RFA-EB-21-001: Technology Development to Reduce Health Disparities (R01 Clinical Trial Optional)
Closed
This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2021.
National Institutes of Health offered grants of up to $500,000 to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on May 2, 2025.
From the official notice on Grants.gov, last changed March 4, 2024. Checked November 7, 2026.
- Award ceiling$500,000
- Cost sharingNot required
- Funding typeGrant
About this NIH notice
- Activity codeR01
- Clinical trialsOptional
- Funded byNIBIB, NIMHD
- Median yearly award$652,377
- Typical project length4 years
- R01, Research Project Grant. NIH's standard grant for a defined research project led by a named investigator, usually for up to five years. Other open R01 notices.
Projects funded under RFA-EB-21-001 were run by National Institute of Biomedical Imaging and Bioengineering (NIBIB, 4 projects) and National Institute on Minority Health and Health Disparities (NIMHD, 3 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.
Application due dates, page limits and budget limits are set in the notice. Read RFA-EB-21-001 in the NIH Guide.
Key dates
| Posted | December 10, 2021 |
|---|---|
| Deadline | May 2, 2025 |
| Archived by Grants.gov | June 1, 2025 |
Who can apply
This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.
All 15 applicant types the notice lists
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Is this a realistic fit?
- Projects NIH funded under this notice had a median yearly award of $652,377; it allows up to $500,000 per award.
- Most of the money in the 2 programs behind this notice (77% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
The purpose of this funding opportunity is to reduce health disparities through the development and translation of appropriate medical technologies. The NIH defines health disparities as differences in the incidence, prevalence, morbidity, mortality, and burden of diseases and other adverse health outcomes that exist among specific population groups. These population groups include racial and ethnic minorities (African Americans, American Indians, Alaska Natives, Asian Americans, Hispanic Americans, Native Hawaiians, and other U.S. Pacific Islanders, as well as subpopulations of all of these racial/ethnic groups), socioeconomically disadvantaged individuals, sexual and gender minorities, and medically underserved populations including individuals residing in rural and urban areas (see https://www.nimhd/nih.gov/about/overview/). This program seeks advances in medical technologies to reduce health disparities associated with diseases, illnesses, and conditions of public health importance. This announcement encourages applications to develop medical devices, imaging systems, robotic systems, biomaterial interfaces, synthetic biological systems, mathematical and modeling solutions, and other technologies to address the healthcare needs of populations that experience health disparities. Proposed medical technologies must have the following basic characteristics: effective, affordable, culturally acceptable, and easily accessible to those who need them. Responsive grant applications will involve a formal collaboration with a healthcare organization or public health agency serving one or more populations that experience health disparities.
Funded under RFA-EB-21-001 so far
NIH funded 7 projects under RFA-EB-21-001 in fiscal 2022 to 2026, at 7 institutions. The median yearly award was $652,377.
Who has won Minority Health and Health Disparities Research grants before
From fiscal 2021 to 2025, Minority Health and Health Disparities Research (93.307) awarded $2.0 billion across 1,237 grant awards, an average of $1.6 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| The Johns Hopkins University | Maryland | 37 | $69.3 million |
| The Trustees of Columbia University in the City of New York | New York | 25 | $59.1 million |
| University of Hawaii | Hawaii | 18 | $52.8 million |
| The Regents of the University of California, San Francisco | California | 24 | $49.5 million |
| The Morehouse School of Medicine, Inc. | Georgia | 4 | $44.1 million |
Who has won Discovery and Applied Research for Technological Innovations to Improve Human Health grants before
From fiscal 2021 to 2025, Discovery and Applied Research for Technological Innovations to Improve Human Health (93.286) awarded $1.8 billion across 1,983 grant awards, an average of $886,380 per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| The General Hospital Corporation | Massachusetts | 75 | $83.5 million |
| The Johns Hopkins University | Maryland | 68 | $83.5 million |
| The Leland Stanford Junior University | California | 64 | $53.0 million |
| Brigham & Womens Hospital Inc | Massachusetts | 41 | $49.5 million |
| The Trustees of the University of Pennsylvania | Pennsylvania | 44 | $48.3 million |
Applying now
This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is RFA-EB-21-001 still open?
No. It closed on May 2, 2025.
Who can apply for Technology Development to Reduce Health Disparities (R01 Clinical Trial Optional)?
National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.
What is the deadline for Technology Development to Reduce Health Disparities (R01 Clinical Trial Optional)?
Closed May 2, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.
How much funding is available?
Awards of up to $500,000 each.
Who has been funded under RFA-EB-21-001?
NIH RePORTER lists 7 projects funded under RFA-EB-21-001 in fiscal 2022 to 2026, at 7 institutions. The most were at Mainehealth, University of North Carolina Charlotte, Icahn School of Medicine at Mount Sinai.
Who has won Discovery and Applied Research for Technological Innovations to Improve Human Health grants before?
The largest recipients over five fiscal years were The General Hospital Corporation, The Johns Hopkins University, The Leland Stanford Junior University. The program made 1,983 awards worth $1.8 billion in that time.
Similar open grants
- NCCIH Natural Product Mid Phase Clinical Trial (R01 Clinical Trial Required)
- NCCIH Multi-Site Feasibility Clinical Trials of Mind and Body Interventions (R01 Clinical Trial Required)
- Investigator Initiated Clinical Trials of Complementary and Integrative Interventions Delivered Remotely or via mHealth (R01 Clinical Trial Required)
- Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)
- Competing Revisions to Existing NIH Single Project Research Grants and Cooperative Agreements (Clinical Trial Optional)
- Interventions to expand cancer screening and preventive services to ADVANCE health in populations that experience health disparities (R01, Clinical Trial Required)