Grants for nonprofits in South Carolina
Federal agencies awarded $1.8 billion in 928 grants to nonprofits in South Carolina from fiscal 2021 to 2025. The largest source was Head Start. 856 federal grant opportunities are open or forecast now for nonprofits.
- South Carolina ranks 29th of the 50 states and DC for federal grants to nonprofits.
- Grants to nonprofits made up 3% of all federal grant money to recipients in South Carolina.
- That is 1% of all federal grant money to nonprofits nationwide.
- Awarded, FY 2021 to 2025$1.8 billion
- Grant awards928
- Open now nationwide856
Federal programs that fund nonprofits in South Carolina
| Program | Awarded to nonprofits in South Carolina |
|---|---|
| Head Start | $577 million |
| Affordable Rural Cooperative | $442 million |
| Education Stabilization Fund | $82.7 million |
| VA Supportive Services for Veteran Families Program | $52.4 million |
| Air Force Defense Research Sciences Program | $40.1 million |
| Integrated Ocean Observing System (IOOS) | $38.5 million |
| Inflation Reduction Act Landscape Scale Restoration | $33.6 million |
| Regional Fishery Management Councils | $24.4 million |
| Maternal, Infant and Early Childhood Home Visiting Grant | $20.0 million |
| Teenage Pregnancy Prevention Program | $18.2 million |
Nonprofits in South Carolina that received the most
| Recipient | Awards | Amount |
|---|---|---|
| Central Electric Power Cooperative Inc | 2 | $442 million |
Open federal grants nonprofits can apply for
- Small Business Transportation Technical Assistance Center (Region 1)
Open Closes today - Small Business Transportation Technical Assistance Center (Region 3)
Open Closes today - Region 4 Small Business Transportation Technical Assistance Center (SBTTAC)
Open Closes today - Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61 Clinical Trial Required)
Open Closes November 2, 2026 (2 days left) - Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowed)
Open Closes November 2, 2026 (2 days left) - National Indian Health Outreach and Education
Open Closes November 2, 2026 (2 days left) - BJA FY 2026 Comprehensive Opioid, Stimulant, and Substance Use Program (COSSUP) Training and Technical Assistance (TTA)
Open Closes November 2, 2026 (2 days left) - BJA FY 2026 Upholding the Rule of Law and Preventing Wrongful Convictions Program
Open Closes November 2, 2026 (2 days left) - OJJDP FY 2026 Second Chance Act Youth Reentry Program
Open Closes November 2, 2026 (2 days left) - OJJDP FY 2026 Internet Crimes Against Children (ICAC) Task Force Program Support
Open Closes November 2, 2026 (2 days left) - Topology
Open Closes November 3, 2026 (3 days left) - Geometric Analysis
Open Closes November 3, 2026 (3 days left) - DoW Reconstructive Transplant, Concept Award
Open Closes November 4, 2026 (4 days left) - DoW Bone Marrow Failure, Idea Development Award
Open Closes November 4, 2026 (4 days left) - DoW Bone Marrow Failure, Investigator-Initiated Research Award
Open Closes November 4, 2026 (4 days left) - DoW Bone Marrow Failure, Resource Development Award
Open Closes November 4, 2026 (4 days left) - DoW Reconstructive Transplant, Investigator-Initiated Research Award
Open Closes November 4, 2026 (4 days left) - Exploring and Enhancing Outdoor and Heritage Tourism in the Chesapeake Bay Watershed
Open Closes November 4, 2026 (4 days left) - Developing novel theory and methods for understanding the genetic architecture of complex human traits (R01 Clinical Trial Not Allowed)
Open Closes November 5, 2026 (5 days left) - Emerging Infections Network - Research for Preventing, Detecting, and Managing Travel-associated Infectious Diseases
Open Closes November 5, 2026 (5 days left) - US Travelers Health Research, Surveillance, Communication, and Outreach Network
Open Closes November 5, 2026 (5 days left) - Request for Information - Gauging Investor Interest in the Development and Commercialization of Subsurface Energy Technologies
Open Closes November 5, 2026 (5 days left) - Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R01 Clinical Trial Not Allowed)
Open Closes November 6, 2026 (6 days left) - DoW Parkinson’s, Early Investigator Research Award
Open Closes November 6, 2026 (6 days left) - DoW Parkinson’s, Investigator-Initiated Research Award
Open Closes November 6, 2026 (6 days left)
See all 856 open grants for nonprofits