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Grants / Department of Health and Human Services / National Institutes of Health

PAR-23-098: Centers of Excellence in Genomic Science (RM1 Clinical Trial Optional)

Closed Closed June 23, 2025 Opportunity PAR-23-098

This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2023.

National Institutes of Health offered grants of up to $1.5 million to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on June 23, 2025.

From the official notice on Grants.gov, last changed February 27, 2024. Checked November 7, 2026.

About this NIH notice

Projects funded under PAR-23-098 were run by National Human Genome Research Institute (NHGRI, 4 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.

Application due dates, page limits and budget limits are set in the notice. Read PAR-23-098 in the NIH Guide.

Other notices with this title

National Institutes of Health has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
PAR-22-107March 8, 2022Closed November 7, 2022Closed

Key dates

PostedApril 13, 2023
DeadlineJune 23, 2025
Archived by Grants.govJuly 23, 2025

Who can apply

This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

All 15 applicant types the notice lists

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses.

Is this a realistic fit?

What the grant funds

1.The Centers of Excellence in Genomic Science (CEGS) program establishes academic Centers for advanced genome research. Each CEGS award supports a multi-investigator, interdisciplinary team to develop integrated, transformative genomic approaches to address a biomedical problem. A CEGS project will address a critical issue in genomic science, genomic medicine, or computational genomics, proposing a highly innovative solution that would be a major advance. The research will entail substantial risk, balanced by outstanding scientific and management plans and very high potential payoff. A CEGS will focus on the development of novel technological or computational methods for the production or analysis of comprehensive data sets, on a genome-scale biomedical problem, or on other ways to develop and use genomic approaches for understanding biological systems or furthering the application of genomic knowledge, data, and methods towards clinical applications. Each CEGS will nurture genomics by facilitating the interaction of investigators from several disciplines. Along with its scientific goals, CEGS will also expand the pool of genomic scientists and engineers that can use and apply the novel methods, concepts, and knowledge developed by the CEGS by providing education and outreach experiences to scientists at all career levels.

Category: Health.

Funded under PAR-23-098 so far

NIH funded 4 projects under PAR-23-098 in fiscal 2024 to 2026, at 4 institutions. The median yearly award was $5.8 million.

Recently funded projects
ProjectInstitutionFiscal yearAward
Technology to understand genetic variant effects in context RM1University of Washington2026$2.1 million
The Duke Center for Combinatorial Gene Regulation: multigenic control of gene expression in health and disease RM1Duke University2026$9.4 million
Center for Multi-Scale Analysis of the Human Epitranscriptome RM1Weill Medical Coll of Cornell Univ2026$10.0 million
Center for Integrated Cellular Analysis RM1New York Genome Center2025$10.0 million

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Mental Health Research Grants grants before

From fiscal 2021 to 2025, Mental Health Research Grants (93.242) awarded $8.8 billion across 6,785 grant awards, an average of $1.3 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
Yale UnivConnecticut185$371 million
University of Pittsburgh - of the Commonwealth System of Higher EducationPennsylvania200$297 million
University of California, Los AngelesCalifornia176$234 million
Icahn School of Medicine at Mount SinaiNew York144$212 million
The Washington UniversityMissouri149$211 million

Top states: California ($1.4 billion), Massachusetts ($1.1 billion), New York ($1.1 billion), Pennsylvania ($667 million), Connecticut ($422 million).

Who has won Human Genome Research grants before

From fiscal 2021 to 2025, Human Genome Research (93.172) awarded $2.2 billion across 1,255 grant awards, an average of $1.7 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Leland Stanford Junior UniversityCalifornia59$153 million
University of WashingtonWashington46$123 million
The Broad Institute, IncMassachusetts22$119 million
University of California Santa CruzCalifornia17$64.7 million
Baylor College of MedicineTexas24$62.9 million

Top states: California ($470 million), Massachusetts ($350 million), New York ($193 million), Washington ($145 million), North Carolina ($119 million).

Applying now

This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is PAR-23-098 still open?

No. It closed on June 23, 2025.

Who can apply for Centers of Excellence in Genomic Science (RM1 Clinical Trial Optional)?

National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for Centers of Excellence in Genomic Science (RM1 Clinical Trial Optional)?

Closed June 23, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

Awards of up to $1.5 million each.

Who has been funded under PAR-23-098?

NIH RePORTER lists 4 projects funded under PAR-23-098 in fiscal 2024 to 2026, at 4 institutions. The most were at University of Washington, Duke University, Weill Medical Coll of Cornell Univ.

Who has won Human Genome Research grants before?

The largest recipients over five fiscal years were The Leland Stanford Junior University, University of Washington, The Broad Institute, Inc. The program made 1,255 awards worth $2.2 billion in that time.

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