RFA-DK-25-003: Silvio O. Conte Digestive Diseases Research Core Centers (P30 Clinical Trial Optional)
Closed
This grant is closed. A newer notice from the same program is open now: Silvio O. Conte Digestive Diseases Research Core Centers (P30-Clinical Trial Optional) (RFA-DK-27-119). Status: Closes February 10, 2027 (95 days left). It is in our archive of National Institutes of Health notices from 2023.
National Institutes of Health offered grants of up to $750,000 to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on October 23, 2024.
From the official notice on Grants.gov, last changed October 19, 2023. Checked November 7, 2026.
- Award ceiling$750,000
- Cost sharingNot required
- Funding typeGrant
About this NIH notice
- Activity codeP30
- Clinical trialsOptional
- Funded byNIDDK
- Median yearly award$195,056
- Typical project length32 years
- P30, Center Core Grant. Shared facilities and services for investigators who already hold research funding on a common theme. Other open P30 notices.
Projects funded under RFA-DK-25-003 were run by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK, 8 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.
Application due dates, page limits and budget limits are set in the notice. Read RFA-DK-25-003 in the NIH Guide.
Other notices with this title
| Notice | Posted | Deadline | Status |
|---|---|---|---|
| RFA-DK-27-119 | June 16, 2026 | Closes February 10, 2027 (95 days left) | Open |
| RFA-DK-21-026 | September 3, 2021 | Closed June 8, 2023 | Closed |
Key dates
| Posted | October 19, 2023 |
|---|---|
| Deadline | October 23, 2024 |
| Archived by Grants.gov | November 28, 2024 |
Who can apply
This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.
All 15 applicant types the notice lists
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Is this a realistic fit?
- Projects NIH funded under this notice had a median yearly award of $195,056; it allows up to $750,000 per award.
- Most of the program's money (70% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
This Notice of Funding Opportunity (NOFO) invites applications for Silvio O. Conte Digestive Diseases Research Core Centers (DDRCCs). The DDRCCs are part of an integrated program of digestive and liver diseases research support provided by the NIDDK. The purpose of this Centers program is to bring together basic and clinical investigators as a means to enhance communication, collaboration, and effectiveness of ongoing research related to digestive and/or liver diseases within the NIDDK's mission. DDRCCs are based on the core concept, whereby shared resources aimed at fostering productivity, synergy, and new research ideas among the funded investigators are supported in a cost-effective manner. Each proposed DDRCC must be organized around a central theme that reflects the focus of the digestive or liver diseases research of the Center members. The central theme must be within the primary mission ofthe NIDDK, and not thematic areas for which other NIH Institutes or Centers are considered the primary source of NIH funding.
Funded under RFA-DK-25-003 so far
NIH funded 8 projects under RFA-DK-25-003 in fiscal 2025 to 2026, at 8 institutions. The median yearly award was $195,056.
| Project | Institution | Fiscal year | Award |
|---|---|---|---|
| Cell Models Core | Medical University of South Carolina | 2026 | $178,295 |
| The Cleveland Digestive Diseases Research Core Center (DDRCC) | Case Western Reserve University | 2026 | $1.2 million |
| Integrated Cell and Microbial Biology of the GI Tract- Administrative Core | Boston Children's Hospital | 2026 | $292,809 |
| Administrative Core | Massachusetts General Hospital | 2026 | $181,298 |
| Gnotobiotics and Gut Microbiome Core | Cedars-Sinai Medical Center | 2026 | $306,079 |
| Admin Core | Yale University | 2026 | $217,661 |
| Large Animal Models Core | Univ of North Carolina Chapel Hill | 2026 | $164,186 |
| Host-environment interactions in the pathophysiology of digestive disease | Washington University | 2026 | $1.1 million |
Who has won Diabetes, Digestive, and Kidney Diseases Extramural Research grants before
From fiscal 2021 to 2025, Diabetes, Digestive, and Kidney Diseases Extramural Research (93.847) awarded $9.6 billion across 7,877 grant awards, an average of $1.2 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Regents of the University of Michigan | Michigan | 273 | $345 million |
| The Trustees of the University of Pennsylvania | Pennsylvania | 187 | $272 million |
| University of Pittsburgh - of the Commonwealth System of Higher Education | Pennsylvania | 209 | $238 million |
| The Washington University | Missouri | 187 | $227 million |
| The Regents of the University of California, San Francisco | California | 176 | $208 million |
Applying now
This notice no longer takes applications. Apply under the newer notice, RFA-DK-27-119, which is open now.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is RFA-DK-25-003 still open?
No. It closed on October 23, 2024. A newer notice is open: RFA-DK-27-119, closes February 10, 2027 (95 days left).
Who can apply for Silvio O. Conte Digestive Diseases Research Core Centers (P30 Clinical Trial Optional)?
National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.
What is the deadline for Silvio O. Conte Digestive Diseases Research Core Centers (P30 Clinical Trial Optional)?
Closed October 23, 2024. Applications are no longer accepted; the program's newer notices are on this page when there are any.
How much funding is available?
Awards of up to $750,000 each.
Who has been funded under RFA-DK-25-003?
NIH RePORTER lists 8 projects funded under RFA-DK-25-003 in fiscal 2025 to 2026, at 8 institutions. The most were at Medical University of South Carolina, Case Western Reserve University, Boston Children's Hospital.
Who has won Diabetes, Digestive, and Kidney Diseases Extramural Research grants before?
The largest recipients over five fiscal years were Regents of the University of Michigan, The Trustees of the University of Pennsylvania, University of Pittsburgh - of the Commonwealth System of Higher Education. The program made 7,877 awards worth $9.6 billion in that time.
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