RFA-MH-25-135: Research Opportunities in Crisis Response Services for Suicide Prevention (R01 Clinical Trial Optional)
Closed
This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2024.
National Institutes of Health offered grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on December 9, 2025.
From the official notice on Grants.gov, last changed December 9, 2025. Checked November 7, 2026.
- Award amountsNot given on Grants.gov
- Cost sharingNot required
- Funding typeGrant
About this NIH notice
- Activity codeR01
- Clinical trialsOptional
- Funded byNIMH
- Median yearly award$955,405
- Typical project length5 years
- R01, Research Project Grant. NIH's standard grant for a defined research project led by a named investigator, usually for up to five years. Other open R01 notices.
Projects funded under RFA-MH-25-135 were run by National Institute of Mental Health (NIMH, 4 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.
Application due dates, page limits and budget limits are set in the notice. Read RFA-MH-25-135 in the NIH Guide.
Key dates
| Posted | June 13, 2024 |
|---|---|
| Deadline | December 9, 2025 |
| Archived by Grants.gov | February 7, 2026 |
Who can apply
This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.
All 15 applicant types the notice lists
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Is this a realistic fit?
- Most of the program's money (69% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
As part of the Suicide Prevention Transformative Project workgroups research agenda, the purpose of this Notice of Funding Opportunity (NOFO) is to support research examining the impact of state and local policy on the introduction, implementation and outcomes of crisis response services, including those under the 988 rollout (e.g., research focused on how policy impacts the availability, use, nature, and outcomes of services). Research is sought that is conducted in real-world settings, where a wide range of clinical presentations, psychosocial factors, age-related (e.g., youth; adult; older adult), geographic (rural/remote settings), cultural considerations, and health disparities influence the types of care that are provided. Studies are encouraged that address the continuum of crisis service systems, as well as applications that address crisis services for children and under-resourced populations.
Funded under RFA-MH-25-135 so far
NIH funded 4 projects under RFA-MH-25-135 in fiscal 2025 to 2026, at 4 institutions. The median yearly award was $955,405.
| Project | Institution | Fiscal year | Award |
|---|---|---|---|
| THRIVE: Hybrid Randomized Effectiveness-Implementation Trial of a Recovery-Focused Suicide Prevention Intervention for Crisis Stabilization Centers | University of Alabama at Birmingham | 2026 | $726,339 |
| The impact and mechanisms of mobile response services for individuals experiencing behavioral health crisis | University of California Berkeley | 2026 | $815,743 |
| INSPIRE: Innovations in Suicide Prevention Research | Univ of North Carolina Chapel Hill | 2026 | $980,614 |
| Experiences Using and Intentions to Use the 988 Suicide & Crisis Lifeline Among Distressed Adults | New York University | 2026 | $2.4 million |
Who has won Mental Health Research Grants grants before
From fiscal 2021 to 2025, Mental Health Research Grants (93.242) awarded $8.8 billion across 6,785 grant awards, an average of $1.3 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Yale Univ | Connecticut | 185 | $371 million |
| University of Pittsburgh - of the Commonwealth System of Higher Education | Pennsylvania | 200 | $297 million |
| University of California, Los Angeles | California | 176 | $234 million |
| Icahn School of Medicine at Mount Sinai | New York | 144 | $212 million |
| The Washington University | Missouri | 149 | $211 million |
Applying now
This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is RFA-MH-25-135 still open?
No. It closed on December 9, 2025.
Who can apply for Research Opportunities in Crisis Response Services for Suicide Prevention (R01 Clinical Trial Optional)?
National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.
What is the deadline for Research Opportunities in Crisis Response Services for Suicide Prevention (R01 Clinical Trial Optional)?
Closed December 9, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.
Who has been funded under RFA-MH-25-135?
NIH RePORTER lists 4 projects funded under RFA-MH-25-135 in fiscal 2025 to 2026, at 4 institutions. The most were at University of Alabama at Birmingham, University of California Berkeley, Univ of North Carolina Chapel Hill.
Who has won Mental Health Research Grants grants before?
The largest recipients over five fiscal years were Yale Univ, University of Pittsburgh - of the Commonwealth System of Higher Education, University of California, Los Angeles. The program made 6,785 awards worth $8.8 billion in that time.
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