Well Told Grants

Grants / Department of Health and Human Services / National Institutes of Health

RFA-NS-22-067: Stroke Preclinical Assessment Network (SPAN) to Support Translational Studies for Acute Cerebroprotection- Interventions from Small Businesses (U44 Clinical Trial Not Allowed)

Closed Closed July 28, 2022 Opportunity RFA-NS-22-067

This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2022.

National Institutes of Health offered grants of up to $300,000 to small businesses. Applications closed on July 28, 2022.

From the official notice on Grants.gov, last changed May 25, 2022. Checked November 7, 2026.

About this NIH notice

Projects funded under RFA-NS-22-067 were run by National Institute of Neurological Disorders and Stroke (NINDS, 1 project). Contact the program officer at the institute that fits your project before you apply; the notice lists them.

Application due dates, page limits and budget limits are set in the notice. Read RFA-NS-22-067 in the NIH Guide.

Other notices with this title

National Institutes of Health has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
RFA-NS-22-033January 6, 2022Closed March 14, 2022Closed

Key dates

PostedMay 24, 2022
DeadlineJuly 28, 2022
Archived by Grants.govSeptember 2, 2022

Who can apply

This opportunity was open to small businesses.

Other Eligible Applicants include the following: Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, may be allowed. See Full Announcement for full Eligibility details

More grants for small businesses.

Is this a realistic fit?

What the grant funds

The purpose of this funding opportunity announcement (FOA) is to invite applications for Phase II SBIR applications to test promising cerebrovascular interventions in the NINDS Stroke Preclinical Assessment Network (SPAN). SPAN will facilitate the testing of up to 8 promising cerebroprotective drugs or interventions to be given prior to or at the time of reperfusion in experimental models of ischemic stroke (e.g., transient middle cerebral artery occlusion (tMCAo)). The PIs of the awarded interventions will become part of the network and will collaborate with the SPAN Coordinating Center (RFA-NS-22-004), testing laboratories (RFA-NS-22-003), and other intervention contributors (RFA-NS-22-066, RFA-NS-22-067) to facilitate the parallel testing of multiple cerebroprotective interventions in experimental models of ischemic stroke. Applicants must propose a research project involving a promising cerebroprotective intervention, supported by rigorous and extensive preliminary data, to be tested in SPAN. If successful, this network will accelerate the identification of the most promising cerebroprotective therapies for future pivotal clinical trials and span the gap between small businesses, preclinical testing laboratories, and a pipeline to clinical testing, in a cost-and time-effective fashion.

Category: Health.

Funded under RFA-NS-22-067 so far

NIH funded 1 project under RFA-NS-22-067 in fiscal 2023 to 2025, at 1 institution. The median yearly award was $299,550.

Recently funded projects
ProjectInstitutionFiscal yearAward
Comparative testing of tatCN19o for neuroprotection in rodent tMCAo U44Neurexis Therapeutics, Inc.2025$299,550

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Extramural Research Programs in the Neurosciences and Neurological Disorders grants before

From fiscal 2021 to 2025, Extramural Research Programs in the Neurosciences and Neurological Disorders (93.853) awarded $9.1 billion across 8,641 grant awards, an average of $1.0 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The General Hospital CorporationMassachusetts203$288 million
The Regents of the University of California, San FranciscoCalifornia248$277 million
The Johns Hopkins UniversityMaryland230$276 million
The Trustees of Columbia University in the City of New YorkNew York188$226 million
Regents of the University of MichiganMichigan179$221 million

Top states: California ($1.4 billion), New York ($926 million), Massachusetts ($906 million), Pennsylvania ($626 million), Texas ($499 million).

Applying now

This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is RFA-NS-22-067 still open?

No. It closed on July 28, 2022.

Who can apply for Stroke Preclinical Assessment Network (SPAN) to Support Translational Studies for Acute Cerebroprotection- Interventions from Small Businesses (U44 Clinical Trial Not Allowed)?

National Institutes of Health accepted applications from small businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for Stroke Preclinical Assessment Network (SPAN) to Support Translational Studies for Acute Cerebroprotection- Interventions from Small Businesses (U44 Clinical Trial Not Allowed)?

Closed July 28, 2022. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

Awards of up to $300,000 each.

Who has been funded under RFA-NS-22-067?

NIH RePORTER lists 1 project funded under RFA-NS-22-067 in fiscal 2023 to 2025, at 1 institution.

Who has won Extramural Research Programs in the Neurosciences and Neurological Disorders grants before?

The largest recipients over five fiscal years were The General Hospital Corporation, The Regents of the University of California, San Francisco, The Johns Hopkins University. The program made 8,641 awards worth $9.1 billion in that time.

Similar open grants