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W81XWH-21-CPMRP-CEA: DOD Chronic Pain Management, Clinical Exploration Award

Closed Closed November 12, 2021 Opportunity W81XWH-21-CPMRP-CEA

This grant is closed. A newer notice from the same program is open now: DoW Breast Cancer, Clinical Research Extension Award (HT942526BCRPCREA2). Status: Closes November 18, 2026 (11 days left). It is in our archive of Defense Health Agency Contracting Activity - DHACA notices from 2021.

Defense Health Agency Contracting Activity - DHACA offered grants to any type of organization. It expected to make about 4 awards worth $1.6 million in total. Applications closed on November 12, 2021.

From the official notice on Grants.gov, last changed June 15, 2021. Checked November 7, 2026.

Other notices with this title

Defense Health Agency Contracting Activity - DHACA has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
HT9425-23-CPMRP-CEAJuly 3, 2023Closed November 9, 2023Closed
W81XWH-22-CPMRP-CEAMay 24, 2022Closed October 13, 2022Closed

Key dates

PostedJune 15, 2021
DeadlineNovember 12, 2021
Archived by Grants.govDecember 12, 2021

Who can apply

This opportunity was open to any type of organization.

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Is this a realistic fit?

What the grant funds

The intent of the FY21 CPMRP CEA is to support proof-of-principle pilot studies, clinical trials, and correlative studies to investigate hypothesis-based, innovative interventions and/or avenues of research that have the potential to resolve current clinical barriers and result in a profound impact on the management of chronic pain. While therapeutic approaches proposed for testing through the CEA must represent novel, hypothesis-based, “outside-the-box” approaches for managing chronic pain, they may include therapies already in clinical use, or undergoing clinical testing, for other diseases, provided that the proposed use for chronic pain management would lead to a major advancement in patient care. CEA applications should explain how the proposed work will address a gap in clinical knowledge and enable future studies to transform clinical care for chronic pain management. It is anticipated that outcomes from studies funded by this award will provide scientific rationale for subsequent larger clinical trials of interventions that will transform chronic pain management and/or clinical care. Studies seeking to advance new and novel opioid-based therapeutic interventions do not meet the intent of the award mechanism and may be withdrawn. Studies seeking to understand and reduce opioid utilization in chronic pain management within the context of current prescribing practices are acceptable.

Category: Science and Technology and other Research and Development.

Who has won Military Medical Research and Development grants before

From fiscal 2021 to 2025, Military Medical Research and Development (12.420) awarded $6.9 billion across 5,470 grant awards, an average of $1.3 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.Maryland81$546 million
The Univeristy of Texas M.D. Anderson Cancer CenterTexas139$166 million
The Johns Hopkins UniversityMaryland157$153 million
The Regents of the University of California, San FranciscoCalifornia113$147 million
Duke UniversityNorth Carolina86$123 million

Top states: Maryland ($793 million), California ($751 million), Texas ($598 million), Massachusetts ($586 million), New York ($508 million).

Applying now

This notice no longer takes applications. Apply under the newer notice, HT942526BCRPCREA2, which is open now.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is W81XWH-21-CPMRP-CEA still open?

No. It closed on November 12, 2021. A newer notice is open: HT942526BCRPCREA2, closes November 18, 2026 (11 days left).

Who can apply for DOD Chronic Pain Management, Clinical Exploration Award?

Defense Health Agency Contracting Activity - DHACA accepted applications from any type of organization.

What is the deadline for DOD Chronic Pain Management, Clinical Exploration Award?

Closed November 12, 2021. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

About $1.6 million in total across about 4 awards.

Who has won Military Medical Research and Development grants before?

The largest recipients over five fiscal years were The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., The Univeristy of Texas M.D. Anderson Cancer Center, The Johns Hopkins University. The program made 5,470 awards worth $6.9 billion in that time.

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