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Grants / Department of Health and Human Services / National Institutes of Health

RFA-HL-24-005: Limited Competition: Small Grant Program for NHLBI K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional)

Closed Closed January 7, 2025 Opportunity RFA-HL-24-005

This grant is closed. A newer notice from the same program is open now: Limited Competition: Small Grant Program for NHLBI K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional) (RFA-HL-27-004). Status: Closes November 7, 2028 (731 days left). It is in our archive of National Institutes of Health notices from 2022.

National Institutes of Health offered grants of up to $75,000 to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on January 7, 2025.

From the official notice on Grants.gov, last changed December 16, 2024. Checked November 7, 2026.

About this NIH notice

Projects funded under RFA-HL-24-005 were run by National Heart Lung and Blood Institute (NHLBI, 51 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.

Application due dates, page limits and budget limits are set in the notice. Read RFA-HL-24-005 in the NIH Guide.

Other notices with this title

National Institutes of Health has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
RFA-HL-27-004May 12, 2026Closes November 7, 2028 (731 days left)Open
RFA-HL-25-011December 16, 2024Closed January 7, 2026Closed

Key dates

PostedOctober 14, 2022
DeadlineJanuary 7, 2025
Archived by Grants.govFebruary 6, 2025

Who can apply

This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

All 15 applicant types the notice lists

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses.

Is this a realistic fit?

What the grant funds

The purpose of this funding opportunity announcement (FOA) is to solicit current or recently completed NHLBI K01, K08, K23, and K25 awardees for small grant support to expand their current research objectives or to branch out to a new study that resulted from the research conducted under the K award. Active NHLBI K01, K08, K23, and K25 awardees may apply for R03 support after the notices of award (NoA) for their first type-5 K awards have been issued. Recently completed NHLBI K01, K08, K23, and K25 awardees are eligible to apply for the R03 if the earliest possible R03 start date falls within 2 years of their prior NHLBI K award Project Period end date. This FOA is intended to enhance the capability of NHLBI K01, K08, K23, and K25 awardees to conduct research as they complete their transition to fully independent investigator status. This R03 grant mechanism is intended to support research projects that can be carried out and completed within a short period of time (no more than two years) with limited resources and that may generate preliminary data to support a subsequent R01-equivalent application. These studies include, but not limited to, pilot or feasibility studies; proof of concept studies; secondary analysis of existing data; small, self-contained research projects; development of new research methodologies or technologies, or development of novel experimental models. For current and previous K23 awardees, research proposed in the R03 application may or may not include patient-oriented research. A minimum of 40% protected overall research effort is required from applicants during the R03 award period and can be met through a combination of effort on the proposed R03 and other research projects, regardless of funding source.

Category: Health.

Funded under RFA-HL-24-005 so far

NIH funded 51 projects under RFA-HL-24-005 in fiscal 2024 to 2026, at 31 institutions. The median yearly award was $122,813.

Most projects: University of Colorado Denver (Colorado), 5, Massachusetts General Hospital (Massachusetts), 4, Stanford University (California), 4, Johns Hopkins University (Maryland), 2, Emory University (Georgia), 2.

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Cardiovascular Diseases Research grants before

From fiscal 2021 to 2025, Cardiovascular Diseases Research (93.837) awarded $15 billion across 11,798 grant awards, an average of $1.2 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Trustees of the University of PennsylvaniaPennsylvania313$380 million
Brigham & Womens Hospital IncMassachusetts274$374 million
Regents of the University of MichiganMichigan277$355 million
The Trustees of Columbia University in the City of New YorkNew York207$335 million
University of Pittsburgh - of the Commonwealth System of Higher EducationPennsylvania295$320 million

Top states: California ($1.8 billion), Massachusetts ($1.5 billion), New York ($1.4 billion), Pennsylvania ($1.1 billion), Ohio ($749 million).

Who has won Lung Diseases Research grants before

From fiscal 2021 to 2025, Lung Diseases Research (93.838) awarded $8.7 million across 5 grant awards, an average of $1.7 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The General Hospital CorporationMassachusetts1$5.4 million
New England Research Institutes IncMassachusetts1$2.7 million
The Trustees of the University of PennsylvaniaPennsylvania1$355,699
University of WashingtonWashington1$350,272
The Trustees of Columbia University in the City of New YorkNew York1$319,659

Top states: Massachusetts ($7.8 million), Washington ($350,272), New York ($319,659), Pennsylvania ($300,836).

Who has won Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders grants before

From fiscal 2021 to 2025, Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders (93.840) awarded $3.3 million across 9 grant awards, an average of $364,164 per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Regents of the University of ColoradoColorado1$1.5 million
Indiana Department of HealthIndiana1$558,986
Minnesota Department of HealthMinnesota1$442,754
Michigan Public Health InstituteMichigan1$311,837
City of PhiladelphiaPennsylvania1$251,231

Top states: Colorado ($1.5 million), Indiana ($558,986), Minnesota ($442,754), Michigan ($311,837), South Carolina ($191,177).

Applying now

This notice no longer takes applications. Apply under the newer notice, RFA-HL-27-004, which is open now.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is RFA-HL-24-005 still open?

No. It closed on January 7, 2025. A newer notice is open: RFA-HL-27-004, closes November 7, 2028 (731 days left).

Who can apply for Limited Competition: Small Grant Program for NHLBI K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional)?

National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for Limited Competition: Small Grant Program for NHLBI K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional)?

Closed January 7, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

Awards of up to $75,000 each.

Who has been funded under RFA-HL-24-005?

NIH RePORTER lists 51 projects funded under RFA-HL-24-005 in fiscal 2024 to 2026, at 31 institutions. The most were at University of Colorado Denver, Massachusetts General Hospital, Stanford University.

Who has won Cardiovascular Diseases Research grants before?

The largest recipients over five fiscal years were The Trustees of the University of Pennsylvania, Brigham & Womens Hospital Inc, Regents of the University of Michigan. The program made 11,798 awards worth $15 billion in that time.

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