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Grants / Department of Health and Human Services / National Institutes of Health

PAR-25-445: NIDCD Clinical Research Center Grant (P50 Clinical Trial Optional)

Closed Closed October 3, 2026 Opportunity PAR-25-445

This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2025.

National Institutes of Health offered grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on October 3, 2026.

From the official notice on Grants.gov, last changed March 31, 2026. Checked November 7, 2026.

About this NIH notice

Application due dates, page limits and budget limits are set in the notice. Read PAR-25-445 in the NIH Guide.

Other notices with this title

National Institutes of Health has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
PAR-22-025October 7, 2021Closed February 7, 2025Closed

Key dates

PostedSeptember 15, 2025
DeadlineOctober 3, 2026
Archived by Grants.govNovember 2, 2026

Who can apply

This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

All 15 applicant types the notice lists

Other Eligible Applicants include the following: Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses.

Is this a realistic fit?

What the grant funds

The National Institute on Deafness and Other Communication Disorders (NIDCD) invites applications for Clinical Research Center Grants designed to advance the diagnosis, prevention, treatment, and amelioration of human sensory and communication disorders. For this announcement, Clinical Research is defined as research involving individuals with a sensory and/or communication disorder, or data/tissues from individuals with a sensory and/or communication disorder. Examples of such research include but are not limited to, studies of the prevention, pathogenesis, pathophysiology, diagnosis, treatment, management or epidemiology of a disease or disorder of hearing, balance, smell, taste, voice, speech, or language. Although the intent is that all the research will involve individuals with sensory and/or communication disorders or data/tissues from individuals with sensory and/or communication disorders, when the clinical research goal(s) warrant(s) limited departures from this intent, alternatives (e.g., non-human research, human subjects without a sensory or communication disorder, human at risk for a sensory and/or communication disorder) are possible with appropriate and strong scientific justification and in consultation with NIDCD staff. Applications may propose a low-risk clinical trial but are not required to (optional).Non-responsive applications will not be reviewed. Prospective applicants are strongly encouraged to read this funding opportunity carefully and communicate with the scientific/research contact listed at the end of this award as early as possible to discuss their application plans.

Category: Health.

Who has won Research Related to Deafness and Communication Disorders grants before

From fiscal 2021 to 2025, Research Related to Deafness and Communication Disorders (93.173) awarded $2.1 billion across 2,231 grant awards, an average of $925,005 per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Johns Hopkins UniversityMaryland73$82.4 million
Massachusetts Eye and Ear InfirmaryMassachusetts41$78.9 million
The University of IowaIowa28$53.4 million
The Leland Stanford Junior UniversityCalifornia39$46.2 million
University of Wisconsin SystemWisconsin56$45.0 million

Top states: Massachusetts ($249 million), California ($247 million), New York ($170 million), Pennsylvania ($125 million), Maryland ($115 million).

Applying now

This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is PAR-25-445 still open?

No. It closed on October 3, 2026.

Who can apply for NIDCD Clinical Research Center Grant (P50 Clinical Trial Optional)?

National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for NIDCD Clinical Research Center Grant (P50 Clinical Trial Optional)?

Closed October 3, 2026. Applications are no longer accepted; the program's newer notices are on this page when there are any.

Who has won Research Related to Deafness and Communication Disorders grants before?

The largest recipients over five fiscal years were The Johns Hopkins University, Massachusetts Eye and Ear Infirmary, The University of Iowa. The program made 2,231 awards worth $2.1 billion in that time.

Similar open grants