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Grants / Department of Defense / Defense Health Agency Contracting Activity - DHACA

W81XWH-21-TBIPHRP-IIRA: DoD Traumatic Brain Injury and Psychological Health, Investigator-Initiated Research Award

Closed Closed October 7, 2021 Opportunity W81XWH-21-TBIPHRP-IIRA

This grant is closed. A newer notice from the same program is open now: DoW Breast Cancer, Clinical Research Extension Award (HT942526BCRPCREA2). Status: Closes November 18, 2026 (11 days left). It is in our archive of Defense Health Agency Contracting Activity - DHACA notices from 2021.

Defense Health Agency Contracting Activity - DHACA offered grants to any type of organization. It expected to make about 15 awards worth $11.3 million in total. Applications closed on October 7, 2021.

From the official notice on Grants.gov, last changed September 1, 2021. Checked November 7, 2026.

Other notices with this title

Defense Health Agency Contracting Activity - DHACA has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
HT9425-23-TBIPHRP-IIRAApril 27, 2023Closed July 6, 2023Closed
W81XWH-22-TBIPHRP-IIRAJuly 15, 2022Closed September 14, 2022Closed

Key dates

PostedAugust 6, 2021
DeadlineOctober 7, 2021
Archived by Grants.govNovember 6, 2021

Who can apply

This opportunity was open to any type of organization.

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Is this a realistic fit?

What the grant funds

The FY21 TBIPHRP IIRA is intended to support studies that will make an important contribution toward understanding, preventing, and treating TBI and/or psychological health conditions. Research projects may focus on any phase of research from basic laboratory research through translational research, including preclinical studies in animal models and human subjects, as well as correlative studies associated with an existing clinical trial. Research involving human subjects and human anatomical substances is permitted; however, this FY21 TBIPHRP IIRA may not be used to conduct clinical trials. The IIRA is designed to support research with the potential to yield highly impactful discoveries or major advancements. The application should clearly demonstrate the project’s potential near-term and long-term outcome(s)/product(s) (knowledge and/or materiel) and how they will impact a critical problem or question in the field of research and/or patient care in the FY21 TBIPHRP IIRA Focus Areas(s) addressed. A clinical trial is defined as a research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include placebo or other control) to evaluate the effects of the interventions on biomedical or behavioral health-related outcomes. This award may not be used to conduct clinical trials. Applications proposing clinical trials may be submitted to the following FY21 TBIPHRP funding opportunities:  Clinical Trial Award (Funding Opportunity Number: W81XWH-21-S-TBIPH1)  Focused Program Award (Funding Opportunity Number: W81XWH-21-S-TBIPH2)  Translational Research Award (Funding Opportunity Number: W81XWH-21-TBIPHRP-TRA) Clinical research is defined as: (1) patient-oriented research. Research conducted with human subjects (or on material of human origin such as tissues, specimens, and cognitive phenomena) for which an investigator (or colleague) directly interacts with human subjects. Excluded from this definition are in vitro studies that utilize human tissues that cannot be linked to a living individual. Patient-oriented research includes: (a) mechanisms of human disease, (b) therapeutic interventions, (c) clinical trials, and (d) development of new technologies; (2) epidemiologic and behavioral studies; and (3) outcomes research and health services research. Note: Studies that meet the requirements for Institutional Review Board (IRB) Exemption 4 are not considered CDMRP-defined clinical research.

Category: Science and Technology and other Research and Development.

Who has won Military Medical Research and Development grants before

From fiscal 2021 to 2025, Military Medical Research and Development (12.420) awarded $6.9 billion across 5,470 grant awards, an average of $1.3 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.Maryland81$546 million
The Univeristy of Texas M.D. Anderson Cancer CenterTexas139$166 million
The Johns Hopkins UniversityMaryland157$153 million
The Regents of the University of California, San FranciscoCalifornia113$147 million
Duke UniversityNorth Carolina86$123 million

Top states: Maryland ($793 million), California ($751 million), Texas ($598 million), Massachusetts ($586 million), New York ($508 million).

Applying now

This notice no longer takes applications. Apply under the newer notice, HT942526BCRPCREA2, which is open now.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is W81XWH-21-TBIPHRP-IIRA still open?

No. It closed on October 7, 2021. A newer notice is open: HT942526BCRPCREA2, closes November 18, 2026 (11 days left).

Who can apply for DoD Traumatic Brain Injury and Psychological Health, Investigator-Initiated Research Award?

Defense Health Agency Contracting Activity - DHACA accepted applications from any type of organization.

What is the deadline for DoD Traumatic Brain Injury and Psychological Health, Investigator-Initiated Research Award?

Closed October 7, 2021. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

About $11.3 million in total across about 15 awards.

Who has won Military Medical Research and Development grants before?

The largest recipients over five fiscal years were The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., The Univeristy of Texas M.D. Anderson Cancer Center, The Johns Hopkins University. The program made 5,470 awards worth $6.9 billion in that time.

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