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Grants / Department of Defense / Defense Health Agency Contracting Activity - DHACA

HT9425-23-BCRP-BTA12-2: DoD Breast Cancer, Breakthrough Award Levels 1 and 2

Closed Closed August 8, 2023 Opportunity HT9425-23-BCRP-BTA12-2

This grant is closed. A newer notice from the same program is open now: DoW Breast Cancer, Clinical Research Extension Award (HT942526BCRPCREA2). Status: Closes November 18, 2026 (11 days left). It is in our archive of Defense Health Agency Contracting Activity - DHACA notices from 2023.

Defense Health Agency Contracting Activity - DHACA offered grants to any type of organization. It expected to make about 7 awards worth $10.3 million in total. Applications closed on August 8, 2023.

From the official notice on Grants.gov, last changed May 2, 2023. Checked November 7, 2026.

Other notices with this title

Defense Health Agency Contracting Activity - DHACA has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
HT942525BCRPBTA122June 16, 2025Closed September 10, 2025Closed
HT942525BCRPBTA12April 22, 2025Closed June 27, 2025Closed
HT942524BCRPBTA122June 11, 2024Closed September 26, 2024Closed
HT9425-23-BCRP-BTA12February 6, 2023Closed April 11, 2023Closed
W81XWH-22-BCRP-BTA12-2June 9, 2022Closed October 6, 2022Closed
W81XWH-22-BCRP-BTA12March 16, 2022Closed May 17, 2022Closed
W81XWH-21-BCRP-BTA12-2April 26, 2021Closed September 22, 2021Closed
W81XWH-21-BCRP-BTA12January 6, 2021Closed March 25, 2021Closed

Key dates

PostedMay 2, 2023
DeadlineAugust 8, 2023
Archived by Grants.govSeptember 7, 2023

Who can apply

This opportunity was open to any type of organization.

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Is this a realistic fit?

What the grant funds

The intent of the Breakthrough Award is to support promising research that has high potential to lead to or make breakthroughs in breast cancer. The critical components of this award mechanism are: Impact: Research supported by the Breakthrough Award will have the potential for a major impact and accelerate progress toward ending breast cancer. The impact may be near-term or long-term, but must move beyond a minor advancement and have the potential to lead to a fundamentally new approach that is significantly more effective than interventions already approved or in clinical development. Applications are expected to identify the breast cancer patients or at-risk individuals who would ultimately benefit from the proposed research. Research Scope: The Breakthrough Award is structured with four different funding levels. The levels are designed to support major (but not all) stages of research that will lead to clinical application. Each level has a defined research scope. It is the responsibility of the Principal Investigator (PI) to select the level that aligns with the scope of the proposed research. The funding level should be selected based on the research scope defined in the program announcement, and not on the amount of the budget. The current program announcement discusses the Breakthrough Award Levels 1 and 2. Funding Levels 3 and 4 are available under other program announcements (HT9425-23-BCRP-BTA3-2 and HT9425-23-BCRP-BTA4-2, respectively). The PI is strongly encouraged to review the research scope defined under each funding level as described in the corresponding Breakthrough Award program announcement before submitting the pre-application. An application that does not meet the intent of the funding level selected will not be recommended for funding, even if it might meet the intent of a different funding level. The following are general descriptions, although not all-inclusive, of the scope of research projects that would be appropriate to propose under the current program announcement: · Funding Level 1: Innovative, high-risk/high-reward research that is in the earliest stages of idea development or is an untested theory that addresses an important problem. To foster research that yields new avenues of investigation, preliminary data are not required. Proof of concept is the anticipated outcome.

Category: Science and Technology and other Research and Development.

Who has won Military Medical Research and Development grants before

From fiscal 2021 to 2025, Military Medical Research and Development (12.420) awarded $6.9 billion across 5,470 grant awards, an average of $1.3 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.Maryland81$546 million
The Univeristy of Texas M.D. Anderson Cancer CenterTexas139$166 million
The Johns Hopkins UniversityMaryland157$153 million
The Regents of the University of California, San FranciscoCalifornia113$147 million
Duke UniversityNorth Carolina86$123 million

Top states: Maryland ($793 million), California ($751 million), Texas ($598 million), Massachusetts ($586 million), New York ($508 million).

Applying now

This notice no longer takes applications. Apply under the newer notice, HT942526BCRPCREA2, which is open now.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is HT9425-23-BCRP-BTA12-2 still open?

No. It closed on August 8, 2023. A newer notice is open: HT942526BCRPCREA2, closes November 18, 2026 (11 days left).

Who can apply for DoD Breast Cancer, Breakthrough Award Levels 1 and 2?

Defense Health Agency Contracting Activity - DHACA accepted applications from any type of organization.

What is the deadline for DoD Breast Cancer, Breakthrough Award Levels 1 and 2?

Closed August 8, 2023. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

About $10.3 million in total across about 7 awards.

Who has won Military Medical Research and Development grants before?

The largest recipients over five fiscal years were The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., The Univeristy of Texas M.D. Anderson Cancer Center, The Johns Hopkins University. The program made 5,470 awards worth $6.9 billion in that time.

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