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PAR-21-341: Exploratory Grants in Cancer Control (R21 Clinical Trial Optional)

Closed Closed October 8, 2024 Opportunity PAR-21-341

This grant is closed. A newer notice from the same program is open now: Exploratory Grants in Cancer Control (R21 Clinical Trial Optional) (PA-25-253). Status: Due dates in the notice, expires September 7, 2028. It is in our archive of National Institutes of Health notices from 2021.

National Institutes of Health offered grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on October 8, 2024.

From the official notice on Grants.gov, last changed October 12, 2021. Checked November 7, 2026.

About this NIH notice

Projects funded under PAR-21-341 were run by National Cancer Institute (NCI, 20 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.

Application due dates, page limits and budget limits are set in the notice. Read PAR-21-341 in the NIH Guide.

Other notices with this title

National Institutes of Health has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
PA-25-253November 12, 2024Due dates in the notice, expires September 7, 2028Open

Key dates

PostedOctober 12, 2021
DeadlineOctober 8, 2024
Archived by Grants.govNovember 13, 2024

Who can apply

This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

All 15 applicant types the notice lists

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses.

Is this a realistic fit?

What the grant funds

This funding opportunity announcement (FOA) encourages the submission of exploratory/developmental research grant (R21) applications that focus on different aspects of cancer control by modifying behavior, screening, and understanding etiologic factors contributing to the development of cancer, and developing ways to control cancer. The overarching goal is to provide support to promote the early and conceptual stages of research efforts on novel scientific ideas that have the potential to substantially advance population-based cancer research, such as the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of cancer research (epidemiologic, biomedical, behavioral, health care delivery or clinical).

Category: Education, Health.

Funded under PAR-21-341 so far

NIH funded 20 projects under PAR-21-341 in fiscal 2023 to 2026, at 17 institutions. The median yearly award was $238,415.

Most projects: Arizona State University-Tempe Campus (Arizona), 2, Massachusetts General Hospital (Massachusetts), 2, University of South Carolina at Columbia (South Carolina), 2, Washington University (Missouri), 1, Vanderbilt University Medical Center (Tennessee), 1.

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Cancer Cause and Prevention Research grants before

From fiscal 2021 to 2025, Cancer Cause and Prevention Research (93.393) awarded $3.6 billion across 2,517 grant awards, an average of $1.4 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Univeristy of Texas M.D. Anderson Cancer CenterTexas81$107 million
Sloan-Kettering Institute for Cancer ResearchNew York65$99.1 million
The Trustees of Columbia University in the City of New YorkNew York48$85.3 million
Dana-Farber Cancer Institute, Inc.Massachusetts51$83.1 million
University of North Carolina at Chapel HillNorth Carolina49$76.1 million

Top states: California ($465 million), New York ($445 million), Massachusetts ($350 million), Texas ($259 million), Pennsylvania ($175 million).

Who has won Cancer Control grants before

From fiscal 2021 to 2025, Cancer Control (93.399) awarded $814 million across 113 grant awards, an average of $7.2 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
Ecog-Acrin Medical Research Foundation, Inc.Pennsylvania1$87.9 million
NRG Oncology Foundation IncPennsylvania1$54.3 million
Alliance NCTN FoundationIllinois1$50.2 million
Oregon Health & Science UniversityOregon2$34.4 million
University of RochesterNew York1$29.8 million

Top states: Pennsylvania ($157 million), Illinois ($95.2 million), New York ($62.0 million), California ($54.0 million), Wisconsin ($44.3 million).

Applying now

This notice no longer takes applications. Apply under the newer notice, PA-25-253, which is open now.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is PAR-21-341 still open?

No. It closed on October 8, 2024. A newer notice is open: PA-25-253, due dates in the notice, expires September 7, 2028.

Who can apply for Exploratory Grants in Cancer Control (R21 Clinical Trial Optional)?

National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for Exploratory Grants in Cancer Control (R21 Clinical Trial Optional)?

Closed October 8, 2024. Applications are no longer accepted; the program's newer notices are on this page when there are any.

Who has been funded under PAR-21-341?

NIH RePORTER lists 20 projects funded under PAR-21-341 in fiscal 2023 to 2026, at 17 institutions. The most were at Arizona State University-Tempe Campus, Massachusetts General Hospital, University of South Carolina at Columbia.

Who has won Cancer Cause and Prevention Research grants before?

The largest recipients over five fiscal years were The Univeristy of Texas M.D. Anderson Cancer Center, Sloan-Kettering Institute for Cancer Research, The Trustees of Columbia University in the City of New York. The program made 2,517 awards worth $3.6 billion in that time.

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