PAS-22-096: Stimulating Hematology Investigation: New Endeavors (SHINE) (R01 Clinical Trial Not Allowed)
Closed
This grant is closed. A newer notice from the same program is open now: Stimulating Hematology Investigation: New Endeavors (SHINE) (R01 Clinical Trial Not Allowed) (PAS-25-205). Status: Closes January 6, 2028 (425 days left). It is in our archive of National Institutes of Health notices from 2021.
National Institutes of Health offered grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on December 10, 2024.
From the official notice on Grants.gov, last changed November 6, 2024. Checked November 7, 2026.
- Award amountsNot given on Grants.gov
- Cost sharingNot required
- Funding typeGrant
About this NIH notice
- Activity codeR01
- Clinical trialsNot allowed
- Funded byNIDDK, NHLBI, NIA
- Median yearly award$500,000
- Typical project length4 years
- R01, Research Project Grant. NIH's standard grant for a defined research project led by a named investigator, usually for up to five years. Other open R01 notices.
Projects funded under PAS-22-096 were run by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK, 41 projects), National Heart Lung and Blood Institute (NHLBI, 22 projects) and National Institute on Aging (NIA, 3 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.
Application due dates, page limits and budget limits are set in the notice. Read PAS-22-096 in the NIH Guide.
Other notices with this title
| Notice | Posted | Deadline | Status |
|---|---|---|---|
| PAS-25-205 | November 6, 2024 | Closes January 6, 2028 (425 days left) | Open |
Key dates
| Posted | December 22, 2021 |
|---|---|
| Deadline | December 10, 2024 |
| Archived by Grants.gov | January 9, 2025 |
Who can apply
This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.
All 15 applicant types the notice lists
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Is this a realistic fit?
- Most of the money in the 2 programs behind this notice (72% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
The Stimulating Hematology Investigation: New Endeavors (SHINE) program is intended to promote innovative, high-quality nonmalignant hematology research relevant to the missions of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institute of Aging (NIA), and the National Heart, Lung, and Blood Institute (NHLBI). Investigator-initiated research project grant applications (R01s) in specific areas of basic and early translational hematology research are invited to this program that supports growth in the nonmalignant hematology research domain. Specific emerging topics that are at the l?e?a?d?i?n?g? ?e?d?g?e? of the field will change over time and will be updated annually through the NIH Guide to Grants and Contracts and hyperlinked to this FOA.
Funded under PAS-22-096 so far
NIH funded 66 projects under PAS-22-096 in fiscal 2022 to 2026, at 42 institutions. The median yearly award was $500,000.
| Project | Institution | Fiscal year | Award |
|---|---|---|---|
| Hematopoietic Regulation via GATA Switches | University of Wisconsin-Madison | 2026 | $577,708 |
| Diabetic Memory in Hematopoietic Stem Cells | Cincinnati Childrens Hosp Med Ctr | 2026 | $436,663 |
| Molecular Mechanisms of MDS pathogenesis with aging | Columbia University Health Sciences | 2026 | $500,000 |
| Molecular mechanism underlying clonal expansion of hematopoietic stem cells | Northwestern University | 2026 | $664,714 |
| The role of SRCAP in therapy related clonal hematopoiesis | Brigham and Women's Hospital | 2026 | $508,759 |
| The molecular pathophysiology of the congenital dyserythropoietic anemias | University of Michigan at Ann Arbor | 2026 | $744,722 |
| Control of hematopoietic maturation by Lin28b/let-7 | Boston Children's Hospital | 2026 | $354,000 |
| Establishing CUX1 as a determinant of hematopoietic stem cell fate | University of Chicago | 2026 | $465,400 |
Who has won Aging Research grants before
From fiscal 2021 to 2025, Aging Research (93.866) awarded $19 billion across 11,026 grant awards, an average of $1.7 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| The Regents of the University of California, San Francisco | California | 337 | $575 million |
| The Trustees of Columbia University in the City of New York | New York | 242 | $574 million |
| University of Southern California | California | 203 | $572 million |
| The Washington University | Missouri | 210 | $556 million |
| Regents of the University of Michigan | Michigan | 232 | $538 million |
Who has won Diabetes, Digestive, and Kidney Diseases Extramural Research grants before
From fiscal 2021 to 2025, Diabetes, Digestive, and Kidney Diseases Extramural Research (93.847) awarded $9.6 billion across 7,877 grant awards, an average of $1.2 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Regents of the University of Michigan | Michigan | 273 | $345 million |
| The Trustees of the University of Pennsylvania | Pennsylvania | 187 | $272 million |
| University of Pittsburgh - of the Commonwealth System of Higher Education | Pennsylvania | 209 | $238 million |
| The Washington University | Missouri | 187 | $227 million |
| The Regents of the University of California, San Francisco | California | 176 | $208 million |
Applying now
This notice no longer takes applications. Apply under the newer notice, PAS-25-205, which is open now.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is PAS-22-096 still open?
No. It closed on December 10, 2024. A newer notice is open: PAS-25-205, closes January 6, 2028 (425 days left).
Who can apply for Stimulating Hematology Investigation: New Endeavors (SHINE) (R01 Clinical Trial Not Allowed)?
National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.
What is the deadline for Stimulating Hematology Investigation: New Endeavors (SHINE) (R01 Clinical Trial Not Allowed)?
Closed December 10, 2024. Applications are no longer accepted; the program's newer notices are on this page when there are any.
Who has been funded under PAS-22-096?
NIH RePORTER lists 66 projects funded under PAS-22-096 in fiscal 2022 to 2026, at 42 institutions. The most were at University of Wisconsin-Madison, Cincinnati Childrens Hosp Med Ctr, Boston Children's Hospital.
Who has won Diabetes, Digestive, and Kidney Diseases Extramural Research grants before?
The largest recipients over five fiscal years were Regents of the University of Michigan, The Trustees of the University of Pennsylvania, University of Pittsburgh - of the Commonwealth System of Higher Education. The program made 7,877 awards worth $9.6 billion in that time.
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