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Grants / Department of Health and Human Services / National Institutes of Health

RFA-CA-22-039: The Early Detection Research Network: Clinical Validation Centers (U01 Clinical Trial Optional)

Closed Closed September 19, 2022 Opportunity RFA-CA-22-039

This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2022.

National Institutes of Health offered grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on September 19, 2022.

From the official notice on Grants.gov, last changed August 19, 2022. Checked November 7, 2026.

About this NIH notice

Projects funded under RFA-CA-22-039 were run by National Cancer Institute (NCI, 2 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.

Application due dates, page limits and budget limits are set in the notice. Read RFA-CA-22-039 in the NIH Guide.

Other notices with this title

National Institutes of Health has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
RFA-CA-22-054August 19, 2022Closed September 19, 2022Closed
RFA-CA-21-033June 1, 2021Closed September 9, 2021Closed

Key dates

PostedJuly 18, 2022
DeadlineSeptember 19, 2022
Archived by Grants.govOctober 19, 2022

Who can apply

This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

All 15 applicant types the notice lists

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses.

Is this a realistic fit?

What the grant funds

The objectives of the Early Detection Research Network (EDRN; edrn.cancer.gov) are to discover, develop and validate biomarkers and imaging methods to detect early stage cancers and to translate these into clinical tests. The EDRN provides an infrastructure that is essential for this process and has successfully completed more than10 multicenter validation studies.

Category: Education, Health.

Funded under RFA-CA-22-039 so far

NIH funded 2 projects under RFA-CA-22-039 in fiscal 2023 to 2026, at 2 institutions. The median yearly award was $1.0 million.

Recently funded projects
ProjectInstitutionFiscal yearAward
DNA evaluation of fragments for early interception (DELFI) of Lung cancer U01Johns Hopkins University2026$1.0 million
MD Anderson Cancer Center EDRN- Clinical Validation Center for Early Detection of Ovarian Cancer with a multiple marker algorithm U01University of TX MD Anderson Can Ctr2026$1.1 million

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Cancer Detection and Diagnosis Research grants before

From fiscal 2021 to 2025, Cancer Detection and Diagnosis Research (93.394) awarded $2.7 billion across 1,944 grant awards, an average of $1.4 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Regents of the University of California, San FranciscoCalifornia56$114 million
Fred Hutchinson Cancer CenterWashington37$96.7 million
The Leland Stanford Junior UniversityCalifornia62$89.1 million
Sloan-Kettering Institute for Cancer ResearchNew York52$88.7 million
The Johns Hopkins UniversityMaryland63$86.5 million

Top states: California ($490 million), New York ($238 million), Massachusetts ($234 million), Pennsylvania ($213 million), Texas ($186 million).

Applying now

This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is RFA-CA-22-039 still open?

No. It closed on September 19, 2022.

Who can apply for The Early Detection Research Network: Clinical Validation Centers (U01 Clinical Trial Optional)?

National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for The Early Detection Research Network: Clinical Validation Centers (U01 Clinical Trial Optional)?

Closed September 19, 2022. Applications are no longer accepted; the program's newer notices are on this page when there are any.

Who has been funded under RFA-CA-22-039?

NIH RePORTER lists 2 projects funded under RFA-CA-22-039 in fiscal 2023 to 2026, at 2 institutions. The most were at Johns Hopkins University, University of TX MD Anderson Can Ctr.

Who has won Cancer Detection and Diagnosis Research grants before?

The largest recipients over five fiscal years were The Regents of the University of California, San Francisco, Fred Hutchinson Cancer Center, The Leland Stanford Junior University. The program made 1,944 awards worth $2.7 billion in that time.

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