PA-24-195: NIH Pathway to Independence Award (Parent K99/R00 Independent Basic Experimental Studies with Humans Required)
Closed
This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2024.
National Institutes of Health offered grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on May 24, 2026.
From the official notice on Grants.gov, last changed April 21, 2026. Checked November 7, 2026.
- Award amountsNot given on Grants.gov
- Cost sharingNot required
- Funding typeGrant
About this NIH notice
- K99, Pathway to Independence Award. A mentored postdoctoral phase that leads into the independent R00 phase. Other open K99 notices.
- R00, Research Transition Award. The independent phase of the K99/R00 Pathway to Independence award. Other open R00 notices.
Projects funded under PA-24-195 were run by National Institute of Mental Health (NIMH, 3 projects) and National Institute on Aging (NIA, 1 project). Contact the program officer at the institute that fits your project before you apply; the notice lists them.
Application due dates, page limits and budget limits are set in the notice. Read PA-24-195 in the NIH Guide.
Key dates
| Posted | April 24, 2024 |
|---|---|
| Deadline | May 24, 2026 |
| Archived by Grants.gov | June 23, 2026 |
Who can apply
This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.
All 15 applicant types the notice lists
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Is this a realistic fit?
- Most of the money in the 13 programs behind this notice (73% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
The purpose of the NIH Pathway to Independence Award (K99/R00) program is to increase and maintain a strong cohort of new and talented, NIH-supported, independent investigators. This program is designed to facilitate a timely transition of outstanding postdoctoral researchers with a research and/or clinical doctorate degree from mentored, postdoctoral research positions to independent, tenure-track or equivalent faculty positions. The program will provide independent NIH research support during this transition in order to help awardees to launch competitive, independent research careers.
Funded under PA-24-195 so far
NIH funded 4 projects under PA-24-195 in fiscal 2025 to 2026, at 4 institutions. The median yearly award was $129,195.
| Project | Institution | Fiscal year | Award |
|---|---|---|---|
| Electrophysiological biomarkers to guide deep brain stimulation treatment in obsessive-compulsive disorder | Massachusetts General Hospital | 2026 | $129,195 |
| Causal Dynamics of Human Amygdala-Prefrontal Circuits during Fear Extinction Learning | Washington University | 2026 | $103,310 |
| Emotion network dysfunction and anxiety in early Alzheimer's disease | Yale University | 2026 | $132,786 |
| Mapping neuroendocrine risk for depression across adolescence | University of Minnesota | 2026 | $118,589 |
Who has won Aging Research grants before
From fiscal 2021 to 2025, Aging Research (93.866) awarded $19 billion across 11,026 grant awards, an average of $1.7 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| The Regents of the University of California, San Francisco | California | 337 | $575 million |
| The Trustees of Columbia University in the City of New York | New York | 242 | $574 million |
| University of Southern California | California | 203 | $572 million |
| The Washington University | Missouri | 210 | $556 million |
| Regents of the University of Michigan | Michigan | 232 | $538 million |
Who has won Extramural Research Programs in the Neurosciences and Neurological Disorders grants before
From fiscal 2021 to 2025, Extramural Research Programs in the Neurosciences and Neurological Disorders (93.853) awarded $9.1 billion across 8,641 grant awards, an average of $1.0 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| The General Hospital Corporation | Massachusetts | 203 | $288 million |
| The Regents of the University of California, San Francisco | California | 248 | $277 million |
| The Johns Hopkins University | Maryland | 230 | $276 million |
| The Trustees of Columbia University in the City of New York | New York | 188 | $226 million |
| Regents of the University of Michigan | Michigan | 179 | $221 million |
Who has won Mental Health Research Grants grants before
From fiscal 2021 to 2025, Mental Health Research Grants (93.242) awarded $8.8 billion across 6,785 grant awards, an average of $1.3 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Yale Univ | Connecticut | 185 | $371 million |
| University of Pittsburgh - of the Commonwealth System of Higher Education | Pennsylvania | 200 | $297 million |
| University of California, Los Angeles | California | 176 | $234 million |
| Icahn School of Medicine at Mount Sinai | New York | 144 | $212 million |
| The Washington University | Missouri | 149 | $211 million |
Other programs behind this notice
- Drug Use and Addiction Research Programs
- Child Health and Human Development Extramural Research
- Trans-NIH Research Support
- Vision Research
- Alcohol Research Programs
- Environmental Health
- Research Related to Deafness and Communication Disorders
- Cancer Research Manpower
- Nursing Research
- Research and Training in Complementary and Integrative Health
Applying now
This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is PA-24-195 still open?
No. It closed on May 24, 2026.
Who can apply for NIH Pathway to Independence Award (Parent K99/R00 Independent Basic Experimental Studies with Humans Required)?
National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.
What is the deadline for NIH Pathway to Independence Award (Parent K99/R00 Independent Basic Experimental Studies with Humans Required)?
Closed May 24, 2026. Applications are no longer accepted; the program's newer notices are on this page when there are any.
Who has been funded under PA-24-195?
NIH RePORTER lists 4 projects funded under PA-24-195 in fiscal 2025 to 2026, at 4 institutions. The most were at Massachusetts General Hospital, Washington University, Yale University.
Who has won Environmental Health grants before?
The largest recipients over five fiscal years were Icahn School of Medicine at Mount Sinai, The Trustees of Columbia University in the City of New York, University of North Carolina at Chapel Hill. The program made 1,980 awards worth $2.1 billion in that time.
Similar open grants
- NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)
- NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Required)
- Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)
- Mentored Career Transition Award (KT1/R00)
- NCI Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed)
- NCI Pathway to Independence Award (K99/R00 Clinical Trial Required)