RFA-DC-25-005: In Vivo High-Resolution Imaging for Inner Ear Visualization (R01 Clinical Trial optional)
Closed
This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2025.
National Institutes of Health offered grants of up to $500,000 to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. It expected to make $500,000 in total. Applications closed on October 1, 2026.
From the official notice on Grants.gov, last changed January 6, 2025. Checked November 7, 2026.
- Award ceiling$500,000
- Total funding$500,000
- Cost sharingNot required
- Funding typeGrant
About this NIH notice
- Activity codeR01
- Clinical trialsOptional
- Funded byNIDCD
- Median yearly award$692,124
- Typical project length5 years
- R01, Research Project Grant. NIH's standard grant for a defined research project led by a named investigator, usually for up to five years. Other open R01 notices.
Projects funded under RFA-DC-25-005 were run by National Institute on Deafness and Other Communication Disorders (NIDCD, 3 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.
Application due dates, page limits and budget limits are set in the notice. Read RFA-DC-25-005 in the NIH Guide.
Other notices with this title
| Notice | Posted | Deadline | Status |
|---|---|---|---|
| RFA-DC-24-004 | November 9, 2023 | Closed January 5, 2025 | Closed |
Key dates
| Posted | January 6, 2025 |
|---|---|
| Deadline | October 1, 2026 |
| Archived by Grants.gov | November 6, 2026 |
Who can apply
This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.
All 15 applicant types the notice lists
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Is this a realistic fit?
- Projects NIH funded under this notice had a median yearly award of $692,124; it allows up to $500,000 per award.
- Most of the program's money (77% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
This funding opportunity aims to support the development of in vivo high-resolution structural and functional imaging technologies for the living human inner ear. Proposed projects should focus on improving the resolution of current imaging techniques or developing new imaging techniques that can visualize inner ear structures in vivo with significantly greater detail and accuracy than currently possible. Both structural and functional aspects, including visualizing dynamic elements are important to development of new and improved techniques. Projects may also focus on developing new imaging probes or contrast agents that can enhance visualization of the inner ear structures. Ultimately, research supported in response to this RFA is to encourage technologies that allow, for example, structures such as hair cells, otoliths, membranes, ions, and vasculature to be viewed in detail in awake patients in a clinical setting using non-invasive techniques. To achieve this goal, a multi-disciplinary team approach that takes advantage of the expertise of each team member is highly encouraged. Studies in humans and intermediate studies in animals, but not non-mammalian species, may be proposed to develop or advance the needed technology. Any intermediate studies must articulate a clear path of the proposed methodology to application in awake humans or define the limitations and the usefulness in anesthetized humans.
Funded under RFA-DC-25-005 so far
NIH funded 3 projects under RFA-DC-25-005 in fiscal 2026, at 3 institutions. The median yearly award was $692,124.
| Project | Institution | Fiscal year | Award |
|---|---|---|---|
| Integrating histology and translational imaging of the human cochlea | Massachusetts Eye and Ear Infirmary | 2026 | $692,124 |
| New technologies for imaging of the human cochlea | University of Southern California | 2026 | $773,199 |
| Development of 7T MRI Techniques for Comprehensive Inner Ear Imaging | Johns Hopkins University | 2026 | $573,587 |
Who has won Research Related to Deafness and Communication Disorders grants before
From fiscal 2021 to 2025, Research Related to Deafness and Communication Disorders (93.173) awarded $2.1 billion across 2,231 grant awards, an average of $925,005 per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| The Johns Hopkins University | Maryland | 73 | $82.4 million |
| Massachusetts Eye and Ear Infirmary | Massachusetts | 41 | $78.9 million |
| The University of Iowa | Iowa | 28 | $53.4 million |
| The Leland Stanford Junior University | California | 39 | $46.2 million |
| University of Wisconsin System | Wisconsin | 56 | $45.0 million |
Applying now
This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is RFA-DC-25-005 still open?
No. It closed on October 1, 2026.
Who can apply for In Vivo High-Resolution Imaging for Inner Ear Visualization (R01 Clinical Trial optional)?
National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.
What is the deadline for In Vivo High-Resolution Imaging for Inner Ear Visualization (R01 Clinical Trial optional)?
Closed October 1, 2026. Applications are no longer accepted; the program's newer notices are on this page when there are any.
How much funding is available?
Awards of up to $500,000 each. About $500,000 in total.
Who has been funded under RFA-DC-25-005?
NIH RePORTER lists 3 projects funded under RFA-DC-25-005 in fiscal 2026, at 3 institutions. The most were at Massachusetts Eye and Ear Infirmary, University of Southern California, Johns Hopkins University.
Who has won Research Related to Deafness and Communication Disorders grants before?
The largest recipients over five fiscal years were The Johns Hopkins University, Massachusetts Eye and Ear Infirmary, The University of Iowa. The program made 2,231 awards worth $2.1 billion in that time.
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