NSF PD-23-1491: Cellular and Biochemical Engineering
Closed
This grant is closed. A newer notice from the same program is open now: Major Research Instrumentation Program: (MRI) (NSF 27-500). Status: Closes January 29, 2027 (83 days left). It is in our archive of U.S. National Science Foundation notices from 2023.
U.S. National Science Foundation offered grants to any type of organization. It is no longer open on Grants.gov.
From the official notice on Grants.gov, last changed August 12, 2026. Checked November 7, 2026.
- Award amountsNot given on Grants.gov
- Cost sharingNot required
- Funding typeGrant
Other notices with this title
| Notice | Posted | Deadline | Status |
|---|---|---|---|
| NSF PD-20-1491 | June 6, 2025 | Closed | Closed |
| NSF PD-17-1491 | June 6, 2025 | Closed | Closed |
| NSF PD-18-1491 | June 6, 2025 | Closed | Closed |
Key dates
| Posted | June 18, 2023 |
|---|---|
| Archived by Grants.gov | August 13, 2026 |
Who can apply
This opportunity was open to any type of organization.
- Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"
Is this a realistic fit?
- Most of the program's money (89% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
Synopsis The Cellular and Biochemical Engineering (CBE) program is part of the Engineering Biology and Health cluster, which also includes: 1) the Biophotonics program; 2) the Biosensing program; 3) the Disability and Rehabilitation Engineering program; and 4) the Engineering of Biomedical Systems program. The Cellular and Biochemical Engineering program supports fundamental engineering research that advances understanding of cellular and biomolecular processes. CBE-funded research may lead to the development of enabling technology for advanced biomanufacturing of therapeutic cells, biochemicals, and biopharmaceuticals, and for other biotechnology industrie . The program encourages highly innovative and potentially transformative engineering research leading to novel bioprocessing and biomanufacturing approaches. Fundamental to many CBE research projects is the understanding of how biomolecules, subcellular systems, cells, and cell populations interact, and how those interactions lead to changes in structure, function, and behavior. A quantitative treatment of problems related to biological processes is considered vital to successful research projects in the CBE program. Major areas of interest for the program include: Metabolic engineering and synthetic biology for biomanufacturing, The design of synthetic metabolic components and synthetic cells, Microbiome structure, function, maintenance, and design, Protein and enzyme engineering, and Design of integrated chemoenzymatic systems. The CBE program also encourages proposals that effectively integrate knowledge and practices from different disciplines while incorporating ongoing research into educational activities. All proposals should include a description on the potential impact of proposed research on an associated biomanufacturing process. Proposals whose core innovation involves tissue engineering, organ culture, development of models of healthy or diseased physiology, or design and application of technologies focused on the diagnosis or treatment of disease should be submitted to the Engineering of Biomedical Systems program (CBET 5345). Innovative proposals outside of these specific interest areas may be considered. However, prior to submission, it is recommended that the Principal Investigator contact the program director to avoid the possibility of the proposal being returned without review.
Who has won Engineering grants before
From fiscal 2021 to 2025, Engineering (47.041) awarded $4.3 billion across 11,244 grant awards, an average of $385,774 per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Georgia Tech Research Corp | Georgia | 193 | $106 million |
| Purdue University | Indiana | 238 | $106 million |
| Regents of the University of Michigan | Michigan | 250 | $101 million |
| University of California, San Diego | California | 114 | $96.4 million |
| The Trustees of the University of Pennsylvania | Pennsylvania | 59 | $80.6 million |
Applying now
This notice no longer takes applications. Apply under the newer notice, NSF 27-500, which is open now.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is NSF PD-23-1491 still open?
No. It is no longer open on Grants.gov. A newer notice is open: NSF 27-500, closes January 29, 2027 (83 days left).
Who can apply for Cellular and Biochemical Engineering?
U.S. National Science Foundation accepted applications from any type of organization.
What is the deadline for Cellular and Biochemical Engineering?
Closed. Applications are no longer accepted; the program's newer notices are on this page when there are any.
Who has won Engineering grants before?
The largest recipients over five fiscal years were Georgia Tech Research Corp, Purdue University, Regents of the University of Michigan. The program made 11,244 awards worth $4.3 billion in that time.