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Grants / Department of Defense / Defense Health Agency Contracting Activity - DHACA

W81XWH-21-OPORP-CRA: DOD Orthotics and Prosthetics Outcomes, Clinical Research Award

Closed Closed July 29, 2021 Opportunity W81XWH-21-OPORP-CRA

This grant is closed. A newer notice from the same program is open now: DoW Breast Cancer, Clinical Research Extension Award (HT942526BCRPCREA2). Status: Closes November 18, 2026 (11 days left). It is in our archive of Defense Health Agency Contracting Activity - DHACA notices from 2021.

Defense Health Agency Contracting Activity - DHACA offered grants to any type of organization. It expected to make about 4 awards worth $15.0 million in total. Applications closed on July 29, 2021.

From the official notice on Grants.gov, last changed April 1, 2021. Checked November 7, 2026.

Other notices with this title

Defense Health Agency Contracting Activity - DHACA has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
HT9425-23-OPORP-CRAApril 27, 2023Closed July 12, 2023Closed
W81XWH-22-OPORP-CRAMarch 22, 2022Closed June 1, 2022Closed

Key dates

PostedApril 1, 2021
DeadlineJuly 29, 2021
Archived by Grants.govAugust 28, 2021

Who can apply

This opportunity was open to any type of organization.

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Is this a realistic fit?

What the grant funds

The FY21 OPORP CRA is intended to support clinical research that evaluates orthoses and/or prostheses using patient-centric outcomes relevant to Service Members, Veterans, and other individuals with limb loss and/or limb impairment. Research supported by this mechanism is intended to generate clinically useful evidence with potential to optimize patient outcomes and inform clinical or policy decisions. The FY21 OPORP is also interested in multidisciplinary projects that address strategies to mitigate secondary injuries. Studies proposing or evaluating rehabilitation strategies must indicate how the rehabilitation may improve the orthotic or prosthetic device outcome when compared to standard of care. The FY21 OPORP CRA offers funding for two Funding Levels (Refer to Section II.D.5, Funding Restrictions). Only one Funding Level category may be chosen per application, and the choice of application category is at the discretion of the applicant. The following are generalized descriptions of the scope of research appropriate for each Funding Level: • Funding Level 1 supports pilot and early-stage research studies that are exploratory and involve limited human exposure (e.g., small sample size), with the potential to make significant advancements toward clinical translation. Preliminary data are encouraged but not required for this Funding Level. • Funding Level 2 supports large clinical research projects that involve robust, statistically relevant participant numbers, with the potential to make significant advancement toward clinical translation. Proposed projects may include large-scale studies that, if successful, will generate high-quality outcomes that provide strong, definitive support for evidence-based practice and/or have the potential to drive changes in clinical practice. Pragmatic studies and comparative effectiveness studies are welcome and encouraged. Preliminary data relevant to the proposed clinical study are required for this Funding Level.

Category: Science and Technology and other Research and Development.

Who has won Military Medical Research and Development grants before

From fiscal 2021 to 2025, Military Medical Research and Development (12.420) awarded $6.9 billion across 5,470 grant awards, an average of $1.3 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.Maryland81$546 million
The Univeristy of Texas M.D. Anderson Cancer CenterTexas139$166 million
The Johns Hopkins UniversityMaryland157$153 million
The Regents of the University of California, San FranciscoCalifornia113$147 million
Duke UniversityNorth Carolina86$123 million

Top states: Maryland ($793 million), California ($751 million), Texas ($598 million), Massachusetts ($586 million), New York ($508 million).

Applying now

This notice no longer takes applications. Apply under the newer notice, HT942526BCRPCREA2, which is open now.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is W81XWH-21-OPORP-CRA still open?

No. It closed on July 29, 2021. A newer notice is open: HT942526BCRPCREA2, closes November 18, 2026 (11 days left).

Who can apply for DOD Orthotics and Prosthetics Outcomes, Clinical Research Award?

Defense Health Agency Contracting Activity - DHACA accepted applications from any type of organization.

What is the deadline for DOD Orthotics and Prosthetics Outcomes, Clinical Research Award?

Closed July 29, 2021. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

About $15.0 million in total across about 4 awards.

Who has won Military Medical Research and Development grants before?

The largest recipients over five fiscal years were The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., The Univeristy of Texas M.D. Anderson Cancer Center, The Johns Hopkins University. The program made 5,470 awards worth $6.9 billion in that time.

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