RFA-MH-26-105: Multimodal Artificial Intelligence to Accelerate HIV Clinical Care (R01 Clinical Trial Optional)
Closed
This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2025.
National Institutes of Health offered grants of up to $750,000 to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on March 27, 2025.
From the official notice on Grants.gov, last changed January 10, 2025. Checked November 7, 2026.
- Award ceiling$750,000
- Cost sharingNot required
- Funding typeGrant
About this NIH notice
- Activity codeR01
- Clinical trialsOptional
- Funded byNIMH
- Median yearly award$1.1 million
- Typical project length5 years
- R01, Research Project Grant. NIH's standard grant for a defined research project led by a named investigator, usually for up to five years. Other open R01 notices.
Projects funded under RFA-MH-26-105 were run by National Institute of Mental Health (NIMH, 5 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.
Application due dates, page limits and budget limits are set in the notice. Read RFA-MH-26-105 in the NIH Guide.
Key dates
| Posted | January 10, 2025 |
|---|---|
| Deadline | March 27, 2025 |
| Archived by Grants.gov | May 2, 2025 |
Who can apply
This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.
All 15 applicant types the notice lists
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Is this a realistic fit?
- Projects NIH funded under this notice had a median yearly award of $1.1 million; it allows up to $750,000 per award.
- Most of the money in the 2 programs behind this notice (69% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
This initiative will leverage cutting edge generative AI technology to augment existing narrow AI/ML approaches used in clinical care that will expand our capacity to address the dynamic, complex, and evolving HIV epidemic.
Funded under RFA-MH-26-105 so far
NIH funded 5 projects under RFA-MH-26-105 in fiscal 2026, at 5 institutions. The median yearly award was $1.1 million.
| Project | Institution | Fiscal year | Award |
|---|---|---|---|
| SYNcronized Agentic Prescriptive System for Improving Sequentially HIV Care Continuum (SYNAPSIS-HIV-CC) | University of Florida | 2026 | $1.1 million |
| Advancing Multimodal AI/ML to Enhance HIV Clinical Care | University of Pennsylvania | 2026 | $1.2 million |
| Harnessing Multimodal AI to Reduce Virologic Failure in People Living with HIV | San Diego State University | 2026 | $1.1 million |
| Multimodal AI for Monitoring and Predicting Neurocognitive Impairment in People with HIV | University of South Carolina at Columbia | 2026 | $1.0 million |
| AI-driven Multimodal Model for PrEP Candidacy Assessment in Women (AiM-PrEP) | Duke University | 2026 | $1.2 million |
Who has won Mental Health Research Grants grants before
From fiscal 2021 to 2025, Mental Health Research Grants (93.242) awarded $8.8 billion across 6,785 grant awards, an average of $1.3 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Yale Univ | Connecticut | 185 | $371 million |
| University of Pittsburgh - of the Commonwealth System of Higher Education | Pennsylvania | 200 | $297 million |
| University of California, Los Angeles | California | 176 | $234 million |
| Icahn School of Medicine at Mount Sinai | New York | 144 | $212 million |
| The Washington University | Missouri | 149 | $211 million |
Who has won Drug Use and Addiction Research Programs grants before
From fiscal 2021 to 2025, Drug Use and Addiction Research Programs (93.279) awarded $7.3 billion across 5,071 grant awards, an average of $1.4 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Yale Univ | Connecticut | 150 | $305 million |
| The Johns Hopkins University | Maryland | 156 | $262 million |
| University of California, San Diego | California | 120 | $242 million |
| University of Pittsburgh - of the Commonwealth System of Higher Education | Pennsylvania | 100 | $182 million |
| New York University | New York | 62 | $173 million |
Applying now
This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is RFA-MH-26-105 still open?
No. It closed on March 27, 2025.
Who can apply for Multimodal Artificial Intelligence to Accelerate HIV Clinical Care (R01 Clinical Trial Optional)?
National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.
What is the deadline for Multimodal Artificial Intelligence to Accelerate HIV Clinical Care (R01 Clinical Trial Optional)?
Closed March 27, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.
How much funding is available?
Awards of up to $750,000 each.
Who has been funded under RFA-MH-26-105?
NIH RePORTER lists 5 projects funded under RFA-MH-26-105 in fiscal 2026, at 5 institutions. The most were at University of Florida, University of Pennsylvania, San Diego State University.
Who has won Mental Health Research Grants grants before?
The largest recipients over five fiscal years were Yale Univ, University of Pittsburgh - of the Commonwealth System of Higher Education, University of California, Los Angeles. The program made 6,785 awards worth $8.8 billion in that time.
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