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Grants / Department of Defense / Defense Health Agency Contracting Activity - DHACA

W81XWH-22-TERP-IIRA: DOD Toxic Exposures, Investigator-Initiated Research Award

Closed Closed December 1, 2022 Opportunity W81XWH-22-TERP-IIRA

This grant is closed. A newer notice from the same program is open now: DoW Breast Cancer, Clinical Research Extension Award (HT942526BCRPCREA2). Status: Closes November 18, 2026 (11 days left). It is in our archive of Defense Health Agency Contracting Activity - DHACA notices from 2022.

Defense Health Agency Contracting Activity - DHACA offered grants to any type of organization. It expected to make about 12 awards worth $9.6 million in total. Applications closed on December 1, 2022.

From the official notice on Grants.gov, last changed September 21, 2022. Checked November 7, 2026.

Other notices with this title

Defense Health Agency Contracting Activity - DHACA has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
HT942525TERPIIRAJune 5, 2025Closed October 16, 2025Closed
HT9425-23-TERP-IIRAJuly 7, 2023Closed October 4, 2023Closed

Key dates

PostedSeptember 21, 2022
DeadlineDecember 1, 2022
Archived by Grants.govDecember 31, 2022

Who can apply

This opportunity was open to any type of organization.

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Is this a realistic fit?

What the grant funds

The FY22 TERP IIRA is intended to support studies that will make an important contribution toward research and/or patient care for a disease or condition related to toxic exposures. Research projects may focus on any phase of research from basic laboratory research through translational research, including preclinical studies in animal models and human subjects, as well as correlative studies associated with an existing clinical trial. New Approach Methodologies may also be used. Impact: The application should explicitly state how the proposed research will have a significant impact on toxic exposure research and/or patient care with the intent to transition outcomes into clinical practice for Service Members, Veterans, and/or the American public who have been, or could potentially be, impacted by toxic exposures. State both the short- and long-term impacts and how the proposed research will ultimately lead to new treatments/therapeutics, diagnostic assays, or prevention strategies to improve the quality of life for those that have been impacted by, or are likely to encounter, toxic substances. Applications should clearly demonstrate the project’s potential near-term and long-term outcome(s)/product(s) (intellectual knowledge and/or tangible materiel) and how they will impact a critical problem or question in the field of research and/or patient care in at least one of the FY22 TERP Program Goals and at least one of the FY22 TERP Topic Areas addressed. Preliminary data are required. The rationale for a research idea may be derived from laboratory discovery, population-based studies, a clinician’s firsthand knowledge of patients, or anecdotal data. Applications must include relevant preliminary data that support the rationale for the proposed study. These data may be unpublished or from published literature. Proposed research may be related to diseases, conditions, or symptoms supported by other CDMRP programs; however, TERP applications must be relevant to toxic exposures and be responsive to the FY22 TERP Program Goals and Topic Areas.

Category: Science and Technology and other Research and Development.

Who has won Military Medical Research and Development grants before

From fiscal 2021 to 2025, Military Medical Research and Development (12.420) awarded $6.9 billion across 5,470 grant awards, an average of $1.3 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.Maryland81$546 million
The Univeristy of Texas M.D. Anderson Cancer CenterTexas139$166 million
The Johns Hopkins UniversityMaryland157$153 million
The Regents of the University of California, San FranciscoCalifornia113$147 million
Duke UniversityNorth Carolina86$123 million

Top states: Maryland ($793 million), California ($751 million), Texas ($598 million), Massachusetts ($586 million), New York ($508 million).

Applying now

This notice no longer takes applications. Apply under the newer notice, HT942526BCRPCREA2, which is open now.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is W81XWH-22-TERP-IIRA still open?

No. It closed on December 1, 2022. A newer notice is open: HT942526BCRPCREA2, closes November 18, 2026 (11 days left).

Who can apply for DOD Toxic Exposures, Investigator-Initiated Research Award?

Defense Health Agency Contracting Activity - DHACA accepted applications from any type of organization.

What is the deadline for DOD Toxic Exposures, Investigator-Initiated Research Award?

Closed December 1, 2022. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

About $9.6 million in total across about 12 awards.

Who has won Military Medical Research and Development grants before?

The largest recipients over five fiscal years were The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., The Univeristy of Texas M.D. Anderson Cancer Center, The Johns Hopkins University. The program made 5,470 awards worth $6.9 billion in that time.

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