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Grants / Department of Health and Human Services / National Institutes of Health

NIH Specialized Center Grant (Parent P50)

Forecast Expected deadline January 11, 2027 Opportunity PA-28-011

National Institutes of Health plans to offer grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. It is a forecast: the notice is expected around November 9, 2026, with applications due around January 11, 2027.

From the official notice on Grants.gov, last changed April 7, 2026. Checked October 31, 2026.

Key dates

Forecast postedApril 7, 2026
Expected postingNovember 9, 2026
Expected deadlineJanuary 11, 2027
Expected award dateOctober 1, 2027

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Who can apply

This opportunity is open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

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Is this a realistic fit?

What the grant funds

Through this Notice of Funding Opportunity (NOFO), the participating NIH Institutes, Centers, and Offices (ICOs) encourage pursuit of the NIH’s mission through the submission of investigator-initiated Specialized Center (P50) applications. With this Parent P50 NOFO, the NIH ICOs intend to support a broadly based, multidisciplinary, often long-term research program with a specific major scientific objective or theme. The proposed Specialized Center must be related to the programmatic interests of one or more of the participating ICOs based on their scientific missions. Applications submitted in response to this NOFO are required to include one administrative core, research projects, and at least one resource core. Inclusion of a Pilot Projects core is optional. The research projects included within the Specialized Center must share a common central scientific theme, focus, and/or an overall objective. Emphasis on how the component research projects build on one another to achieve goals beyond the scope of each individual project is also expected. Specialized Center must demonstrate synergy through cohesiveness, shared resources, and collaborative impact. Statutory authority: Awards are made under the authorization of Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.

Category: Health.

How to apply

  1. Read the full notice and attachments on Grants.gov. The notice is the official source for deadlines and requirements.
  2. Make sure your organization has an active SAM.gov registration and Unique Entity ID; registration can take several weeks.
  3. Register on Grants.gov and submit through Workspace before the deadline and time given in the notice. Our application guide walks through each step.

Questions go to Office of Extramural Activities, niaaaoea@mail.nih.gov, Please contact via e-mail..

Open the official notice

Questions people ask

Who can apply for NIH Specialized Center Grant (Parent P50)?

National Institutes of Health accepts applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for NIH Specialized Center Grant (Parent P50)?

Expected deadline January 11, 2027. Confirm the date and time in the official notice on Grants.gov.

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