up to $725,000 to any type of organization. It expected to make about 8 awards worth $13.1 million in total. Applications closed on April 12, 2021.
From the official notice on Grants.gov, last changed March 17, 2021. Checked November 7, 2026.
- Award ceiling$725,000
- Total funding$13.1 million
- Expected awards8
- Cost sharingNot required
- Funding typeGrant
Key dates
| Posted | February 11, 2021 |
|---|---|
| Deadline | April 12, 2021 |
| Archived by Grants.gov | June 30, 2021 |
Who can apply
This opportunity was open to any type of organization.
All 15 applicant types the notice lists
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"
Is this a realistic fit?
- Past Injury Prevention and Control Research and State and Community Based Programs awards averaged $2.2 million; this notice allows up to $725,000 per award.
- Most of the program's money (76% over five years) went to state and local governments.
- No cost sharing or match is required.
What the grant funds
The Centers for Disease Control and Prevention (CDC) National Center for Injury Prevention and Control (NCIPC) is soliciting investigator-initiated research that will support the identification of effective strategies for state, community, or systems-level implementation to prevent fatal and nonfatal overdoses involving illicit stimulants (e.g., methamphetamine and cocaine) as well as polysubstance use and overdose involving illicit stimulants. This Notice of Funding Opportunity (NOFO) is intended to support research on one of the following two Objectives: Objective 1: Conduct a process and outcome evaluation of new or adapted strategies, programs, or policies that can be implemented at the state, community, or systems-level to prevent illicit stimulant use or fatal and nonfatal overdose involving illicit stimulants, or polysubstance use or overdose involving illicit stimulants, ORObjective 2: Assess risk and protective factors for illicit stimulant use, use disorder, and overdose that can contribute to the development or adaptation of intervention strategies.
Who has won Injury Prevention and Control Research and State and Community Based Programs grants before
From fiscal 2021 to 2025, Injury Prevention and Control Research and State and Community Based Programs (93.136) awarded $2.2 billion across 986 grant awards, an average of $2.2 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Florida Department of Health | Florida | 12 | $81.1 million |
| California Department of Public Health | California | 11 | $55.4 million |
| Ohio Department of Health | Ohio | 9 | $42.0 million |
| North Carolina Department of Health & Human Services | North Carolina | 12 | $42.0 million |
| Michigan Department of Health and Human Services | Michigan | 10 | $37.9 million |
Applying now
This notice no longer takes applications. Apply under the newer notice, PA-27-100, which is open now.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is RFA-CE-21-002 still open?
No. It closed on April 12, 2021. A newer notice is open: PA-27-100, due dates in the notice, expires April 5, 2027.
Who can apply for Research Grants to Develop or Identify Effective Strategies to Prevent Overdose Involving Illicit Stimulants and Polysubstance Use Involving Stimulants?
Centers for Disease Control and Prevention - ERA accepted applications from any type of organization.
What is the deadline for Research Grants to Develop or Identify Effective Strategies to Prevent Overdose Involving Illicit Stimulants and Polysubstance Use Involving Stimulants?
Closed April 12, 2021. Applications are no longer accepted; the program's newer notices are on this page when there are any.
How much funding is available?
Awards of up to $725,000 each. About $13.1 million in total across about 8 awards.
Who has won Injury Prevention and Control Research and State and Community Based Programs grants before?
The largest recipients over five fiscal years were Florida Department of Health, California Department of Public Health, Ohio Department of Health. The program made 986 awards worth $2.2 billion in that time.
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