Well Told Grants

Grants / Department of Health and Human Services / National Institutes of Health

RFA-AT-25-002: Limited Competition: Advancing the Science of Complementary and Integrative Health Approaches to Improve Maternal Health Outcomes (R01 Clinical Trial Required)

Closed Closed May 5, 2025 Opportunity RFA-AT-25-002

This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2025.

National Institutes of Health offered grants of up to $350,000 to colleges and universities. Applications closed on May 5, 2025.

From the official notice on Grants.gov, last changed April 1, 2025. Checked November 7, 2026.

About this NIH notice

Projects funded under RFA-AT-25-002 were run by National Center for Complementary and Integrative Health (NCCIH, 2 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.

Application due dates, page limits and budget limits are set in the notice. Read RFA-AT-25-002 in the NIH Guide.

Key dates

PostedJanuary 8, 2025
DeadlineMay 5, 2025
Archived by Grants.govJune 4, 2025

Who can apply

This opportunity was open to colleges and universities.

Other Eligible Applicants include the following:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. For eligibility criteria details, check the funding opportunity.

More grants for colleges and universities.

Is this a realistic fit?

What the grant funds

This notice of funding opportunity (NOFO) invites investigators currently funded through the NIH Implementing a Maternal Health and Pregnancy Outcomes Vision for Everyone (IMPROVE) Initiative to develop applications to test the feasibility of complementary and integrative approaches with psychological and/or physical inputs (often called mind and body interventions) to promote healthy pregnancies and enhance maternal health outcomes. Currently funded IMPROVE investigators- particularly the Maternal Health Centers of Excellence- are encouraged to partner with investigators with complementary and integrative health expertise. Eligibility is limited to currently funded investigators of the IMPROVE initiative. Applications submitted under this NOFO are expected to propose a multisite feasibility clinical trial that will provide new information that is scientifically necessary for the planning and conduct of a subsequent clinical efficacy or effectiveness study, pragmatic trial, or dissemination and implementation trial on a mind and body intervention to enhance maternal health. It is expected that applications to this NOFO will describe the planned future clinical trial and in so doing demonstrate that the proposed (R01) research is scientifically necessary to design or plan the subsequent fully powered, full-scale clinical trial. Under this R01, the data collected should be used to fill gaps in scientific knowledge, including, but not limited to the following: assessing whether the intervention can be delivered with fidelity across sites; demonstrating feasibility of recruitment, accrual, and randomization of participants across sites; demonstrating participant adherence to the intervention, as well as retention of participants throughout the study across sites; refining and assessing the feasibility of protocolized multimodal interventions, and/or demonstrating feasibility of data collection across sites in preparation for a future fully powered, multisite efficac

Category: Health, Income Security and Social Services.

Funded under RFA-AT-25-002 so far

NIH funded 2 projects under RFA-AT-25-002 in fiscal 2025, at 2 institutions. The median yearly award was $1.4 million.

Recently funded projects
ProjectInstitutionFiscal yearAward
MINDBP - Mindfulness and Wearable Biosensors to Prevent Hypertensive Disorders of Pregnancy R01Medical College of Wisconsin2025$1.3 million
Early Intervention for Postpartum PTSD: Comparing Written Exposure and Capnometry-Guided Breathing Therapy R01Stanford University2025$1.6 million

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Mental Health Research Grants grants before

From fiscal 2021 to 2025, Mental Health Research Grants (93.242) awarded $8.8 billion across 6,785 grant awards, an average of $1.3 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
Yale UnivConnecticut185$371 million
University of Pittsburgh - of the Commonwealth System of Higher EducationPennsylvania200$297 million
University of California, Los AngelesCalifornia176$234 million
Icahn School of Medicine at Mount SinaiNew York144$212 million
The Washington UniversityMissouri149$211 million

Top states: California ($1.4 billion), Massachusetts ($1.1 billion), New York ($1.1 billion), Pennsylvania ($667 million), Connecticut ($422 million).

Who has won Child Health and Human Development Extramural Research grants before

From fiscal 2021 to 2025, Child Health and Human Development Extramural Research (93.865) awarded $6.0 billion across 6,026 grant awards, an average of $1.0 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
Regents of the University of MichiganMichigan167$178 million
The Johns Hopkins UniversityMaryland133$146 million
University of WashingtonWashington114$131 million
Baylor College of MedicineTexas116$124 million
The Leland Stanford Junior UniversityCalifornia104$116 million

Top states: California ($726 million), Massachusetts ($579 million), New York ($456 million), Pennsylvania ($419 million), North Carolina ($365 million).

Who has won Research and Training in Complementary and Integrative Health grants before

From fiscal 2021 to 2025, Research and Training in Complementary and Integrative Health (93.213) awarded $575 million across 653 grant awards, an average of $880,790 per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
Yale UnivConnecticut15$25.9 million
The General Hospital CorporationMassachusetts23$23.1 million
Duke UniversityNorth Carolina11$20.0 million
The Regents of the University of California, San FranciscoCalifornia16$15.2 million
Regents of the University of MinnesotaMinnesota13$15.0 million

Top states: California ($100 million), Massachusetts ($86.8 million), New York ($33.7 million), North Carolina ($30.9 million), Connecticut ($29.9 million).

Applying now

This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is RFA-AT-25-002 still open?

No. It closed on May 5, 2025.

Who can apply for Limited Competition: Advancing the Science of Complementary and Integrative Health Approaches to Improve Maternal Health Outcomes (R01 Clinical Trial Required)?

National Institutes of Health accepted applications from colleges and universities. The notice adds further conditions, so read its eligibility section.

What is the deadline for Limited Competition: Advancing the Science of Complementary and Integrative Health Approaches to Improve Maternal Health Outcomes (R01 Clinical Trial Required)?

Closed May 5, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

Awards of up to $350,000 each.

Who has been funded under RFA-AT-25-002?

NIH RePORTER lists 2 projects funded under RFA-AT-25-002 in fiscal 2025, at 2 institutions. The most were at Medical College of Wisconsin, Stanford University.

Who has won Research and Training in Complementary and Integrative Health grants before?

The largest recipients over five fiscal years were Yale Univ, The General Hospital Corporation, Duke University. The program made 653 awards worth $575 million in that time.

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