Federal grants to Sanford Burnham Prebys Medical Discovery Institute
Sanford Burnham Prebys Medical Discovery Institute in La Jolla, California received $270 million in federal grants from fiscal 2021 to 2025, across 141 awards. Its largest program was Aging Research, with $56.9 million. In fiscal 2025 it was awarded $43.2 million.
From USAspending.gov award records, updated November 7, 2026.
- Grants, FY 2021 to 2025$270 million
- Awards141
- Awarded in FY 2025$43.2 million
- Largest award$21.1 million
By year
| Fiscal year | Awards | Amount |
|---|---|---|
| FY 2021 | 71 | $48.9 million |
| FY 2022 | 83 | $67.1 million |
| FY 2023 | 67 | $56.2 million |
| FY 2024 | 64 | $54.6 million |
| FY 2025 | 54 | $43.2 million |
Programs that fund Sanford Burnham Prebys Medical Discovery Institute
| Program | Awards | Amount |
|---|---|---|
| Aging Research | 30 | $56.9 million |
| Drug Use and Addiction Research Programs | 5 | $32.3 million |
| Cardiovascular Diseases Research | 11 | $25.9 million |
| Cancer Biology Research | 14 | $23.1 million |
| Cancer Centers Support Grants | 1 | $21.1 million |
| Trans-NIH Research Support | 4 | $18.0 million |
| Diabetes, Digestive, and Kidney Diseases Extramural Research | 8 | $14.3 million |
| Cancer Treatment Research | 11 | $13.0 million |
| Allergy and Infectious Diseases Research | 8 | $11.4 million |
| Military Medical Research and Development | 13 | $11.3 million |
Awarding agencies
| Agency | Awards | Amount |
|---|---|---|
| Department of Health and Human Services | 126 | $253 million |
| Department of Defense | 14 | $15.9 million |
| National Aeronautics and Space Administration | 1 | $1.3 million |
Largest awards
| Award | Program | First action | Amount |
|---|---|---|---|
| Cancer center support grant | Cancer Centers Support Grants | October 22, 2020 | $21.1 million |
| Protein glycosylation in the coagulopathy and inflammation of sepsis | Cardiovascular Diseases Research | August 20, 2021 | $13.4 million |
| Aging as a risk factor and target for prevention of liver cancer - project summary – overall the incidences of liver cancer (primarily hepatocellular carcinoma (HCC)) are increasing and disease outcome is poor. Consequently, there is an urgent need for new therapies and better preventive strategies. | Aging Research | September 14, 2021 | $12.8 million |
| Spatial mapping senescent cells across the mouse lifespan by multiplex transcriptomics and epigenomics - project summary cellular senescence, characterized by stable proliferation arrest and secretion of pro-inflammatory factors, is not only a hallmark of aging, but also a key contributor to age-ass | Trans-NIH Research Support | July 28, 2022 | $10.8 million |
| Safety/toxicology, adme and cmc activities to support the assessment of the MGLU2 pam SBP-9330 in a phase 2 clinical study in smokers - project summary this resubmission application, “safety/toxicology, adme and cmc activities to support the assessment of the MGLU2 pam SBP-9330 in a phase 2 clinical | Drug Use and Addiction Research Programs | September 18, 2023 | $9.0 million |
| Clinical development of an MGLU2 positive allosteric modulator to treat nicotine addiction | Drug Use and Addiction Research Programs | July 15, 2021 | $7.7 million |
| Characterization, optimization, and development of dual MGLU2/3 positive allosteric modulators for opioid use disorder - project summary opioid use disorder (OUD) is a significant problem worldwide and a surge in methamphetamine (MA) use has emerged in chronic opioid users. Given recent increases in | Drug Use and Addiction Research Programs | July 7, 2022 | $6.4 million |
| Development of SBI-553, an allosteric modulator of NTR1, for the treatment of substance use disorders - project summary opioid use disorder (OUD) is a major public health crisis in the united states, with >50,000 overdose deaths in 2017 alone. Addiction to opioids is intimately related to the physio | Drug Use and Addiction Research Programs | September 8, 2023 | $6.4 million |
| Role of hypernutrition and metabolic stress in non-alcoholic steatohepatitis (NASH) driven hepatocellular carcinoma (HCC) - project summary – overall hepatocellular carcinoma (HCC) is the most common primary liver cancer and a rising cause of cancer mortality. Hcc related to metabolic stress is on t | Cancer Biology Research | September 9, 2024 | $4.7 million |
| Enhancement of a predictive toxicology toolbox via multi-parametric data informed qsar modeling of benchmark toxins | Air Force Defense Research Sciences Program | December 15, 2020 | $4.7 million |
Questions people ask
How much federal grant money does Sanford Burnham Prebys Medical Discovery Institute get?
$270 million in 141 grant awards from fiscal 2021 to 2025, as obligations reported to USAspending.gov.
Which agency gives Sanford Burnham Prebys Medical Discovery Institute the most?
The Department of Health and Human Services, with $253 million in 126 awards. The Department of Defense and the National Aeronautics and Space Administration follow.
What is Sanford Burnham Prebys Medical Discovery Institute's largest federal grant?
$21.1 million under Cancer Centers Support Grants, with its first action in the period on October 22, 2020. That counts only the money obligated in fiscal 2021 to 2025.
Which federal programs fund Sanford Burnham Prebys Medical Discovery Institute?
Its largest are Aging Research, Drug Use and Addiction Research Programs and Cardiovascular Diseases Research.
Other grant recipients in La Jolla
- University of California, San Diego
- The Scripps Research Institute
- University of California San Diego
- The Salk Institute for Biological Studies, San Diego, California
- La Jolla Institute for Immunology
- J. Craig Venter Institute, Inc.
- Proteogenomics Research Institute for Systems Medicine
- Theiss Research
Largest federal grant recipients in California · Federal grants in California