Grants / Department of Agriculture / Animal and Plant Health Inspection Service

USDA-APHIS-10025-OA000000-26-0001: New World Screwworm Grand Challenge

Closed Closed February 23, 2026 Opportunity USDA-APHIS-10025-OA000000-26-0001 ☆ Save

This grant is closed. A newer notice from the same program is open now: National Animal Disease Preparedness and Response Program (NADPRP) FY 2027 State Preparedness Funding Opportunity (USDA-APHIS-10025-VSSP0000-27-0002). Status: Closes January 7, 2027 (61 days left). It is in our archive of Animal and Plant Health Inspection Service notices from 2026.

• Award ceiling$5.0 million
• Total funding$100 million
• Expected awards20
• Cost sharingNot required
• Funding typeCooperative Agreement

Key dates

Who can apply

This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes and small businesses.

Application packages must meet the initial screening criteria to be eligible to receive further review. Proposals that do not meet these initial screening criteria will not receive further review. Any application package with missing or incomplete documents or forms will not be eligible to receive further review.1. Proposals must be submitted by eligible entities with an active Unique Entity Identifier (UEI) in SAM.gov. 2. Proposals must address one of the funding priorities listed in Section 1 and described in detail in Appendix 1 of the Notice of Funding Opportunity.3. All required documents and forms listed in Section 4 of the Notice of Funding Opportunity must (a) be included in the application package, and (b) comply with the submission instructions described in Section 5 of the Notice of Funding Opportunity.4. Proposals, including all associated documents and forms, must be received on or before the proposal submission deadline. Proposals received after the submission deadline will not be eligible to receive further review.

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses.

Is this a realistic fit?

• Past Animal Disease and Animal Care awards averaged $283,499; this notice allows up to $5.0 million per award.
• Most of the program's money (52% over five years) went to state and local governments.
• No cost sharing or match is required.

What the grant funds

The United States Department of Agriculture, Animal Health Protection Inspection Service announces this funding opportunity to support the sweeping plan to combat New World screwworm (NWS) as described in the U.S. Secretary of Agriculture’s August 15, 2025, press release, titled USDA Announces Sweeping Plans to Protect the United States from New World Screwworm. Through this Grand Challenge, APHIS is making up to $100,000,000 available to combat NWS and prevent its northward spread. APHIS is making rapid progress on the construction of additional sterile insect production facilities with full capacity of 300 million sterile flies per week expected to come online in March 2029. Through the Grand Challenge, APHIS hopes to identify both projects that will augment our rapid response to the growing threat of NWS to serve as an interim step while production increases, but also long-term investments that expand our ability to respond to the parasite now and into the future – technologies that, perhaps, could have applicability with other animal disease response programs. APHIS will support projects that enhance sterile NWS fly production, develop novel NWS traps and lures, develop and increase understanding of NWS therapeutics/treatments in animals, or develop other tools to bolster preparedness or response to NWS. Funding Priorities: APHIS will support projects that: Topic 1: Enhance sterile NWS fly production. Topic 2: Develop novel NWS traps and lures. Topic 3: Develop and increase understanding of NWS therapeutic/treatments (i.e. products that could treat, prevent, or control NWS) for animals and that could be stockpiled and used in animals should NWS reach the United States. Topic 4: Develop other tools to bolster preparedness or response to NWS. Awards are not anticipated to exceed $5,000,000; however, APHIS reserves the right to award proposals in excess of $5,000,000 if the proposal significantly contributes to the prevention of NWS’ northward spread. This anticipated award amount should not deter new innovations; Major projects with a demonstrable ability to rapidly advance animal health outcomes and/or delay the spread of NWS will be considered in excess of this amount. You can See Appendix I for funding priority topics. APHIS may award less than the requested amount for a project. In these cases, applicants may accept or decline the award that is offered.

Category: Agriculture.

Applying now

This notice no longer takes applications. Apply under the newer notice, USDA-APHIS-10025-VSSP0000-27-0002, which is open now.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.