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Grants / Department of Health and Human Services / Administration for Children and Families - ACYF/CB

HHS-2026-ACF-ACYF-CU-0021: Regional Partnership Grants

Closed Closed August 7, 2026 Opportunity HHS-2026-ACF-ACYF-CU-0021

This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of Administration for Children and Families - ACYF/CB notices from 2026.

Administration for Children and Families - ACYF/CB offered grants of up to $1.0 million (at least $250,000) to nonprofits, state and local governments, tribes and businesses. It expected to make about 8 awards worth $8.0 million in total. Applications closed on August 7, 2026.

From the official notice on Grants.gov, last changed July 8, 2026. Checked November 7, 2026.

Key dates

PostedJuly 8, 2026
DeadlineAugust 7, 2026
Archived by Grants.govSeptember 6, 2026

Who can apply

This opportunity was open to nonprofits, state and local governments, tribes and businesses.

All 9 applicant types the notice lists

Eligible applicants are regional partnerships established by agencies within or across states. They consist of mandatory and optional partners. The mandatory partners are: the state child welfare agency that is responsible for administering the state plan under title IV-B or title IV-E of the Social Security Act, the state agency responsible for administering the substance abuse prevention and treatment block grant provided under the Public Health Service Act title CIC, part B subpart II, and the most appropriate administrative office of the juvenile state court overseeing court proceedings involving families who come to the attention of the court due to child abuse or neglect. Optional partners are; additional state agencies, Indian tribes, tribal organizations, tribal consortia, faith-based and community organizations, public or private agencies, including for-profit organizations. There must be a primary lead applicant, as long as they can monitor program activities or services, funding, and reporting requirements. If an Indian tribe or tribal consortium is the lead applicant for a regional partnership, the Indian tribe is not required to include the state child welfare agency as a partner. If the regional partnership is an Indian tribe or tribal consortium, they may not enter into a collaborative agreement only with tribal child welfare agencies (or a consortium of such agencies). Applications from individuals (including sole proprietorships) and foreign entities are not eligible and will be disqualified from the merit review and funding under this funding opportunity. Faith-based and community organizations that meet the eligibility requirements are eligible for awards under this funding opportunity.

More grants for nonprofits, state and local governments, tribes, businesses.

Is this a realistic fit?

What the grant funds

The Regional Partnership Grant (RPG) Program supports regional partnerships between child welfare, substance abuse treatment and juvenile or state courts. The goal is to support family-centered treatment programs and services for children who are in an out-of-home placement or are at risk of being placed in an out-of-home placement due to caregiver's substance abuse. Projects will also work to expand the scope of evidence-based services for families impacted by substance-use disorders. Projects are required to have regional partnerships with legislatively required partners, including a planning and implementation phase, to provide a cost-sharing match, and report on performance indicators. RPG funds may support family-based, comprehensive, long-term substance-use disorder treatment, including medication-assisted treatment and in-home substance-use disorder treatment and recovery services, as well as early intervention and prevention services, children and family counseling, mental health services, parenting skills training, and the replication of successful models for delivering family-based, comprehensive, long-term substance use disorder treatment services. This project is for one 60-month project period, comprised of five 12-month budget periods. It includes a Planning Phase and an Implementation Phase.

Category: Income Security and Social Services.

Who has won Enhance Safety of Children Affected by Substance Abuse grants before

From fiscal 2021 to 2025, Enhance Safety of Children Affected by Substance Abuse (93.087) awarded $50.3 million across 35 grant awards, an average of $1.4 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
Oklahoma Department of Mental Health and Substance Abuse ServicesOklahoma3$4.6 million
Youth Network CouncilIllinois3$3.7 million
Helen Ross McNabb Center, Inc.Tennessee2$3.1 million
Mountain Comprehensive Care Center, Inc.Kentucky2$2.9 million
Meta House, Inc.Wisconsin2$2.9 million

Top states: Illinois ($5.9 million), Tennessee ($5.6 million), Iowa ($5.2 million), Missouri ($4.7 million), Oklahoma ($4.6 million).

Applying now

This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is HHS-2026-ACF-ACYF-CU-0021 still open?

No. It closed on August 7, 2026.

Who can apply for Regional Partnership Grants?

Administration for Children and Families - ACYF/CB accepted applications from nonprofits, state and local governments, tribes and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for Regional Partnership Grants?

Closed August 7, 2026. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

Awards of up to $1.0 million each. About $8.0 million in total across about 8 awards.

Who has won Enhance Safety of Children Affected by Substance Abuse grants before?

The largest recipients over five fiscal years were Oklahoma Department of Mental Health and Substance Abuse Services, Youth Network Council, Helen Ross McNabb Center, Inc. The program made 35 awards worth $50.3 million in that time.

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