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Grants / Department of Health and Human Services / National Institutes of Health

PAR-21-264: Computationally-Defined Behaviors in Psychiatry (R21 Clinical Trial Optional)

Closed Closed September 25, 2023 Opportunity PAR-21-264

This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2021.

National Institutes of Health offered grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on September 25, 2023.

From the official notice on Grants.gov, last changed September 25, 2023. Checked November 7, 2026.

About this NIH notice

Projects funded under PAR-21-264 were run by National Institute of Mental Health (NIMH, 3 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.

This notice replaced RFA-MH-19-240.

Application due dates, page limits and budget limits are set in the notice. Read PAR-21-264 in the NIH Guide.

Other notices with this title

National Institutes of Health has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
PAR-23-305September 19, 2023Closed November 1, 2023Closed

Key dates

PostedJuly 7, 2021
DeadlineSeptember 25, 2023
Archived by Grants.govOctober 25, 2023

Who can apply

This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

All 15 applicant types the notice lists

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses.

Is this a realistic fit?

What the grant funds

Reissue of RFA-MH-19-240. This Funding Opportunity Announcement (FOA) solicits proposals for research projects that will apply computational approaches to develop parametrically detailed behavioral assays across mental-health relevant domains of function. These projects should focus on behavior in humans and test computational models in healthy subjects. For future applications, NIMH is particularly interested in behavioral measures, models, and parameters that have the potential for back-translation from humans to animals, especially for pre-clinical therapeutics development. NIMH is also interested in models that can be extended to clinical populations in the future.

For this re-issued notice Grants.gov carries only the note on what changed. The research objectives are in the notice in the NIH Guide, and the projects funded under it are listed below.

Category: Health.

Funded under PAR-21-264 so far

NIH funded 3 projects under PAR-21-264 in fiscal 2022 to 2024, at 3 institutions. The median yearly award was $234,732.

Recently funded projects
ProjectInstitutionFiscal yearAward
Quantifying the cognitive processes supporting computations of stochasticity and volatility in humans R21University of Southern California2024$206,250
Computational dissociation of the causes of cognitive rigidity in depression R21University of Minnesota2023$188,348
Characterizing the cognitive computations underlying spatial navigation R21University of Arizona2023$411,919

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Mental Health Research Grants grants before

From fiscal 2021 to 2025, Mental Health Research Grants (93.242) awarded $8.8 billion across 6,785 grant awards, an average of $1.3 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
Yale UnivConnecticut185$371 million
University of Pittsburgh - of the Commonwealth System of Higher EducationPennsylvania200$297 million
University of California, Los AngelesCalifornia176$234 million
Icahn School of Medicine at Mount SinaiNew York144$212 million
The Washington UniversityMissouri149$211 million

Top states: California ($1.4 billion), Massachusetts ($1.1 billion), New York ($1.1 billion), Pennsylvania ($667 million), Connecticut ($422 million).

Applying now

This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is PAR-21-264 still open?

No. It closed on September 25, 2023.

Who can apply for Computationally-Defined Behaviors in Psychiatry (R21 Clinical Trial Optional)?

National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for Computationally-Defined Behaviors in Psychiatry (R21 Clinical Trial Optional)?

Closed September 25, 2023. Applications are no longer accepted; the program's newer notices are on this page when there are any.

Who has been funded under PAR-21-264?

NIH RePORTER lists 3 projects funded under PAR-21-264 in fiscal 2022 to 2024, at 3 institutions. The most were at University of Southern California, University of Minnesota, University of Arizona.

Who has won Mental Health Research Grants grants before?

The largest recipients over five fiscal years were Yale Univ, University of Pittsburgh - of the Commonwealth System of Higher Education, University of California, Los Angeles. The program made 6,785 awards worth $8.8 billion in that time.

Similar open grants