PAR-26-081: Complex Integrated Multi-Component Projects in Aging Research (U19 Clinical Trial Optional)
Forecast
This forecast is out of date. Its expected dates have passed and the agency has not posted the opportunity on Grants.gov. It may be delayed or cancelled; check the program's other opportunities below.
National Institutes of Health plans to offer grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. It is a forecast: the notice is expected around March 25, 2026, with applications due around May 25, 2026.
From the official notice on Grants.gov, last changed November 24, 2025. Checked November 7, 2026.
- Award amountsNot given on Grants.gov
- Cost sharingNot required
- Funding typeCooperative Agreement
About this NIH notice
- Activity codeU19
- Clinical trialsOptional
- U19, Research Program Cooperative Agreement. Several related projects under one award, with substantial NIH involvement. Other open U19 notices.
Application due dates, page limits and budget limits are set in the notice. Read PAR-26-081 in the NIH Guide.
Other notices with this title
| Notice | Posted | Deadline | Status |
|---|---|---|---|
| PAR-22-213 | July 7, 2022 | Closed September 25, 2025 | Closed |
Key dates
| Forecast posted | November 24, 2025 |
|---|---|
| Expected posting | March 25, 2026 |
| Expected deadline | May 25, 2026 |
| Expected award date | April 25, 2027 |
Add the deadline to your calendar or it to My grants.
Who can apply
This opportunity is open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.
All 15 applicant types the notice lists
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations.
Is this a realistic fit?
- Most of the program's money (73% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
The National Institute on Aging (NIA) intends to publish a Notice of Funding Opportunity (NOFO) that invites applications that propose large-scale, complex research projects with multiple highly integrated components focused on a common research question relevant to aging. Applications will involve a well-integrated research program composed of a multidisciplinary team of investigators within a single institution or a consortium of institutions. Applications will demonstrate how the individual components will be synergistically integrated to advance understanding of the unifying hypothesis or theme. The structure and approach of proposed projects will vary depending on the hypotheses under investigation; however, all applications are expected to reflect a high level of coordination among components that ensures integration across the projects. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO intends to utilize the U19 activity code. Investigators with expertise and insights into this area of aging research are encouraged to begin to consider applying for this new NOFO.
Who has won Aging Research grants before
From fiscal 2021 to 2025, Aging Research (93.866) awarded $19 billion across 11,026 grant awards, an average of $1.7 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| The Regents of the University of California, San Francisco | California | 337 | $575 million |
| The Trustees of Columbia University in the City of New York | New York | 242 | $574 million |
| University of Southern California | California | 203 | $572 million |
| The Washington University | Missouri | 210 | $556 million |
| Regents of the University of Michigan | Michigan | 232 | $538 million |
How to apply
- Read the full notice and attachments on Grants.gov. The notice is the official source for deadlines and requirements.
- Make sure your organization has an active SAM.gov registration and Unique Entity ID; registration can take several weeks.
- Register on Grants.gov and submit through Workspace before the deadline and time given in the notice. Our application guide walks through each step.
Questions go to NIA Scientific Contact, nia_scicontact@mail.nih.gov, N/A.
Questions people ask
Is PAR-26-081 still open?
Not yet. It is a forecast: expected deadline May 25, 2026.
Who can apply for Complex Integrated Multi-Component Projects in Aging Research (U19 Clinical Trial Optional)?
National Institutes of Health accepts applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.
What is the deadline for Complex Integrated Multi-Component Projects in Aging Research (U19 Clinical Trial Optional)?
Expected deadline May 25, 2026. Confirm the date and time in the official notice on Grants.gov.
Who has won Aging Research grants before?
The largest recipients over five fiscal years were The Regents of the University of California, San Francisco, The Trustees of Columbia University in the City of New York, University of Southern California. The program made 11,026 awards worth $19 billion in that time.
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