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Grants / Department of Defense / Defense Health Agency Contracting Activity - DHACA

W81XWH-21-PRORP-CTRA: DoD Peer Reviewed Orthopaedic, Clinical Translational Research Award

Closed Closed September 10, 2021 Opportunity W81XWH-21-PRORP-CTRA

This grant is closed. A newer notice from the same program is open now: DoW Breast Cancer, Clinical Research Extension Award (HT942526BCRPCREA2). Status: Closes November 18, 2026 (11 days left). It is in our archive of Defense Health Agency Contracting Activity - DHACA notices from 2021.

Defense Health Agency Contracting Activity - DHACA offered grants to any type of organization. It expected to make about 5 awards worth $7.5 million in total. Applications closed on September 10, 2021.

From the official notice on Grants.gov, last changed April 1, 2021. Checked November 7, 2026.

Other notices with this title

Defense Health Agency Contracting Activity - DHACA has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
HT942524PRORPCTRAMay 9, 2024Closed September 17, 2024Closed
HT9425-23-PRORP-CTRAApril 19, 2023Closed September 13, 2023Closed
W81XWH-22-PRORP-CTRAApril 8, 2022Closed September 13, 2022Closed

Key dates

PostedApril 1, 2021
DeadlineSeptember 10, 2021
Archived by Grants.govOctober 10, 2021

Who can apply

This opportunity was open to any type of organization.

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Is this a realistic fit?

What the grant funds

The PRORP CTRA is intended to support high-impact and/or new/emerging clinical research that may or may not be ready for a full-scale randomized controlled clinical trial. Projects should demonstrate potential to impact the standard of care, both immediate and long-term, as well as contribute to evidence-based guidelines for the evaluation and care of military, Veteran, and all patients with orthopaedic injuries. • One goal of the FY21 PRORP CTRA is to translate current and emerging techniques and interventions into the clinical space to better serve military patients. The health, functional abilities, and quality of life of individuals who have sustained an orthopaedic injury should be considered. • Another goal is to identify the most effective diagnosis, treatment, rehabilitation, and prevention options available to support critical decision-making for patients, clinicians, other caregivers, and policymakers. The FY21 PRORP CTRA differs from the FY21 PRORP Clinical Trial Award (CTA) in that the CTRA allows for clinical research projects, whereas the CTA is restricted to clinical trials only. Applications to the FY21 PRORP Clinical Translational Research Award mechanism must support clinical research and may not be used for animal research. The proposed studies may be interventional and may involve some retrospective data analysis. Note that purely retrospective or database-related research is not allowed under this funding opportunity. Small pilot clinical trials with human subjects are allowable. Clinical research is defined as: (1) patient-oriented research. Research conducted with human subjects (or on material of human origin such as tissues, specimens, and cognitive phenomena) for which an investigator (or colleague) directly interacts with human subjects. Excluded from this definition are in vitro studies that utilize human tissues that cannot be linked to a living individual. Patient-oriented research includes: (a) mechanisms of human disease, (b) therapeutic interventions, (c) clinical trials, and (d) development of new technologies; (2) epidemiologic and behavioral studies; and (3) outcomes research and health services research. Note: Studies that meet the requirements for Institutional Review Board (IRB) review Exemption 4 are not considered CDMRP-defined clinical research. IRB Exemption 4 refers to research involving the collection or study of existing de-identified specimens or data, if these sources are publicly available.

Category: Science and Technology and other Research and Development.

Who has won Military Medical Research and Development grants before

From fiscal 2021 to 2025, Military Medical Research and Development (12.420) awarded $6.9 billion across 5,470 grant awards, an average of $1.3 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.Maryland81$546 million
The Univeristy of Texas M.D. Anderson Cancer CenterTexas139$166 million
The Johns Hopkins UniversityMaryland157$153 million
The Regents of the University of California, San FranciscoCalifornia113$147 million
Duke UniversityNorth Carolina86$123 million

Top states: Maryland ($793 million), California ($751 million), Texas ($598 million), Massachusetts ($586 million), New York ($508 million).

Applying now

This notice no longer takes applications. Apply under the newer notice, HT942526BCRPCREA2, which is open now.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is W81XWH-21-PRORP-CTRA still open?

No. It closed on September 10, 2021. A newer notice is open: HT942526BCRPCREA2, closes November 18, 2026 (11 days left).

Who can apply for DoD Peer Reviewed Orthopaedic, Clinical Translational Research Award?

Defense Health Agency Contracting Activity - DHACA accepted applications from any type of organization.

What is the deadline for DoD Peer Reviewed Orthopaedic, Clinical Translational Research Award?

Closed September 10, 2021. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

About $7.5 million in total across about 5 awards.

Who has won Military Medical Research and Development grants before?

The largest recipients over five fiscal years were The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., The Univeristy of Texas M.D. Anderson Cancer Center, The Johns Hopkins University. The program made 5,470 awards worth $6.9 billion in that time.

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