PAR-23-038: Testing Centers for Development of Somatic Cell Genome Editing in Model Organisms (U42) (Clinical Trials Not Allowed)
Closed
This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2022.
National Institutes of Health offered grants of up to $500,000 to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on February 1, 2023.
From the official notice on Grants.gov, last changed November 23, 2022. Checked November 7, 2026.
- Award ceiling$500,000
- Cost sharingNot required
- Funding typeCooperative Agreement
About this NIH notice
- Activity codeU42
- Clinical trialsNot allowed
- Funded byOD
- Median yearly award$491,635
- Typical project length5 years
Projects funded under PAR-23-038 were run by NIH Office of the Director (OD, 4 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.
Application due dates, page limits and budget limits are set in the notice. Read PAR-23-038 in the NIH Guide.
Key dates
| Posted | November 23, 2022 |
|---|---|
| Deadline | February 1, 2023 |
| Archived by Grants.gov | March 9, 2023 |
Who can apply
This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.
All 15 applicant types the notice lists
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Is this a realistic fit?
- Projects NIH funded under this notice had a median yearly award of $491,635; it allows up to $500,000 per award.
- Most of the program's money (80% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
The purpose of this Funding Opportunity Announcement (FOA) is to support Testing Centers for Somatic Cell Genome Editing in specified major mammalian animal model species (rodents, pigs, and non-human primates). Each Center will provide resources and testing services to the growing community developing new genome editing technologies and conducting preclinical testing based upon these technologies for therapeutics of human diseases. The Testing Centers will work with NIH funded investigators to assess the efficacy and safety of in vivo genome editing and delivery technologies, determine genome editing thresholds for specific diseases associated with minimal off-target effects, and ascertain feasibility parameters in a model system. This data will be important in determining if a treatment strategy using a specific set of tools is effective and has an acceptable safety profile, or if the efficacy and specificity of editing should be significantly improved. Even though each Testing Center will work on a limited number of focused projects, it is expected that the program and pipeline(s) developed will maintain multifaceted research activities to build core model systems that can be adjusted as required to accommodate a broad spectrum of diseases as well as provide fee-for-service to the wider biomedical community on a national basis.
Funded under PAR-23-038 so far
NIH funded 4 projects under PAR-23-038 in fiscal 2023 to 2026, at 3 institutions. The median yearly award was $491,635.
| Project | Institution | Fiscal year | Award |
|---|---|---|---|
| Coordination Component | University of California at Davis | 2026 | $94,133 |
| Swine Somatic Cell Gene Editing Testing Center | University of Missouri-Columbia | 2026 | $1.3 million |
| Genome Editing and Biological Effects Testing Section | Baylor College of Medicine | 2026 | $491,635 |
| MU Rodent Testing Center for Somatic Cell Genome Editing | University of Missouri-Columbia | 2025 | $423,027 |
Who has won Research Infrastructure Programs grants before
From fiscal 2021 to 2025, Research Infrastructure Programs (93.351) awarded $1.4 billion across 1,102 grant awards, an average of $1.3 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| University of California, Davis | California | 27 | $102 million |
| Oregon Health & Science University | Oregon | 18 | $92.1 million |
| University of Washington | Washington | 7 | $79.5 million |
| Emory University | Georgia | 14 | $78.3 million |
| The Administrators of Tulane Educational Fund | Louisiana | 10 | $68.0 million |
Applying now
This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is PAR-23-038 still open?
No. It closed on February 1, 2023.
Who can apply for Testing Centers for Development of Somatic Cell Genome Editing in Model Organisms (U42) (Clinical Trials Not Allowed)?
National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.
What is the deadline for Testing Centers for Development of Somatic Cell Genome Editing in Model Organisms (U42) (Clinical Trials Not Allowed)?
Closed February 1, 2023. Applications are no longer accepted; the program's newer notices are on this page when there are any.
How much funding is available?
Awards of up to $500,000 each.
Who has been funded under PAR-23-038?
NIH RePORTER lists 4 projects funded under PAR-23-038 in fiscal 2023 to 2026, at 3 institutions. The most were at University of Missouri-Columbia, University of California at Davis, Baylor College of Medicine.
Who has won Research Infrastructure Programs grants before?
The largest recipients over five fiscal years were University of California, Davis, Oregon Health & Science University, University of Washington. The program made 1,102 awards worth $1.4 billion in that time.
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