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Grants / Department of Health and Human Services / National Institutes of Health

PAR-27-103: Enhancement and Management of Established Biomedical Data Repositories and Knowledgebases (R24 Clinical Trial Not Allowed)

Forecast Expected deadline September 25, 2026 Opportunity PAR-27-103

This forecast is out of date. Its expected dates have passed and the agency has not posted the opportunity on Grants.gov. It may be delayed or cancelled; check the program's other opportunities below.

National Institutes of Health plans to offer grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. It is a forecast: the notice is expected around July 24, 2026, with applications due around September 25, 2026.

From the official notice on Grants.gov, last changed May 12, 2026. Checked November 7, 2026.

About this NIH notice

Application due dates, page limits and budget limits are set in the notice. Read PAR-27-103 in the NIH Guide.

Key dates

Forecast postedMay 12, 2026
Expected postingJuly 24, 2026
Expected deadlineSeptember 25, 2026
Expected award dateJuly 30, 2027

Add the deadline to your calendar or it to My grants.

Who can apply

This opportunity is open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

All 15 applicant types the notice lists

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses.

Is this a realistic fit?

What the grant funds

The Office of Data Science Strategy (ODSS) along with other participating institutes and Centers intends to renew the Notice of Funding Opportunity (NOFO) PAR-23-237. This funding opportunity is intended to provide continuation to support established biomedical data repositories and knowledge bases as distinct and separate resources that have demonstrated impact and have potential for continued benefit to the community served. Applications funded under this NOFO for established data resources must already exist, address the needs of the targeted biomedical research community, document scientific impact they have had thus far, and have potential for continued benefit to the community served. No applications are being solicited at this time. Given the expiration of PAR-23-237, this notice will allow for potential applicants the opportunity to continue developing high-impact applications to renew funding support for existing high-performing data repositories and knowledge bases.

Category: Health.

Who has won Trans-NIH Research Support grants before

From fiscal 2021 to 2025, Trans-NIH Research Support (93.310) awarded $5.9 billion across 4,433 grant awards, an average of $1.3 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
Duke UniversityNorth Carolina66$219 million
The Leland Stanford Junior UniversityCalifornia104$176 million
University of Pittsburgh - of the Commonwealth System of Higher EducationPennsylvania82$154 million
The Johns Hopkins UniversityMaryland95$152 million
Yale UnivConnecticut85$149 million

Top states: California ($992 million), Massachusetts ($571 million), New York ($548 million), Pennsylvania ($445 million), North Carolina ($387 million).

How to apply

  1. Read the full notice and attachments on Grants.gov. The notice is the official source for deadlines and requirements.
  2. Make sure your organization has an active SAM.gov registration and Unique Entity ID; registration can take several weeks.
  3. Register on Grants.gov and submit through Workspace before the deadline and time given in the notice. Our application guide walks through each step.

Questions go to Office of Data Science Strategy (ODSS), drkb-foa@nih.gov, Please contact via e-mail..

Open the official notice

Questions people ask

Is PAR-27-103 still open?

Not yet. It is a forecast: expected deadline September 25, 2026.

Who can apply for Enhancement and Management of Established Biomedical Data Repositories and Knowledgebases (R24 Clinical Trial Not Allowed)?

National Institutes of Health accepts applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for Enhancement and Management of Established Biomedical Data Repositories and Knowledgebases (R24 Clinical Trial Not Allowed)?

Expected deadline September 25, 2026. Confirm the date and time in the official notice on Grants.gov.

Who has won Trans-NIH Research Support grants before?

The largest recipients over five fiscal years were Duke University, The Leland Stanford Junior University, University of Pittsburgh - of the Commonwealth System of Higher Education. The program made 4,433 awards worth $5.9 billion in that time.

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