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Grants / Department of Health and Human Services / National Institutes of Health

PAR-24-289: Ancillary Studies to Ongoing Clinical Projects (R01 Clinical Trial Not Allowed)

Closed Closed December 5, 2025 Opportunity PAR-24-289

This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2024.

National Institutes of Health offered grants of up to $300,000 to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. It expected to make $300,000 in total. Applications closed on December 5, 2025.

From the official notice on Grants.gov, last changed January 16, 2025. Checked November 7, 2026.

About this NIH notice

Projects funded under PAR-24-289 were run by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS, 8 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.

This notice replaced PAR-23-025.

Application due dates, page limits and budget limits are set in the notice. Read PAR-24-289 in the NIH Guide.

Other notices with this title

National Institutes of Health has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
PAR-23-025November 21, 2022Closed December 8, 2024Closed

Key dates

PostedDecember 9, 2024
DeadlineDecember 5, 2025
Archived by Grants.govJanuary 4, 2026

Who can apply

This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

All 15 applicant types the notice lists

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses.

Is this a realistic fit?

What the grant funds

This Ancillary Studies to Ongoing Clinical Projects (R01 Clinical Trial Not Allowed) PAR, a re-issue of PAR-23-025, was re-issued as a result of the Simplifying Review of Research Project Grant Applications [link: https://grants.nih.gov/policy-and-compliance/policy-topics/peer-review/simplifying-review].The Simplified Review changes in Section V are the only changes that have been made. All other aspects of this funding opportunity remain the same.

For this re-issued notice Grants.gov carries only the note on what changed. The research objectives are in the notice in the NIH Guide, and the projects funded under it are listed below.

Category: Health.

Funded under PAR-24-289 so far

NIH funded 8 projects under PAR-24-289 in fiscal 2026, at 8 institutions. The median yearly award was $433,606.

Recently funded projects
ProjectInstitutionFiscal yearAward
Enhancing Skeletal Muscle Recovery and Mitochondrial Function in Older Cancer Survivors R01University of California Los Angeles2026$401,625
Inflammatory Mechanisms Underlying CPPD and Osteoarthritis: Imaging and Biomarker Approaches R01Brigham and Women's Hospital2026$494,439
Effects of Equol, the most bioactive soy isoflavone, on bone microarchitecture, density, strength and turnover R01University of Pittsburgh at Pittsburgh2026$417,923
Mechanisms of systemic bone loss following fracture R01University of California, San Francisco2026$448,563
Defining Flares in VEXAS Syndrome R01New York University School of Medicine2026$446,173
Biomarkers for Predicting Osteoarthritis Incidence in At-Risk Individuals R01University of Missouri-Columbia2026$456,816
Mechanisms of response to CD19 redirected PluriReceptor NK cells in systemic autoimmunity R01University of Texas HLTH Sci Ctr Houston2026$421,040
Intramuscular fat and endocrine signaling in muscular dystrophy R01University of Florida2026$381,527

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Arthritis, Musculoskeletal and Skin Diseases Research grants before

From fiscal 2021 to 2025, Arthritis, Musculoskeletal and Skin Diseases Research (93.846) awarded $2.6 billion across 2,897 grant awards, an average of $908,766 per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Trustees of the University of PennsylvaniaPennsylvania104$104 million
Brigham & Womens Hospital IncMassachusetts89$95.7 million
The Regents of the University of California, San FranciscoCalifornia84$93.3 million
The Washington UniversityMissouri88$72.4 million
Regents of the University of MichiganMichigan73$68.0 million

Top states: California ($336 million), New York ($317 million), Massachusetts ($310 million), Pennsylvania ($225 million), North Carolina ($118 million).

Applying now

This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is PAR-24-289 still open?

No. It closed on December 5, 2025.

Who can apply for Ancillary Studies to Ongoing Clinical Projects (R01 Clinical Trial Not Allowed)?

National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for Ancillary Studies to Ongoing Clinical Projects (R01 Clinical Trial Not Allowed)?

Closed December 5, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

Awards of up to $300,000 each. About $300,000 in total.

Who has been funded under PAR-24-289?

NIH RePORTER lists 8 projects funded under PAR-24-289 in fiscal 2026, at 8 institutions. The most were at University of California Los Angeles, Brigham and Women's Hospital, University of Pittsburgh at Pittsburgh.

Who has won Arthritis, Musculoskeletal and Skin Diseases Research grants before?

The largest recipients over five fiscal years were The Trustees of the University of Pennsylvania, Brigham & Womens Hospital Inc, The Regents of the University of California, San Francisco. The program made 2,897 awards worth $2.6 billion in that time.

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