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Grants / Department of Health and Human Services / National Institutes of Health

RFA-HL-23-010: Catalyze: Enabling Technologies and Transformative Platforms for HLBS Research (R33 - Clinical Trials Not Allowed)

Closed Closed November 22, 2024 Opportunity RFA-HL-23-010

This grant is closed. A newer notice from the same program is open now: Catalyze: Enabling Technologies and Transformative Platforms for HLBS Research (R33 - Clinical Trials Not Allowed) (RFA-HL-26-016). Status: Closes December 23, 2027 (411 days left). It is in our archive of National Institutes of Health notices from 2022.

National Institutes of Health offered grants of up to $300,000 to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on November 22, 2024.

From the official notice on Grants.gov, last changed November 22, 2024. Checked November 7, 2026.

About this NIH notice

Projects funded under RFA-HL-23-010 were run by National Heart Lung and Blood Institute (NHLBI, 10 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.

Application due dates, page limits and budget limits are set in the notice. Read RFA-HL-23-010 in the NIH Guide.

Other notices with this title

National Institutes of Health has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
RFA-HL-26-016November 22, 2024Closes December 23, 2027 (411 days left)Open

Key dates

PostedJanuary 24, 2022
DeadlineNovember 22, 2024
Archived by Grants.govDecember 22, 2024

Who can apply

This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

All 15 applicant types the notice lists

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses.

Is this a realistic fit?

What the grant funds

This Funding Opportunity Announcement (FOA) solicits grant applications to further develop enabling technologies and transformative platforms to catalyze next-generation predictive, diagnostic and therapeutic products to address heart, lung, blood, and sleep (HLBS)-related disorders and diseases. This FOA solicits R33 applications where major feasibility gaps for the enabling technology or transformative platform have already been overcome, as demonstrated with supportive preliminary data, but still requires further development and rigorous validation to encourage downstream demonstration, utilization and adoption. Well-suited applications must offer the potential to accelerate and/or transform the areas of early detection and screening, model development, clinical diagnosis, treatment, control, prevention or epidemiology, while addressing issues associated with HLBS-related diseases and disorders. Projects proposing application of existing technologies where the novelty resides in the biological or clinical target/question being pursued are not appropriate for this solicitation and will not be reviewed. This FOA is part of a suite of NHLBI Catalyze program to advance projects to the point where they can meet the entry criteria for the NHLBI Catalyze Product Definition or Preclinical FOAs.

Category: Health.

Funded under RFA-HL-23-010 so far

NIH funded 10 projects under RFA-HL-23-010 in fiscal 2023 to 2026, at 10 institutions. The median yearly award was $470,537.

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Cardiovascular Diseases Research grants before

From fiscal 2021 to 2025, Cardiovascular Diseases Research (93.837) awarded $15 billion across 11,798 grant awards, an average of $1.2 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Trustees of the University of PennsylvaniaPennsylvania313$380 million
Brigham & Womens Hospital IncMassachusetts274$374 million
Regents of the University of MichiganMichigan277$355 million
The Trustees of Columbia University in the City of New YorkNew York207$335 million
University of Pittsburgh - of the Commonwealth System of Higher EducationPennsylvania295$320 million

Top states: California ($1.8 billion), Massachusetts ($1.5 billion), New York ($1.4 billion), Pennsylvania ($1.1 billion), Ohio ($749 million).

Who has won Lung Diseases Research grants before

From fiscal 2021 to 2025, Lung Diseases Research (93.838) awarded $8.7 million across 5 grant awards, an average of $1.7 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The General Hospital CorporationMassachusetts1$5.4 million
New England Research Institutes IncMassachusetts1$2.7 million
The Trustees of the University of PennsylvaniaPennsylvania1$355,699
University of WashingtonWashington1$350,272
The Trustees of Columbia University in the City of New YorkNew York1$319,659

Top states: Massachusetts ($7.8 million), Washington ($350,272), New York ($319,659), Pennsylvania ($300,836).

Who has won Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders grants before

From fiscal 2021 to 2025, Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders (93.840) awarded $3.3 million across 9 grant awards, an average of $364,164 per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Regents of the University of ColoradoColorado1$1.5 million
Indiana Department of HealthIndiana1$558,986
Minnesota Department of HealthMinnesota1$442,754
Michigan Public Health InstituteMichigan1$311,837
City of PhiladelphiaPennsylvania1$251,231

Top states: Colorado ($1.5 million), Indiana ($558,986), Minnesota ($442,754), Michigan ($311,837), South Carolina ($191,177).

Applying now

This notice no longer takes applications. Apply under the newer notice, RFA-HL-26-016, which is open now.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is RFA-HL-23-010 still open?

No. It closed on November 22, 2024. A newer notice is open: RFA-HL-26-016, closes December 23, 2027 (411 days left).

Who can apply for Catalyze: Enabling Technologies and Transformative Platforms for HLBS Research (R33 - Clinical Trials Not Allowed)?

National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for Catalyze: Enabling Technologies and Transformative Platforms for HLBS Research (R33 - Clinical Trials Not Allowed)?

Closed November 22, 2024. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

Awards of up to $300,000 each.

Who has been funded under RFA-HL-23-010?

NIH RePORTER lists 10 projects funded under RFA-HL-23-010 in fiscal 2023 to 2026, at 10 institutions. The most were at University of North Carolina Charlotte, Massachusetts General Hospital, Vanderbilt University.

Who has won Cardiovascular Diseases Research grants before?

The largest recipients over five fiscal years were The Trustees of the University of Pennsylvania, Brigham & Womens Hospital Inc, Regents of the University of Michigan. The program made 11,798 awards worth $15 billion in that time.

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