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Grants / Department of Health and Human Services / National Institutes of Health

PAS-22-206: HEAL Initiative: Career Development Awards in Implementation Science for Substance Use Prevention and Treatment (K01 - Clinical Trial Required)

Closed Closed November 12, 2025 Opportunity PAS-22-206

This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2022.

National Institutes of Health offered grants of up to $275,000 to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on November 12, 2025.

From the official notice on Grants.gov, last changed July 14, 2022. Checked November 7, 2026.

About this NIH notice

Projects funded under PAS-22-206 were run by National Institute on Drug Abuse (NIDA, 5 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.

Application due dates, page limits and budget limits are set in the notice. Read PAS-22-206 in the NIH Guide.

Key dates

PostedJuly 14, 2022
DeadlineNovember 12, 2025
Archived by Grants.govDecember 18, 2025

Who can apply

This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

All 15 applicant types the notice lists

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses.

Is this a realistic fit?

What the grant funds

This HEAL FOA provides an opportunity for early career researchers or early career clinicians with foundational backgrounds in addiction to develop expertise in implementation science. Successful applicants would propose training in implementation science methods, and a research project that would apply these to at least one of the four priority domains of the HHS Overdose Prevention Strategy: primary prevention (including appropriate opioid prescribing), OUD treatment, harm reduction, and/or recovery support services. The overarching goal is to build a cadre of implementation researchers who can contribute to addressing the current overdose crisis, develop research careers that will impact the quality of addiction clinical practice generally, and become the next generation of implementation experts and mentors.

Category: Education, Health.

Funded under PAS-22-206 so far

NIH funded 5 projects under PAS-22-206 in fiscal 2023 to 2026, at 5 institutions. The median yearly award was $189,903.

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Cancer Treatment Research grants before

From fiscal 2021 to 2025, Cancer Treatment Research (93.395) awarded $5.6 billion across 3,622 grant awards, an average of $1.5 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Univeristy of Texas M.D. Anderson Cancer CenterTexas144$188 million
Dana-Farber Cancer Institute, Inc.Massachusetts68$185 million
Icahn School of Medicine at Mount SinaiNew York35$179 million
Public Health InstituteCalifornia4$168 million
Fred Hutchinson Cancer CenterWashington57$156 million

Top states: California ($843 million), New York ($604 million), Massachusetts ($568 million), Texas ($444 million), Pennsylvania ($417 million).

Who has won Cancer Biology Research grants before

From fiscal 2021 to 2025, Cancer Biology Research (93.396) awarded $4.3 billion across 3,142 grant awards, an average of $1.4 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Trustees of Columbia University in the City of New YorkNew York70$151 million
The Univeristy of Texas M.D. Anderson Cancer CenterTexas109$144 million
Sloan-Kettering Institute for Cancer ResearchNew York66$136 million
Dana-Farber Cancer Institute, Inc.Massachusetts47$107 million
The Regents of the University of California, San FranciscoCalifornia64$95.5 million

Top states: New York ($712 million), California ($608 million), Massachusetts ($409 million), Texas ($373 million), Pennsylvania ($286 million).

Who has won Cancer Cause and Prevention Research grants before

From fiscal 2021 to 2025, Cancer Cause and Prevention Research (93.393) awarded $3.6 billion across 2,517 grant awards, an average of $1.4 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Univeristy of Texas M.D. Anderson Cancer CenterTexas81$107 million
Sloan-Kettering Institute for Cancer ResearchNew York65$99.1 million
The Trustees of Columbia University in the City of New YorkNew York48$85.3 million
Dana-Farber Cancer Institute, Inc.Massachusetts51$83.1 million
University of North Carolina at Chapel HillNorth Carolina49$76.1 million

Top states: California ($465 million), New York ($445 million), Massachusetts ($350 million), Texas ($259 million), Pennsylvania ($175 million).

Other programs behind this notice

Applying now

This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is PAS-22-206 still open?

No. It closed on November 12, 2025.

Who can apply for HEAL Initiative: Career Development Awards in Implementation Science for Substance Use Prevention and Treatment (K01 - Clinical Trial Required)?

National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for HEAL Initiative: Career Development Awards in Implementation Science for Substance Use Prevention and Treatment (K01 - Clinical Trial Required)?

Closed November 12, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

Awards of up to $275,000 each.

Who has been funded under PAS-22-206?

NIH RePORTER lists 5 projects funded under PAS-22-206 in fiscal 2023 to 2026, at 5 institutions. The most were at Washington University, Utah State Higher Education System--University of Utah, Hennepin Healthcare Research Institute.

Who has won Cancer Cause and Prevention Research grants before?

The largest recipients over five fiscal years were The Univeristy of Texas M.D. Anderson Cancer Center, Sloan-Kettering Institute for Cancer Research, The Trustees of Columbia University in the City of New York. The program made 2,517 awards worth $3.6 billion in that time.

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