PAR-25-308: Small Business Informatics Tools for the Pangenome (R43 Clinical Trial Not Allowed)
Closed
This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2024.
National Institutes of Health offered grants of up to $400,000 to small businesses. Applications closed on March 3, 2025.
From the official notice on Grants.gov, last changed December 10, 2024. Checked November 7, 2026.
- Award ceiling$400,000
- Cost sharingNot required
- Funding typeGrant
About this NIH notice
- Activity codeR43
- Clinical trialsNot allowed
- Funded byNHGRI
- Median yearly award$406,703
- Typical project length1 year
- R43, Small Business Innovation Research (SBIR) Phase I. A small business tests the feasibility of a technology or product. Other open R43 notices.
Projects funded under PAR-25-308 were run by National Human Genome Research Institute (NHGRI, 1 project). Contact the program officer at the institute that fits your project before you apply; the notice lists them.
Application due dates, page limits and budget limits are set in the notice. Read PAR-25-308 in the NIH Guide.
Key dates
| Posted | December 10, 2024 |
|---|---|
| Deadline | March 3, 2025 |
| Archived by Grants.gov | April 8, 2025 |
Who can apply
This opportunity was open to small businesses.
- Small businesses
Other Eligible Applicants include the following: Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, may be allowed.
Is this a realistic fit?
- Projects NIH funded under this notice had a median yearly award of $406,703; it allows up to $400,000 per award.
- Most of the program's money (67% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
This PAR seeks applications from eligible Small Business Concerns (SBCs) for the development of informatics tools with commercial potential to facilitate uptake and scientific use of the human pangenome reference being developed and maintained by the NHGRI Human Genome Reference Program (HGRP). This PAR specifically calls for innovative Phase I SBIR applications from SBCs to demonstrate proof of principle or viability of informatics tools for use of the human pangenome. Emphasis will be on the development of tools to advance compelling use cases that are relevant to different broad sectors of the genomics community, e.g., clinical, population, and functional genomics.
Funded under PAR-25-308 so far
NIH funded 1 project under PAR-25-308 in fiscal 2026, at 1 institution. The median yearly award was $406,703.
| Project | Institution | Fiscal year | Award |
|---|---|---|---|
| Pangenome-based Inference of Phased, Inherited Genome from Patient-Derived Sequencing Data | Cantata Bio LLC | 2026 | $406,703 |
Who has won Human Genome Research grants before
From fiscal 2021 to 2025, Human Genome Research (93.172) awarded $2.2 billion across 1,255 grant awards, an average of $1.7 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| The Leland Stanford Junior University | California | 59 | $153 million |
| University of Washington | Washington | 46 | $123 million |
| The Broad Institute, Inc | Massachusetts | 22 | $119 million |
| University of California Santa Cruz | California | 17 | $64.7 million |
| Baylor College of Medicine | Texas | 24 | $62.9 million |
Applying now
This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is PAR-25-308 still open?
No. It closed on March 3, 2025.
Who can apply for Small Business Informatics Tools for the Pangenome (R43 Clinical Trial Not Allowed)?
National Institutes of Health accepted applications from small businesses. The notice adds further conditions, so read its eligibility section.
What is the deadline for Small Business Informatics Tools for the Pangenome (R43 Clinical Trial Not Allowed)?
Closed March 3, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.
How much funding is available?
Awards of up to $400,000 each.
Who has been funded under PAR-25-308?
NIH RePORTER lists 1 project funded under PAR-25-308 in fiscal 2026, at 1 institution.
Who has won Human Genome Research grants before?
The largest recipients over five fiscal years were The Leland Stanford Junior University, University of Washington, The Broad Institute, Inc. The program made 1,255 awards worth $2.2 billion in that time.
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