Grants / National Science Foundation / U.S. National Science Foundation

NSF PD-20-5345: Engineering of Biomedical Systems

Closed Closed Opportunity NSF PD-20-5345 ☆ Save

This grant is closed. A newer notice from the same program is open now: Major Research Instrumentation Program: (MRI) (NSF 27-500). Status: Closes January 29, 2027 (83 days left). It is in our archive of U.S. National Science Foundation notices from 2025.

• Total funding$10.4 million
• Cost sharingNot required
• Funding typeGrant

Key dates

Who can apply

This opportunity was open to any type of organization.

• Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses, individuals.

Is this a realistic fit?

• Most of the program's money (89% over five years) went to colleges and universities.
• No cost sharing or match is required.

What the grant funds

TheEngineering of Biomedical Systems program is part of the Engineering Biology and Health cluster, which also includes: 1) the Biophotonics program; 2) the Biosensing program; 3) the Cellular and Biochemical Engineering program; and 4) the Disability and Rehabilitation Engineering program. The goal of theEngineering of Biomedical Systems (EBMS) program is to provide opportunities for creating fundamental and transformative research projects that integrate engineering and life sciences to solve biomedical problems and serve humanity in the long term. Projects are expected to use an engineering framework (for example, design or modeling) that supports increased understanding of physiological or pathophysiological processes. Projects must include objectives that advance both engineering and biomedical sciences. Projects may include: methods, models, and enabling tools applied to understand or control living systems; fundamental improvements in deriving information from cells, tissues, organs, and organ systems; or new approaches to the design of systems that include both living and non-living components for eventual medical use in the long term. TheEBMS programsupports fundamental and transformative research in the following areas of biomedical engineering: Developmentof validated models (living or computational) of healthy and pathological tissues and organ systems that can support improved fundamental understanding of these systems or development and testing of medical interventions; Designand validation of systems that integrate living and non-living componentsfor improved understanding, diagnosis, monitoring, and treatment ofdisease or injury; Advancedbiomanufacturing of three-dimensional tissues and organs; Design and subsequent application of technologies andtools, including those that leverage an organism’s microbiome, toinvestigate fundamental physiological and pathophysiological processes;and Application of engineering tools and principles, including mathematical modeling, to quantitatively study the immune system in health and disease and to develop techniques for controlling and modulating a host’s immune response to challenges such as infectious diseases, cancer, implants, autoimmune disorders, wounds, etc. Innovative proposals outside of these specific areas of biomedical engineering may be considered.

Category: Science and Technology and other Research and Development.

Applying now

This notice no longer takes applications. Apply under the newer notice, NSF 27-500, which is open now.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.