Federal grant programs / Department of Health and Human Services

Health Systems Strengthening and HIV/AIDS Prevention, Care and Treatment under the President's Emergency Plan for AIDS Relief (93.266)

Also known as Office of Global Health

• Awarded, FY 2021 to 2025$129 million
• Grant awards16
• Typical award$1.7 million
• Awarded in FY 2025$14.7 million
• Size rank731 of 1,823
• Type of assistanceCooperative agreements

Key findings

• Annual funding fell from $29.4 million in fiscal 2021 to $14.7 million in fiscal 2025.
• It is the 731st largest of 1,823 federal grant programs by five-year awards.
• The 8 largest recipients received 100% of the money.
• Awards went to recipients in 6 states and territories.

What the program funds

This program supports the development and strengthening of the health workforce and health care delivery systems in countries supported by the President’s Emergency Plan for AIDS Relief (PEPFAR). Consistent with the agency’s statutory role in workforce development, education, training, and technical assistance, program activities focus on building local capacity, integrating health services into routine care, and strengthening systems that enable host country governments to manage and sustain U.S.-supported health programs. These efforts advance the America First Global Health Strategy by promoting country ownership, sustainability, and alignment with U.S. strategic and national security priorities. Objectives include: (1) Strengthen health care delivery systems by expanding access to quality services through workforce support, integrated care, and appropriate health technologies. (2) Support international partnerships that improve population health programs and integrate them into routine health service delivery. (3) Advance U.S. strategic and national security priorities by reducing preventable disease, disability, and death in the United States and globally. Health Systems Strengthening Programs funded through cooperative agreements: (1) Leveraging Health Service Approaches for Sustainable HIV Epidemic Control; (2) Global Reach II; (3) Quality Improvement Solutions for Sustained Epidemic Control; (4) Capacity Building for Sustainable HIV Services. Non-Competing Continuations for FY25: (1) Leveraging Health Service Approaches for Sustainable HIV Epidemic Control (HSEA): $8,000,000? Supports HRSA’s statutory role in strengthening health workforce capacity and health care delivery systems by improving access to quality HIV services. Activities use timely data, appropriate technology, and service delivery improvements to strengthen routine health systems, expand workforce capacity, and support sustainable population health outcomes in PEPFAR-supported countries. (2) Global Reach II (GRII): $3,750,948 Advances HIV epidemic control by strengthening treatment delivery within national and regional health systems. The program focuses on workforce support, service integration, and system management to improve continuity of care and support country-led program implementation. (3) Quality Improvement Solutions for Sustained Epidemic Control Project (QISSEC): $2,684,125 Supports continuous quality improvement across the HIV care continuum. Activities strengthen provider skills, improve service delivery processes, and enhance patient outcomes while reinforcing routine health system functions. (4) Capacity Building for Sustainable HIV Services – Global (CBP): $11,563,395 Builds workforce and health system capacity through education, training, and technical assistance. The program applies proven U.S. practices to strengthen service delivery, improve patient outcomes, and support the transition of U.S.-supported HIV services to host country governments. Competing planned for FY26: Global Reach III (GRIII). (FY26 Funding TBD) Will support AFGHS priorities by strengthening the health workforce, integrating HIV services into routine care, and promoting practical service delivery models. The program will focus on sustainability, country ownership, and improved health outcomes in alignment with U.S. strategic and national security priorities.

From the federal Assistance Listing. Read the full listing on SAM.gov.

Open opportunities

No opportunity under this program is open or forecast on Grants.gov right now. Programs often post once a year, so the funding history below shows what to expect.

Rules from the program listing

Who can apply

Eligibility varies depending on the specific program. Applicants should review the individual HRSA notice of funding opportunity issued under this assistance listing for specific eligibility requirements.

What the money can and cannot pay for

Cooperative Agreements will be awarded to organizations that execute one or more of the objectives above.

Matching requirements

This program has no statutory formula. Matching requirements are not applicable to this assistance listing. MOE requirements are not applicable to this assistance listing.

Deadlines

Contact the headquarters or regional location, as appropriate for application deadlines

Award range and average, in the agency's words

ANNUALLY: Quality Improvement Solutions for Sustained Epidemic Control Project (QISSEC) - $1,000,000 to $20,000,000; Capacity Building for Sustainable HIV Services – Global (CBP)$1,000,000 to $50,000,000; Global Reach II – 1,000,000 to 20,000,000; Leveraging health service equity approaches for sustainable HIV epidemic control (HSEA): $1,000,000 - $10,000,000.

Examples of funded projects

Fiscal Year2022: FY22 Health Systems Strengthening Programs: (1) Quality Improvement Solutions for Sustained Epidemic Control Project, QISSEC(CoAg) (2) Capacity Building for Sustainable HIV Services Project, CBP (CoAg) (3) Global Reach II, GRII (CoAg) (4) Community-Led Monitoring in Sierra Leone, CLM-SL (CoAg). (5) Resilient and Responsive Health Systems Initiative, RRHS (CoAg) (6) Resilient and Responsive Health Organizations Initiative: Sustainability Communities of Practice Initiative, RRHO (CoAg) (7) Health Workforce for HIV and Chronic Disease Service Delivery Global Initiative, HW21 (CoAg) (8) Optimizing Momentum Toward Sustainable Epidemic Control, OpCon (CoAg) FY 22 Actual: $34,836,495.00 (Estimated: $49,913,331 includes ARPA and carryover) FY 22 Range: $125,000.00 - $12,697,356.00 FY 22 Average Award: $657,292.36Fiscal Year2025: Program funds may be used to: (1) Strengthen health systems through training by supporting education and on-the-job learning that help health workers and managers deliver quality services and manage programs effectively. (2) Build practical partnerships with governments, the private sector, and community organizations to improve service delivery and support sustainable health programs. (3) Expand simple, effective service delivery models that integrate health services, improve population health, and help prevent diseases from spreading to the United States.

Quoted from the program's federal Assistance Listing. The notice of funding opportunity is the official source for each competition's rules.

Who usually wins

Colleges and universities received 2.5% of the money.

By state

Each state below has its own page for this program, with its recipients and yearly totals.

Award amounts are federal obligations reported to USAspending.gov for fiscal 2021 to 2025; see how our data works.