PAR-25-166: NIDCR Small Research Grants for Analyses of Existing Genomics Data (R03 Clinical Trial Not Allowed)
Closed
This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2024.
National Institutes of Health offered grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on May 7, 2026.
From the official notice on Grants.gov, last changed November 18, 2024. Checked November 7, 2026.
- Award amountsNot given on Grants.gov
- Cost sharingNot required
- Funding typeGrant
About this NIH notice
- Activity codeR03
- Clinical trialsNot allowed
- Funded byNIDCR
- Median yearly award$308,000
- Typical project length2 years
- R03, Small Grant. A small, short project such as pilot work, a feasibility study, secondary data analysis or a new method, usually for up to two years. Other open R03 notices.
Projects funded under PAR-25-166 were run by National Institute of Dental and Craniofacial Research (NIDCR, 7 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.
Application due dates, page limits and budget limits are set in the notice. Read PAR-25-166 in the NIH Guide.
Other notices with this title
| Notice | Posted | Deadline | Status |
|---|---|---|---|
| PAR-23-132 | March 28, 2023 | Closed January 7, 2025 | Closed |
Key dates
| Posted | November 18, 2024 |
|---|---|
| Deadline | May 7, 2026 |
| Archived by Grants.gov | June 12, 2026 |
Who can apply
This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.
All 15 applicant types the notice lists
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Is this a realistic fit?
- Most of the program's money (76% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
The purpose of this NOFO is to announce support for meritorious research projects that address research questions relevant to human dental, oral, or craniofacial (DOC) biology, and diseases and conditions, through analysis of existing and publicly available genomic data, with or without other types of complementary data, using statistical and computational approaches. Data analysis for each project can be performed using existing and/or novel methods to be developed in the proposed project(s), including methods for data and metadata mining, data integration, and Artificial Intelligence (AI)/Machine Learning (ML)/Deep Learning (DL) methods. In addition to analysis of existing data, experimental or in silico work is required to validate the results of the proposed analysis , or to validate a newly developed analytic method. Projects aimed at understanding oral health disparities to inform strategies for improving health for all individuals are a priority. Projects focused on investigating and/or characterizing human biological pathways to inform identification of intervention targets or defining the pathogenicity of known genetic variants are encouraged.
Funded under PAR-25-166 so far
NIH funded 7 projects under PAR-25-166 in fiscal 2026, at 6 institutions. The median yearly award was $308,000.
| Project | Institution | Fiscal year | Award |
|---|---|---|---|
| DNA Methylation Signatures in High-Impact Temporomandibular Disorders and General Chronic Pain Conditions | University of Minnesota | 2026 | $308,000 |
| A functional smoothed machine learning approach for high-dimensional orofacial clefts genetic data analysis | University of New Hampshire | 2026 | $299,950 |
| Spatial Dissection of Pathogenic Endotypes and Therapeutic Mechanisms in Sjögren's Disease | Virginia Commonwealth University | 2026 | $310,500 |
| An Atlas of Bacterial Physiology in the Human Oral Cavity | Case Western Reserve University | 2026 | $340,149 |
| Revealing the Trajectory and Critical Roles of Retinoic Acid in Ameloblast Differentiation | University of Michigan at Ann Arbor | 2026 | $312,000 |
| Statistical and Computational Methods for Rare Biosphere | University of Michigan at Ann Arbor | 2026 | $275,868 |
| Unveiling Therapeutic Targets for Precision Intervention in HPV-Associated Oral Cancers through Genomic Analysis | University of Arizona | 2026 | $284,714 |
Who has won Oral Diseases and Disorders Research grants before
From fiscal 2021 to 2025, Oral Diseases and Disorders Research (93.121) awarded $1.9 billion across 2,263 grant awards, an average of $818,037 per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Regents of the University of Michigan | Michigan | 76 | $89.2 million |
| The Regents of the University of California, San Francisco | California | 84 | $80.5 million |
| University of Southern California | California | 41 | $78.6 million |
| University of Pittsburgh - of the Commonwealth System of Higher Education | Pennsylvania | 58 | $55.9 million |
| The Trustees of the University of Pennsylvania | Pennsylvania | 66 | $51.5 million |
Applying now
This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is PAR-25-166 still open?
No. It closed on May 7, 2026.
Who can apply for NIDCR Small Research Grants for Analyses of Existing Genomics Data (R03 Clinical Trial Not Allowed)?
National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.
What is the deadline for NIDCR Small Research Grants for Analyses of Existing Genomics Data (R03 Clinical Trial Not Allowed)?
Closed May 7, 2026. Applications are no longer accepted; the program's newer notices are on this page when there are any.
Who has been funded under PAR-25-166?
NIH RePORTER lists 7 projects funded under PAR-25-166 in fiscal 2026, at 6 institutions. The most were at University of Michigan at Ann Arbor, University of Minnesota, University of New Hampshire.
Who has won Oral Diseases and Disorders Research grants before?
The largest recipients over five fiscal years were Regents of the University of Michigan, The Regents of the University of California, San Francisco, University of Southern California. The program made 2,263 awards worth $1.9 billion in that time.
Similar open grants
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- Pilot Projects to Enhance the Human Virome Program (R03 Clinical Trials Not Allowed)
- Pilot Projects Investigating Understudied Proteins Associated with Rare Diseases (R03 Clinical Trial Not Allowed)
- Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed)
- NICHD Small Research Grant Program (R03 Clinical Trial Required)