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Grants / Department of Defense / Defense Health Agency Contracting Activity - DHACA

W81XWH-21-PRMRP-TTDA: CDMRP PRMRP Technology/Therapeutic Development Award

Closed Closed September 2, 2021 Opportunity W81XWH-21-PRMRP-TTDA

This grant is closed. A newer notice from the same program is open now: DoW Breast Cancer, Clinical Research Extension Award (HT942526BCRPCREA2). Status: Closes November 18, 2026 (11 days left). It is in our archive of Defense Health Agency Contracting Activity - DHACA notices from 2021.

Defense Health Agency Contracting Activity - DHACA offered grants to any type of organization. It expected to make about 19 awards worth $72.0 million in total. Applications closed on September 2, 2021.

From the official notice on Grants.gov, last changed March 15, 2021. Checked November 7, 2026.

Key dates

PostedMarch 15, 2021
DeadlineSeptember 2, 2021
Archived by Grants.govOctober 2, 2021

Who can apply

This opportunity was open to any type of organization.

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Is this a realistic fit?

What the grant funds

The PRMRP Technology/Therapeutic Development Award is a product-driven award mechanism intended to provide support for the translation of promising preclinical findings into products for clinical applications, including prevention, detection, diagnosis, treatment, or quality of life, in at least one of the Congressionally directed FY21 PRMRP Topic Areas. Products in development should be responsive to the healthcare needs of military Service Members, Veterans, and/or beneficiaries. The product(s) to be developed may be a tangible item such as a pharmacologic agent (drugs or biologics) or device, or a knowledge-based product. (A “knowledge product” is a non-materiel product that addresses an identified need in a Topic Area, is based on current evidence and research, aims to transition into medical practice, training, tools, or to support materiel solutions [systems to develop, acquire, provide, and sustain medical solutions and capabilities], and educates or impacts behavior throughout the continuum of care, including primary prevention of negative outcomes.) The Principal Investigator (PI) must provide a transition plan (including potential funding and resources, see Attachment 8) showing how the product will progress to the next level of development (e.g., clinical trials, delivery to the military or civilian market) after the completion of the PRMRP award. PIs are encouraged to develop relationships with industry and/or other funding agencies to facilitate moving the product into the next phase of development. Proof of concept demonstrating the potential utility of the proposed product, or a prototype/ preliminary version of the proposed product, should already be established. Applications must include relevant data that support the rationale for the proposed study. These data may be unpublished and/or from the published literature. Investigators seeking to identify a product or demonstrate initial proof of concept should consider submitting to the FY21 PRMRP Investigator-Initiated Research Award (Funding Opportunity Number W81XWH-21-PRMRP-IIRA) or the FY21 PRMRP Discovery Award (Funding Opportunity Number W81XWH-21-PRMRP-DA), as appropriate. Research proposed under this award mechanism may be at different stages of idea and research development. Two different funding levels, based on the scope of the research, are available under this program announcement. The applicant must select the funding level that is most appropriate for the research proposed.

Category: Science and Technology and other Research and Development.

Who has won Military Medical Research and Development grants before

From fiscal 2021 to 2025, Military Medical Research and Development (12.420) awarded $6.9 billion across 5,470 grant awards, an average of $1.3 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.Maryland81$546 million
The Univeristy of Texas M.D. Anderson Cancer CenterTexas139$166 million
The Johns Hopkins UniversityMaryland157$153 million
The Regents of the University of California, San FranciscoCalifornia113$147 million
Duke UniversityNorth Carolina86$123 million

Top states: Maryland ($793 million), California ($751 million), Texas ($598 million), Massachusetts ($586 million), New York ($508 million).

Applying now

This notice no longer takes applications. Apply under the newer notice, HT942526BCRPCREA2, which is open now.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is W81XWH-21-PRMRP-TTDA still open?

No. It closed on September 2, 2021. A newer notice is open: HT942526BCRPCREA2, closes November 18, 2026 (11 days left).

Who can apply for CDMRP PRMRP Technology/Therapeutic Development Award?

Defense Health Agency Contracting Activity - DHACA accepted applications from any type of organization.

What is the deadline for CDMRP PRMRP Technology/Therapeutic Development Award?

Closed September 2, 2021. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

About $72.0 million in total across about 19 awards.

Who has won Military Medical Research and Development grants before?

The largest recipients over five fiscal years were The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., The Univeristy of Texas M.D. Anderson Cancer Center, The Johns Hopkins University. The program made 5,470 awards worth $6.9 billion in that time.

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