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Grants / Department of Health and Human Services / National Institutes of Health

RFA-CA-21-036: SBIR Phase IIB Bridge Awards to Accelerate the Development of Cancer-Relevant Technologies Toward Commercialization (R44 Clinical Trial Optional)

Closed Closed August 6, 2021 Opportunity RFA-CA-21-036

This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2021.

National Institutes of Health offered grants to small businesses. Applications closed on August 6, 2021.

From the official notice on Grants.gov, last changed March 25, 2021. Checked November 7, 2026.

About this NIH notice

Projects funded under RFA-CA-21-036 were run by National Cancer Institute (NCI, 3 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.

Application due dates, page limits and budget limits are set in the notice. Read RFA-CA-21-036 in the NIH Guide.

Other notices with this title

National Institutes of Health has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
RFA-CA-24-022April 23, 2024Closed August 21, 2024Closed
RFA-CA-23-034April 21, 2023Closed August 21, 2023Closed
RFA-CA-22-025April 5, 2022Closed August 5, 2022Closed

Key dates

PostedMarch 25, 2021
DeadlineAugust 6, 2021
Archived by Grants.govSeptember 11, 2021

Who can apply

This opportunity was open to small businesses.

Other Eligible Applicants include the following: Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, may be allowed.

More grants for small businesses.

Is this a realistic fit?

What the grant funds

This Funding Opportunity Announcement (FOA) solicits Small Business Innovation Research (SBIR) applications from small business concerns (SBCs) that seek additional funding to support the next stage of development for cancer-relevant projects that were previously funded under SBIR or STTR Phase II awards from any Federal agency. The purpose of this FOA is to facilitate the transition of SBIR or STTR Phase II projects to the commercialization stage. This FOA is expected to promote partnerships between Federally-funded SBIR or STTR Phase II awardees and third-party investors and/or strategic partners to facilitate and accelerate the capital-intensive steps that are required to commercialize new products and services. Applicants must submit a Commercialization Plan, which should include details on any independent third-party investor funding that has already been secured or is anticipated during the Phase IIB Bridge Award project period. It is expected that the level of this independent third-party funding will be equal to or greater than the NCI funds being requested throughout the Phase IIB Bridge Award project period. Proposed projects may address preclinical and/or clinical stages of technology development. Clinical trials may be proposed as appropriate but are not required.

Category: Education, Health.

Funded under RFA-CA-21-036 so far

NIH funded 3 projects under RFA-CA-21-036 in fiscal 2022 to 2024, at 3 institutions. The median yearly award was $1.3 million.

Recently funded projects
ProjectInstitutionFiscal yearAward
Pivotal Clinical Study of the TruScore Device for Non-Invasive Skin Cancer Diagnostics R44Veriskin, Inc.2024$742,845
Bringing 4π radiation therapy to the clinic R44Celestial Oncology Inc.2024$1.6 million
Development of GPER Agonists as Therapeuticsfor Cutaneous and Uveal Melanoma R44Linnaeus Therapeutics, LLC2023$2.0 million

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Cancer Treatment Research grants before

From fiscal 2021 to 2025, Cancer Treatment Research (93.395) awarded $5.6 billion across 3,622 grant awards, an average of $1.5 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Univeristy of Texas M.D. Anderson Cancer CenterTexas144$188 million
Dana-Farber Cancer Institute, Inc.Massachusetts68$185 million
Icahn School of Medicine at Mount SinaiNew York35$179 million
Public Health InstituteCalifornia4$168 million
Fred Hutchinson Cancer CenterWashington57$156 million

Top states: California ($843 million), New York ($604 million), Massachusetts ($568 million), Texas ($444 million), Pennsylvania ($417 million).

Who has won Cancer Detection and Diagnosis Research grants before

From fiscal 2021 to 2025, Cancer Detection and Diagnosis Research (93.394) awarded $2.7 billion across 1,944 grant awards, an average of $1.4 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Regents of the University of California, San FranciscoCalifornia56$114 million
Fred Hutchinson Cancer CenterWashington37$96.7 million
The Leland Stanford Junior UniversityCalifornia62$89.1 million
Sloan-Kettering Institute for Cancer ResearchNew York52$88.7 million
The Johns Hopkins UniversityMaryland63$86.5 million

Top states: California ($490 million), New York ($238 million), Massachusetts ($234 million), Pennsylvania ($213 million), Texas ($186 million).

Applying now

This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is RFA-CA-21-036 still open?

No. It closed on August 6, 2021.

Who can apply for SBIR Phase IIB Bridge Awards to Accelerate the Development of Cancer-Relevant Technologies Toward Commercialization (R44 Clinical Trial Optional)?

National Institutes of Health accepted applications from small businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for SBIR Phase IIB Bridge Awards to Accelerate the Development of Cancer-Relevant Technologies Toward Commercialization (R44 Clinical Trial Optional)?

Closed August 6, 2021. Applications are no longer accepted; the program's newer notices are on this page when there are any.

Who has been funded under RFA-CA-21-036?

NIH RePORTER lists 3 projects funded under RFA-CA-21-036 in fiscal 2022 to 2024, at 3 institutions. The most were at Veriskin, Inc., Celestial Oncology Inc., Linnaeus Therapeutics, LLC.

Who has won Cancer Detection and Diagnosis Research grants before?

The largest recipients over five fiscal years were The Regents of the University of California, San Francisco, Fred Hutchinson Cancer Center, The Leland Stanford Junior University. The program made 1,944 awards worth $2.7 billion in that time.

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