HT9425-23-BCRP-BTA12: DoD Breast Cancer, Breakthrough Award Levels 1 and 2
Closed
This grant is closed. A newer notice from the same program is open now: DoW Breast Cancer, Clinical Research Extension Award (HT942526BCRPCREA2). Status: Closes November 18, 2026 (11 days left). It is in our archive of Defense Health Agency Contracting Activity - DHACA notices from 2023.
Defense Health Agency Contracting Activity - DHACA offered grants to any type of organization. It expected to make about 14 awards worth $20.9 million in total. Applications closed on April 11, 2023.
From the official notice on Grants.gov, last changed February 6, 2023. Checked November 7, 2026.
- Total funding$20.9 million
- Expected awards14
- Cost sharingNot required
- Funding typeCooperative Agreement, Grant
Other notices with this title
| Notice | Posted | Deadline | Status |
|---|---|---|---|
| HT942525BCRPBTA122 | June 16, 2025 | Closed September 10, 2025 | Closed |
| HT942525BCRPBTA12 | April 22, 2025 | Closed June 27, 2025 | Closed |
| HT942524BCRPBTA122 | June 11, 2024 | Closed September 26, 2024 | Closed |
| HT9425-23-BCRP-BTA12-2 | May 2, 2023 | Closed August 8, 2023 | Closed |
| W81XWH-22-BCRP-BTA12-2 | June 9, 2022 | Closed October 6, 2022 | Closed |
| W81XWH-22-BCRP-BTA12 | March 16, 2022 | Closed May 17, 2022 | Closed |
| W81XWH-21-BCRP-BTA12-2 | April 26, 2021 | Closed September 22, 2021 | Closed |
| W81XWH-21-BCRP-BTA12 | January 6, 2021 | Closed March 25, 2021 | Closed |
Key dates
| Posted | February 6, 2023 |
|---|---|
| Deadline | April 11, 2023 |
| Archived by Grants.gov | May 11, 2023 |
Who can apply
This opportunity was open to any type of organization.
- Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"
Is this a realistic fit?
- Most of the program's money (59% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
The intent of the Breakthrough Award is to support promising research that has high potential to lead to or make breakthroughs in breast cancer. The critical components of this award mechanism are: Impact: Research supported by the Breakthrough Award will have the potential for a major impact and accelerate progress toward ending breast cancer. The impact may be near-term or long-term, but must move beyond a minor advancement and have the potential to lead to a fundamentally new approach that is significantly more effective than interventions already approved or in clinical development. Applications are expected to identify the breast cancer patients or at-risk individuals who would ultimately benefit from the proposed research. Research Scope: The Breakthrough Award is structured with four different funding levels. The levels are designed to support major (but not all) stages of research that will lead to clinical application. Each level has a defined research scope. It is the responsibility of the Principal Investigator (PI) to select the level that aligns with the scope of the proposed research. The funding level should be selected based on the research scope defined in the program announcement, and not on the amount of the budget. The current program announcement discusses the Breakthrough Award Levels 1 and 2. Funding Levels 3 and 4 are available under other program announcements (HT9425-23-BCRP-BTA3 and HT9425-23-BCRP-BTA4, respectively). The PI is strongly encouraged to review the research scope defined under each funding level as described in the corresponding Breakthrough Award program announcement before submitting the pre-application. An application that does not meet the intent of the funding level selected will not be recommended for funding, even if it might meet the intent of a different funding level. The following are general descriptions, although not all-inclusive, of the scope of research projects that would be appropriate to propose under the current program announcement: · Funding Level 1: Innovative, high-risk/high-reward research that is in the earliest stages of idea development or is an untested theory that addresses an important problem. To foster research that yields new avenues of investigation, preliminary data are not required. Proof of concept is the anticipated outcome.
Who has won Military Medical Research and Development grants before
From fiscal 2021 to 2025, Military Medical Research and Development (12.420) awarded $6.9 billion across 5,470 grant awards, an average of $1.3 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. | Maryland | 81 | $546 million |
| The Univeristy of Texas M.D. Anderson Cancer Center | Texas | 139 | $166 million |
| The Johns Hopkins University | Maryland | 157 | $153 million |
| The Regents of the University of California, San Francisco | California | 113 | $147 million |
| Duke University | North Carolina | 86 | $123 million |
Applying now
This notice no longer takes applications. Apply under the newer notice, HT942526BCRPCREA2, which is open now.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is HT9425-23-BCRP-BTA12 still open?
No. It closed on April 11, 2023. A newer notice is open: HT942526BCRPCREA2, closes November 18, 2026 (11 days left).
Who can apply for DoD Breast Cancer, Breakthrough Award Levels 1 and 2?
Defense Health Agency Contracting Activity - DHACA accepted applications from any type of organization.
What is the deadline for DoD Breast Cancer, Breakthrough Award Levels 1 and 2?
Closed April 11, 2023. Applications are no longer accepted; the program's newer notices are on this page when there are any.
How much funding is available?
About $20.9 million in total across about 14 awards.
Who has won Military Medical Research and Development grants before?
The largest recipients over five fiscal years were The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., The Univeristy of Texas M.D. Anderson Cancer Center, The Johns Hopkins University. The program made 5,470 awards worth $6.9 billion in that time.