RFA-AI-23-027: Immune Mechanisms at the Maternal-Fetal Interface (R01 Clinical Trial Not Allowed)
Closed
This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2023.
National Institutes of Health offered grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on October 11, 2023.
From the official notice on Grants.gov, last changed June 9, 2023. Checked November 7, 2026.
- Award amountsNot given on Grants.gov
- Cost sharingNot required
- Funding typeGrant
About this NIH notice
- Activity codeR01
- Clinical trialsNot allowed
- Funded byNIAID
- Median yearly award$588,060
- Typical project length5 years
- R01, Research Project Grant. NIH's standard grant for a defined research project led by a named investigator, usually for up to five years. Other open R01 notices.
Projects funded under RFA-AI-23-027 were run by National Institute of Allergy and Infectious Diseases (NIAID, 7 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.
Application due dates, page limits and budget limits are set in the notice. Read RFA-AI-23-027 in the NIH Guide.
Key dates
| Posted | June 9, 2023 |
|---|---|
| Deadline | October 11, 2023 |
| Archived by Grants.gov | November 16, 2023 |
Who can apply
This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.
All 15 applicant types the notice lists
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Is this a realistic fit?
- Most of the program's money (67% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
The purpose of this Funding Opportunity Announcement (FOA) is to solicit applications to: improve the understanding of the roles and interactions of immune cells at the maternal-fetal interface that support pregnancy and enable optimal placental development and function; and elucidate the mechanisms by which infection, vaccination, or environmental perturbations during gestation modulate immune responses in the pregnant individual and alter systemic or tissue-specific immunity in the offspring.
Funded under RFA-AI-23-027 so far
NIH funded 7 projects under RFA-AI-23-027 in fiscal 2024 to 2026, at 7 institutions. The median yearly award was $588,060.
| Project | Institution | Fiscal year | Award |
|---|---|---|---|
| The role of placental macrophages in cytomegalovirus infection at the maternal-fetal interface | Imperial College of Science, Technology and Medicine | 2026 | $386,588 |
| Glycan regulation of fetomaternal tolerance | University of California, San Francisco | 2026 | $655,821 |
| Innate Allorecognition at the Maternal-Fetal Interface | Stanford University | 2026 | $656,090 |
| Mechanistic insights into the kinetics of Fc receptor-mediated placental antibody transfer to optimize maternal vaccine strategies | University of Virginia | 2026 | $470,417 |
| Parity, paternity and pregnancy outcomes | Cincinnati Childrens Hosp Med Ctr | 2026 | $627,048 |
| T Cells and IL-9 Signaling at the Maternal-Fetal Interface in Preterm Labor and Birth | Washington University | 2026 | $588,405 |
| Maternal B cells in health and disease. | Sloan-Kettering Inst Can Research | 2026 | $703,416 |
Who has won Allergy and Infectious Diseases Research grants before
From fiscal 2021 to 2025, Allergy and Infectious Diseases Research (93.855) awarded $22 billion across 13,282 grant awards, an average of $1.6 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Fred Hutchinson Cancer Center | Washington | 85 | $938 million |
| Duke University | North Carolina | 230 | $781 million |
| University of California, Los Angeles | California | 138 | $745 million |
| The Johns Hopkins University | Maryland | 321 | $668 million |
| Emory University | Georgia | 282 | $650 million |
Applying now
This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is RFA-AI-23-027 still open?
No. It closed on October 11, 2023.
Who can apply for Immune Mechanisms at the Maternal-Fetal Interface (R01 Clinical Trial Not Allowed)?
National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.
What is the deadline for Immune Mechanisms at the Maternal-Fetal Interface (R01 Clinical Trial Not Allowed)?
Closed October 11, 2023. Applications are no longer accepted; the program's newer notices are on this page when there are any.
Who has been funded under RFA-AI-23-027?
NIH RePORTER lists 7 projects funded under RFA-AI-23-027 in fiscal 2024 to 2026, at 7 institutions. The most were at Imperial College of Science, Technology and Medicine, University of California, San Francisco, Stanford University.
Who has won Allergy and Infectious Diseases Research grants before?
The largest recipients over five fiscal years were Fred Hutchinson Cancer Center, Duke University, University of California, Los Angeles. The program made 13,282 awards worth $22 billion in that time.
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