PAR-23-111: NIMHD Exploratory/Developmental Research Grant Program (R21 - Clinical Trial Optional)
Closed
This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2023.
National Institutes of Health offered grants of up to $275,000 to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on May 23, 2025.
From the official notice on Grants.gov, last changed May 15, 2025. Checked November 7, 2026.
- Award ceiling$275,000
- Cost sharingNot required
- Funding typeGrant
About this NIH notice
- Activity codeR21
- Clinical trialsOptional
- Funded byNIMHD
- Median yearly award$216,954
- Typical project length2.5 years
- R21, Exploratory/Developmental Research Grant. Early, exploratory ideas that may not have preliminary data yet, usually for up to two years. Other open R21 notices.
Projects funded under PAR-23-111 were run by National Institute on Minority Health and Health Disparities (NIMHD, 39 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.
Application due dates, page limits and budget limits are set in the notice. Read PAR-23-111 in the NIH Guide.
Key dates
| Posted | February 1, 2023 |
|---|---|
| Deadline | May 23, 2025 |
| Archived by Grants.gov | June 22, 2025 |
Who can apply
This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.
All 15 applicant types the notice lists
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Is this a realistic fit?
- Projects NIH funded under this notice had a median yearly award of $216,954; it allows up to $275,000 per award.
- Most of the program's money (78% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
NIMHD invites applications to support short-term exploratory or developmental research projects that have the potential to break new ground in the fields of health disparities and health access for all or extend previous discoveries toward new directions or applications that can directly contribute to improving health access for all and reducing health disparities in the U.S.
Funded under PAR-23-111 so far
NIH funded 39 projects under PAR-23-111 in fiscal 2024 to 2026, at 35 institutions. The median yearly award was $216,954.
Who has won Minority Health and Health Disparities Research grants before
From fiscal 2021 to 2025, Minority Health and Health Disparities Research (93.307) awarded $2.0 billion across 1,237 grant awards, an average of $1.6 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| The Johns Hopkins University | Maryland | 37 | $69.3 million |
| The Trustees of Columbia University in the City of New York | New York | 25 | $59.1 million |
| University of Hawaii | Hawaii | 18 | $52.8 million |
| The Regents of the University of California, San Francisco | California | 24 | $49.5 million |
| The Morehouse School of Medicine, Inc. | Georgia | 4 | $44.1 million |
Applying now
This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is PAR-23-111 still open?
No. It closed on May 23, 2025.
Who can apply for NIMHD Exploratory/Developmental Research Grant Program (R21 - Clinical Trial Optional)?
National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.
What is the deadline for NIMHD Exploratory/Developmental Research Grant Program (R21 - Clinical Trial Optional)?
Closed May 23, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.
How much funding is available?
Awards of up to $275,000 each.
Who has been funded under PAR-23-111?
NIH RePORTER lists 39 projects funded under PAR-23-111 in fiscal 2024 to 2026, at 35 institutions. The most were at Johns Hopkins University, The Pennsylvania State University, Wake Forest University Health Sciences.
Who has won Minority Health and Health Disparities Research grants before?
The largest recipients over five fiscal years were The Johns Hopkins University, The Trustees of Columbia University in the City of New York, University of Hawaii. The program made 1,237 awards worth $2.0 billion in that time.
Similar open grants
- Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R21 Clinical Trials Not Allowed)
- Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)
- Developing novel theory and methods for understanding the genetic architecture of complex human traits (R21 Clinical Trial Not Allowed)
- Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics (R21 Clinical Trial Not Allowed)
- New Approaches for Measuring Brain Changes Across Longer Timespans (R21 Clinical Trial Optional)
- Early-Stage Dissemination and Implementation Research in Communication Disorders (R21 Clinical Trial Optional)