Well Told Grants

Grants / Department of Health and Human Services / National Institutes of Health

PAR-21-254: Investigator Initiated Research in Computational Genomics and Data Science (R01 Clinical Trial Not Allowed)

Closed Closed January 7, 2025 Opportunity PAR-21-254

This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2021.

National Institutes of Health offered grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on January 7, 2025.

From the official notice on Grants.gov, last changed April 30, 2024. Checked November 7, 2026.

About this NIH notice

Projects funded under PAR-21-254 were run by National Human Genome Research Institute (NHGRI, 22 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.

Application due dates, page limits and budget limits are set in the notice. Read PAR-21-254 in the NIH Guide.

Key dates

PostedJuly 29, 2021
DeadlineJanuary 7, 2025
Archived by Grants.govFebruary 6, 2025

Who can apply

This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

All 15 applicant types the notice lists

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses.

Is this a realistic fit?

What the grant funds

The purpose of this funding opportunity announcement (FOA) is to invite applications for a broad range of research efforts in computational genomics, data science, statistics, and bioinformatics relevant to one or both of basic or clinical genomic science, and broadly applicable to human health and disease. This FOA supports fundamental genomics research developing innovative analytical methodologies and approaches, early-stage development of tools and software, and refinement or hardening of software and tools of high value to the biomedical genomics community. Work supported under this FOA should be enabling for genomics and be generalizable or broadly applicable across diseases and biological systems. All applications should address how the methods would scale to address increasingly larger data sets.

Category: Health.

Funded under PAR-21-254 so far

NIH funded 22 projects under PAR-21-254 in fiscal 2022 to 2026, at 20 institutions. The median yearly award was $571,672.

Most projects: Johns Hopkins University (Maryland), 2, University of California Berkeley (California), 2, University of California, San Francisco (California), 1, University of Arizona (Arizona), 1, Cold Spring Harbor Laboratory (New York), 1.

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Human Genome Research grants before

From fiscal 2021 to 2025, Human Genome Research (93.172) awarded $2.2 billion across 1,255 grant awards, an average of $1.7 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Leland Stanford Junior UniversityCalifornia59$153 million
University of WashingtonWashington46$123 million
The Broad Institute, IncMassachusetts22$119 million
University of California Santa CruzCalifornia17$64.7 million
Baylor College of MedicineTexas24$62.9 million

Top states: California ($470 million), Massachusetts ($350 million), New York ($193 million), Washington ($145 million), North Carolina ($119 million).

Applying now

This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is PAR-21-254 still open?

No. It closed on January 7, 2025.

Who can apply for Investigator Initiated Research in Computational Genomics and Data Science (R01 Clinical Trial Not Allowed)?

National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for Investigator Initiated Research in Computational Genomics and Data Science (R01 Clinical Trial Not Allowed)?

Closed January 7, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.

Who has been funded under PAR-21-254?

NIH RePORTER lists 22 projects funded under PAR-21-254 in fiscal 2022 to 2026, at 20 institutions. The most were at Johns Hopkins University, University of California Berkeley, University of California, San Francisco.

Who has won Human Genome Research grants before?

The largest recipients over five fiscal years were The Leland Stanford Junior University, University of Washington, The Broad Institute, Inc. The program made 1,255 awards worth $2.2 billion in that time.

Similar open grants