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Grants / Department of Health and Human Services / Centers for Disease Control and Prevention - ERA

RFA-OH-25-001: Exploratory/Developmental Research for World Trade Center Health Program Evidence-based Strategies to Improve Treatment Effectiveness, Diagnostic Practices, and Program Evaluation (R21)

Closed Closed October 29, 2024 Opportunity RFA-OH-25-001

This grant is closed. A newer notice from the same program is open now: Exploratory/Developmental Grants Related to the World Trade Center Health Program (R21) (RFA-OH-26-015). Status: Closes December 8, 2026 (31 days left). It is in our archive of Centers for Disease Control and Prevention - ERA notices from 2024.

Centers for Disease Control and Prevention - ERA offered grants to any type of organization. It expected to make about 8 awards worth $4.0 million in total. Applications closed on October 29, 2024.

From the official notice on Grants.gov, last changed May 9, 2024. Checked November 7, 2026.

Key dates

PostedMay 9, 2024
DeadlineOctober 29, 2024
Archived by Grants.govNovember 28, 2024

Who can apply

This opportunity was open to any type of organization.

All 15 applicant types the notice lists

N/A

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses, individuals.

Is this a realistic fit?

What the grant funds

The National Institute for Occupational Safety and Health (NIOSH) supports exploratory and developmental research projects (R21) that address issues related to diagnostic or treatment uncertainty with respect to individuals receiving monitoring and/or treatment under subtitle C of the James Zadroga 9/11 Health and Compensation Act of 2010.The Zadroga Act lists the following broad research areas:Physical and mental health conditions that may be related to the September 11, 2001, terrorist attacks;Diagnosing WTC-related health conditions for which there has been diagnostic uncertainty; andTreating WTC-related health conditions for which there has been treatment uncertainty. The WTC Health Program intends to increase opportunities for research on new, innovative approaches, interventions, techniques, or methodologies to improve treatment and diagnostic effectiveness through intervention, as well as support program evaluation. The WTC Health Program seeks to achieve a suitable mix of meritorious research projects which assess the feasibility of enhancing interventions and program evaluations to improve diagnosis, treatment, care, and well-being of 9/11-exposed populations. Research areas of interest include clinical, screening, diagnostic, epidemiological, treatment, prevention, translation, and program evaluation. WTC responders, screening-eligible WTC survivors, and certified-eligible WTC survivors comprise the population targeted for the research project. The research should consider health equity initiatives in design, where possible. Opportunities for future health effects research involving vulnerable groups of persons (e.g., minorities, women, children, and other potentially disadvantaged groups) who were exposed to the 9/11 attacks and aftermath are of special interest. Research is needed to identify at-risk groups, characterize the health burden, and inform care. This WTC Health Program R21 Notice of Funding Opportunity (NOFO) is intended to encourage exploratory/developmental research by providing support for the early and conceptual stages of project development which assess the feasibility of new areas of investigation with the potential to enhance treatment effectiveness and diagnostic practices. These studies may lead to breakthroughs in a particular area, or to the development of new interventions, techniques, agents, methodologies, models, or approaches with major clinical impacts.

Category: Health.

Who has won Occupational Safety and Health Program grants before

From fiscal 2021 to 2025, Occupational Safety and Health Program (93.262) awarded $590 million across 305 grant awards, an average of $1.9 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
City of New YorkNew York1$39.5 million
CPWR: the Center for Construction Research and TrainingMaryland2$27.2 million
The University of IowaIowa5$23.6 million
University of IllinoisIllinois5$21.2 million
Icahn School of Medicine at Mount SinaiNew York16$18.9 million

Top states: New York ($96.2 million), Maryland ($45.5 million), California ($44.4 million), Colorado ($27.7 million), Massachusetts ($26.9 million).

Applying now

This notice no longer takes applications. Apply under the newer notice, RFA-OH-26-015, which is open now.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is RFA-OH-25-001 still open?

No. It closed on October 29, 2024. A newer notice is open: RFA-OH-26-015, closes December 8, 2026 (31 days left).

Who can apply for Exploratory/Developmental Research for World Trade Center Health Program Evidence-based Strategies to Improve Treatment Effectiveness, Diagnostic Practices, and Program Evaluation (R21)?

Centers for Disease Control and Prevention - ERA accepted applications from any type of organization. The notice adds further conditions, so read its eligibility section.

What is the deadline for Exploratory/Developmental Research for World Trade Center Health Program Evidence-based Strategies to Improve Treatment Effectiveness, Diagnostic Practices, and Program Evaluation (R21)?

Closed October 29, 2024. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

About $4.0 million in total across about 8 awards.

Who has won Occupational Safety and Health Program grants before?

The largest recipients over five fiscal years were City of New York, CPWR: the Center for Construction Research and Training, The University of Iowa. The program made 305 awards worth $590 million in that time.

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