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Grants / Department of Health and Human Services / National Institutes of Health

RFA-AI-23-022: Animal Models for Hepatitis B and C (R01 Clinical Trial Not Allowed)

Closed Closed August 25, 2023 Opportunity RFA-AI-23-022

This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2023.

National Institutes of Health offered grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on August 25, 2023.

From the official notice on Grants.gov, last changed March 28, 2023. Checked November 7, 2026.

About this NIH notice

Projects funded under RFA-AI-23-022 were run by National Institute of Allergy and Infectious Diseases (NIAID, 5 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.

Application due dates, page limits and budget limits are set in the notice. Read RFA-AI-23-022 in the NIH Guide.

Key dates

PostedMarch 28, 2023
DeadlineAugust 25, 2023
Archived by Grants.govSeptember 30, 2023

Who can apply

This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

All 15 applicant types the notice lists

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses.

Is this a realistic fit?

What the grant funds

This Funding Opportunity Announcement (FOA) encourages research focused on the development of convenient small animal models that will support infection and replication of HBV and/or HCV, ideally leading to the dichotomous outcomes of clearance and persistence. Alternatively, closely related surrogate virus-host systems or robust xenotransplantation models dually engrafted with human liver cells and human immune systems can be developed.

Category: Health.

Funded under RFA-AI-23-022 so far

NIH funded 5 projects under RFA-AI-23-022 in fiscal 2024 to 2026, at 5 institutions. The median yearly award was $780,961.

Recently funded projects
ProjectInstitutionFiscal yearAward
Animal Model to study heterogeneous outcomes of HCV Infection and Pathogenesis R01Research Inst Nationwide Children's Hosp2026$780,961
Developing Woodchucks Susceptible to Hepatitis B Virus Infection by Modifying the Virus or Host R01Georgetown University2026$799,541
Development of a hamster model for hepatitis B virus infection R01Utah State University2026$718,533
Novel mouse models of hepatitis B virus infection and replication R01Wake Forest University Health Sciences2026$708,659
Breaching the species barrier: Towards an immunocompetent HBV-susceptible mouse model R01Rockefeller University2026$786,722

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Allergy and Infectious Diseases Research grants before

From fiscal 2021 to 2025, Allergy and Infectious Diseases Research (93.855) awarded $22 billion across 13,282 grant awards, an average of $1.6 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
Fred Hutchinson Cancer CenterWashington85$938 million
Duke UniversityNorth Carolina230$781 million
University of California, Los AngelesCalifornia138$745 million
The Johns Hopkins UniversityMaryland321$668 million
Emory UniversityGeorgia282$650 million

Top states: California ($3.4 billion), Massachusetts ($2.1 billion), Washington ($1.9 billion), New York ($1.8 billion), North Carolina ($1.5 billion).

Applying now

This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is RFA-AI-23-022 still open?

No. It closed on August 25, 2023.

Who can apply for Animal Models for Hepatitis B and C (R01 Clinical Trial Not Allowed)?

National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for Animal Models for Hepatitis B and C (R01 Clinical Trial Not Allowed)?

Closed August 25, 2023. Applications are no longer accepted; the program's newer notices are on this page when there are any.

Who has been funded under RFA-AI-23-022?

NIH RePORTER lists 5 projects funded under RFA-AI-23-022 in fiscal 2024 to 2026, at 5 institutions. The most were at Research Inst Nationwide Children's Hosp, Georgetown University, Utah State University.

Who has won Allergy and Infectious Diseases Research grants before?

The largest recipients over five fiscal years were Fred Hutchinson Cancer Center, Duke University, University of California, Los Angeles. The program made 13,282 awards worth $22 billion in that time.

Similar open grants